The oncogenic role of the In1-ghrelin splicing variant in prostate cancer aggressiveness (Q41558039)

3 October 2017

The oncogenic role of the In1-ghrelin splicing variant in prostate cancer aggressiveness (English)

1 reference

3 October 2017

2

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11 June 2020

Enrique Gómez Gómez

4

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11 June 2020

Alejandro Ibáñez-Costa

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11 June 2020

María M Moreno

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11 June 2020

Michael D. Culler

16

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11 June 2020

Justo P. Castaño

18

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11 June 2020

Raul M Luque

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11 June 2020

12

Rosa Ortega-Salas

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11 June 2020

Daniel Hormaechea-Agulla

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11 June 2020

3

Juan M Jiménez-Vacas

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11 June 2020

7

Esther Rivero-Cortés

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11 June 2020

14

Natia Tsomaia

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11 June 2020

Julia Carrasco-Valiente

10

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11 June 2020

9

José Valero-Rosa

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11 June 2020

André Sarmento-Cabral

8

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André Sarmento-Cabral

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11 June 2020

author name string

Fernando L-López

6

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11 June 2020

Rafael Sánchez-Sánchez

11

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11 June 2020

Steve M Swanson

15

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11 June 2020

María J Requena

17

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11 June 2020

publication date

29 August 2017

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3 October 2017

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11 June 2020

volume

16

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11 June 2020

issue

1

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11 June 2020

page(s)

146

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describes a project that uses

11 June 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5576296/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1186/s12943-017-0713-9

0 references

cites work

Ghrelin O-acyltransferase (GOAT) enzyme is overexpressed in prostate cancer, and its levels are associated with patient's metabolic status: Potential value as a non-invasive biomarker.

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Is there an effect of ghrelin/ghrelin analogs on cancer? A systematic review

6 June 2018

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Multi-species sequence comparison reveals conservation of ghrelin gene-derived splice variants encoding a truncated ghrelin peptide.

6 June 2018

1 reference

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Presence of sst5TMD4, a truncated splice variant of the somatostatin receptor subtype 5, is associated to features of increased aggressiveness in pancreatic neuroendocrine tumors.

6 June 2018

1 reference

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Emerging mechanisms of resistance to androgen receptor inhibitors in prostate cancer

6 June 2018

1 reference

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Molecular Characterization of Growth Hormone-producing Tumors in the GC Rat Model of Acromegaly

6 June 2018

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In1-ghrelin, a splice variant of ghrelin gene, is associated with the evolution and aggressiveness of human neuroendocrine tumors: Evidence from clinical, cellular and molecular parameters

6 June 2018

1 reference

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In1-ghrelin splicing variant is overexpressed in pituitary adenomas and increases their aggressive features.

6 June 2018

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Diagnostic value of SFRP1 as a favorable predictive and prognostic biomarker in patients with prostate cancer

6 June 2018

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Truncated somatostatin receptor variant sst5TMD4 confers aggressive features (proliferation, invasion and reduced octreotide response) to somatotropinomas

6 June 2018

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6 June 2018

Cancer statistics, 2015

1 reference

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Remodeling of channel-forming ORAI proteins determines an oncogenic switch in prostate cancer

6 June 2018

1 reference

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Ghrelin gene products, receptors, and GOAT enzyme: biological and pathophysiological insight.

6 June 2018

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Response of the insulin-like growth factor (IGF) system to IGF-IR inhibition and androgen deprivation in a neoadjuvant prostate cancer trial: effects of obesity and androgen deprivation

6 June 2018

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Cloning of a novel insulin-regulated ghrelin transcript in prostate cancer.

6 June 2018

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6 June 2018

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Promiscuous dimerization of the growth hormone secretagogue receptor (GHS-R1a) attenuates ghrelin-mediated signaling

6 June 2018

1 reference

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Modulation of ghrelin axis influences the growth of colonic and prostatic cancer cells in vitro

6 June 2018

1 reference

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The ghrelin axis--does it have an appetite for cancer progression?

6 June 2018

1 reference

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The rationale for targeting the LOX family in cancer

6 June 2018

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Lysyl oxidase, extracellular matrix remodeling and cancer metastasis

6 June 2018

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The new truncated somatostatin receptor variant sst5TMD4 is associated to poor prognosis in breast cancer and increases malignancy in MCF-7 cells

6 June 2018

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Ghrelin acylation and metabolic control

6 June 2018

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A novel human ghrelin variant (In1-ghrelin) and ghrelin-O-acyltransferase are overexpressed in breast cancer: potential pathophysiological relevance

6 June 2018

1 reference

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Purification and direct transformation of epithelial progenitor cells from primary human prostate

6 June 2018

1 reference

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Ghrelin inhibits proliferation and increases T-type Ca2+ channel expression in PC-3 human prostate carcinoma cells

6 June 2018

1 reference

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Increased expression of androgen receptor sensitizes prostate cancer cells to low levels of androgens.

6 June 2018

1 reference

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New insights into the molecular complexity of the ghrelin gene locus

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576296

Nuclear receptor interaction protein, a coactivator of androgen receptors (AR), is regulated by AR and Sp1 to feed forward and activate its own gene expression through AR protein stability

6 June 2018

1 reference

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Adenomatous polyposis coli (APC): a multi-functional tumor suppressor gene

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576296

Prognostic value of p16 in locally advanced prostate cancer: a study based on Radiation Therapy Oncology Group Protocol 9202.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576296

Androgens induce increases in intracellular calcium via a G protein-coupled receptor in LNCaP prostate cancer cells

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576296

Ghrelin and a novel preproghrelin isoform are highly expressed in prostate cancer and ghrelin activates mitogen-activated protein kinase in prostate cancer

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576296

Expression of ghrelin and biological activity of specific receptors for ghrelin and des-acyl ghrelin in human prostate neoplasms and related cell lines

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576296

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576296

Expression and action of the growth hormone releasing peptide ghrelin and its receptor in prostate cancer cell lines

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576296

Castration-induced up-regulation of insulin-like growth factor binding protein-5 potentiates insulin-like growth factor-I activity and accelerates progression to androgen independence in prostate cancer models

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576296

Ghrelin is a growth-hormone-releasing acylated peptide from stomach

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576296

Insulin-like growth factor-I (IGF-I) and IGF binding protein-3 as predictors of advanced-stage prostate cancer.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5576296

Complete Response to the Combination Therapy with Androgen Blockade and Somatostatin Analogue in a Patient with Advanced Prostate Cancer: Magnetic Resonance Imaging with 1H-Spectroscopy

19 August 2018

1 reference

12 December 2020

Overexpression of insulin-like growth factor binding protein-5 helps accelerate progression to androgen-independence in the human prostate LNCaP tumor model through activation of phosphatidylinositol 3'-kinase pathway

1 reference

12 December 2020

Insulin Increases De Novo Steroidogenesis in Prostate Cancer Cells

1 reference

12 December 2020

Androgens increase intracellular calcium concentration and inositol 1,4,5-trisphosphate and diacylglycerol formation via a pertussis toxin-sensitive G-protein

1 reference

12 December 2020

10.1186/S12943-017-0713-9

Identifiers

DOI

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11 June 2020

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11 June 2020

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