The PDK1 Inhibitor Dichloroacetate Controls Cholesterol Homeostasis Through the ERK5/MEF2 Pathway (Q41632623)

5 October 2017

The PDK1 Inhibitor Dichloroacetate Controls Cholesterol Homeostasis Through the ERK5/MEF2 Pathway (English)

1 reference

5 October 2017

0 references

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28878225%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Sabine Gerbal-Chaloin

4

1 reference

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12 June 2020

Stefania Orecchioni

8

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12 June 2020

Francesco Bertolini

10

1 reference

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12 June 2020

Milica Bozic

11

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12 June 2020

Jose M Valdivielso

12

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12 June 2020

Isabel C Lopez-Mejia

15

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12 June 2020

Lluis Fajas

16

1 reference

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12 June 2020

Javier Hernandez

18

1 reference

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12 June 2020

Martin Villalba

20

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12 June 2020

author name string

Abrar Ul Haq Khan

1

1 reference

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12 June 2020

Delphine Gitenay

3

1 reference

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12 June 2020

Claire Gondeau

5

1 reference

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12 June 2020

Dang-Nghiem Vo

6

1 reference

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12 June 2020

Sana Belkahla

7

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12 June 2020

Giovanna Talarico

9

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12 June 2020

Fabienne Bejjani

13

1 reference

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12 June 2020

Isabelle Jariel

14

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12 June 2020

Charles-Henri Lecellier

17

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12 June 2020

Martine Daujat

19

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12 June 2020

language of work or name

English

0 references

publication date

6 September 2017

1 reference

5 October 2017

1 reference

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12 June 2020

volume

7

1 reference

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12 June 2020

issue

1

1 reference

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12 June 2020

page(s)

10654

1 reference

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Creative Commons Attribution 4.0 International

12 June 2020

copyright license

start time

6 September 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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6 October 2017

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Interaction between Glucose and Lipid Metabolism: More than Diabetic Dyslipidemia

6 October 2017

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6 October 2017

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The presence of wild type p53 in hematological cancers improves the efficacy of combinational therapy targeting metabolism

6 October 2017

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6 October 2017

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AICAR-Induced Activation of AMPK Inhibits TSH/SREBP-2/HMGCR Pathway in Liver

6 October 2017

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The history of Autosomal Recessive Hypercholesterolemia (ARH). From clinical observations to gene identification

6 October 2017

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The Sirt1 activator SRT3025 provides atheroprotection in Apoe-/- mice by reducing hepatic Pcsk9 secretion and enhancing Ldlr expression

6 October 2017

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6 October 2017

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The NF-κB member p65 controls glutamine metabolism through miR-23a.

6 October 2017

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6 October 2017

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Low-density lipoprotein receptor (LDLR) family orchestrates cholesterol homeostasis

6 October 2017

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MEK5/ERK5 pathway: the first fifteen years

6 October 2017

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AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice

6 October 2017

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Oxidative phosphorylation induces de novo expression of the MHC class I in tumor cells through the ERK5 pathway.

6 October 2017

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Metabolic modulation of glioblastoma with dichloroacetate

6 October 2017

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6 October 2017

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Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer

6 October 2017

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Role of dichloroacetate in the treatment of genetic mitochondrial diseases

6 October 2017

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Combinatorial patterns of histone acetylations and methylations in the human genome

6 October 2017

1 reference

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ERK5 activates NF-kappaB in leukemic T cells and is essential for their growth in vivo.

6 October 2017

1 reference

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Inhibition of lipid synthesis through activation of AMP kinase: an additional mechanism for the hypolipidemic effects of berberine

6 October 2017

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Dichloroacetate causes toxic neuropathy in MELAS: a randomized, controlled clinical trial

6 October 2017

1 reference

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Phosphorylation of the acidic domain of Mdm2 by protein kinase CK2.

6 October 2017

1 reference

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Extracellular signal-regulated kinase-dependent stabilization of hepatic low-density lipoprotein receptor mRNA by herbal medicine berberine

6 October 2017

1 reference

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Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins

6 October 2017

1 reference

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Energy substrate modulates mitochondrial structure and oxidative capacity in cancer cells

6 October 2017

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ERK5 is a novel type of mitogen-activated protein kinase containing a transcriptional activation domain

6 October 2017

1 reference

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Big mitogen-activated kinase regulates multiple members of the MEF2 protein family

6 October 2017

1 reference

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Activation of the protein kinase ERK5/BMK1 by receptor tyrosine kinases. Identification and characterization of a signaling pathway to the nucleus

6 October 2017

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Interaction of myocyte enhancer factor 2 (MEF2) with a mitogen-activated protein kinase, ERK5/BMK1

6 October 2017

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BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2C

6 October 2017

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Regulation of rat liver hydroxymethylglutaryl coenzyme A reductase by a new class of noncompetitive inhibitors. Effects of dichloroacetate and related carboxylic acids on enzyme activity

6 October 2017

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The pharmacology of dichloroacetate

6 October 2017

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6 October 2017

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Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells

6 October 2017

1 reference

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Metabolic Effects of Sodium Dichloroacetate in Normal and Diabetic Dogs

6 October 2017

1 reference

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SUMOylation regulates the transcriptional activity of JunB in T lymphocytes.

6 October 2017

1 reference

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Metabolic Effects of Dichloroacetate in Patients with Diabetes Mellitus and Hyperlipoproteinemia

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5587676

Extracellular-signal-regulated kinase 5 modulates the antioxidant response by transcriptionally controlling Sirtuin 1 expression in leukemic cells.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5587676

p53 is activated in response to disruption of the pre-mRNA splicing machinery.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5587676

The effects of chylomicron remnants enriched in n-3 or n-6 polyunsaturated fatty acids on the transcription of genes regulating their uptake and metabolism by the liver: influence of cellular oxidative state

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5587676

Reduction of serum cholesterol in two patients with homozygous familial hypercholesterolemia by dichloroacetate

19 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FS41598-017-10339-5

inferred from DOI database lookup

7 January 2021

based on heuristic

Synthesis and structure-activity relationship of berberine analogues in LDLR up-regulation and AMPK activation

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FS41598-017-10339-5

inferred from DOI database lookup

7 January 2021

based on heuristic

Human hepatocyte culture

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28878225

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/S41598-017-10339-5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28878225%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

12 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28878225%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

PubMed publication ID

28878225

1 reference