Communication between the extracellular environment, cytoplasmic signalling cascades and the nuclear cell-cycle machinery (Q41553984)

3 October 2017

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title

Communication between the extracellular environment, cytoplasmic signalling cascades and the nuclear cell-cycle machinery (English)

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3 October 2017

2

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3 October 2017

Peeper DS

1

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PubMed ID

9247113

3 October 2017

language of work or name

English

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publication date

1 June 1997

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3 October 2017

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3 October 2017

410

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3 October 2017

1

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3 October 2017

11-16

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G1 events and regulation of cell proliferation

3 October 2017

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

The retinoblastoma protein and cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Adenovirus-E1A proteins transform cells by sequestering regulatory proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Growth inhibition by TGF-beta linked to suppression of retinoblastoma protein phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

TGF-beta 1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Growth-regulated expression of D-type cyclin genes in human diploid fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Functional interactions of the retinoblastoma protein with mammalian D-type cyclins

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Physical interaction of the retinoblastoma protein with human D cyclins

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Cyclin D1 is a nuclear protein required for cell cycle progression in G1

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Function of a human cyclin gene as an oncogene

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

TGF beta inhibition of Cdk4 synthesis is linked to cell cycle arrest

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Cyclin D1 provides a link between development and oncogenesis in the retina and breast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Requirement for tyrosine phosphorylation of Cdk4 in G1 arrest induced by ultraviolet irradiation

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Elevated levels of cyclin D1 protein in response to increased expression of eukaryotic initiation factor 4E

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Inhibitors of mammalian G1 cyclin-dependent kinases

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Functional analysis of the transforming growth factor beta responsive elements in the WAF1/Cip1/p21 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase 4 activation.

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Requirement of p27Kip1 for restriction point control of the fibroblast cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Transformation of NIH 3T3 cells by microinjection of Ha-ras p21 protein

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Characterization of G1 transit induced by the mitogenic-oncogenic viral Ki-ras gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Cellular ras activity is required for passage through multiple points of the G0/G1 phase in BALB/c 3T3 cells

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Cell cycle-dependent activation of Ras.

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Inhibition by cAMP of Ras-dependent activation of Raf.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progression in NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Inactivation of a Cdk2 inhibitor during interleukin 2-induced proliferation of human T lymphocytes

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP.

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Effect of a dominant inhibitory Ha-ras mutation on mitogenic signal transduction in NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Growth suppression by p16ink4 requires functional retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Inhibition of ras-induced proliferation and cellular transformation by p16INK4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

TGF beta-induced growth inhibition in primary fibroblasts requires the retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Involvement of p21ras in activation of extracellular signal-regulated kinase 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Phosphatidylinositol-3-OH kinase as a direct target of Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

KSR: a novel player in the RAS pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Oncogenic Ras activates c-Jun via a separate pathway from the activation of extracellular signal-regulated kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

A role for Rho in Ras transformation

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

An essential role for Rac in Ras transformation

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Inhibition of Ras-induced DNA synthesis by expression of the phosphatase MKP-1.

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Multiple Ras functions can contribute to mammalian cell transformation

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Interleukin-2 triggers a novel phosphatidylinositol 3-kinase-dependent MEK activation pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Activation of pp70/85 S6 kinases in interleukin-2-responsive lymphoid cells is mediated by phosphatidylinositol 3-kinase and inhibited by cyclic AMP.

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Activation of p70/p85 S6 kinase by a pathway independent of p21ras

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

A mammalian protein targeted by G1-arresting rapamycin-receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Rapamycin resistance tied to defective regulation of p27Kip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Raf1 interaction with Cdc25 phosphatase ties mitogenic signal transduction to cell cycle activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

CDC25 phosphatases as potential human oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Role of the INK4a locus in tumor suppression and cell mortality.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Transformation suppressor activity of a Jun transcription factor lacking its activation domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Mitogenic signaling by colony-stimulating factor 1 and ras is suppressed by the ets-2 DNA-binding domain and restored by myc overexpression

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Transformation and transactivation suppressor activity of the c-Jun leucine zipper fused to a bacterial repressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Myc but not Fos rescue of PDGF signalling block caused by kinase-inactive Src.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Cyclin D1 expression is regulated by the retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Growth factor regulation of cyclin D1 mRNA expression through protein synthesis-dependent and -independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Cdc25 cell-cycle phosphatase as a target of c-myc

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Cyclin D1 is dispensable for G1 control in retinoblastoma gene-deficient cells independently of cdk4 activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Distinct roles for cyclin-dependent kinases in cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Human cyclin E, a nuclear protein essential for the G1-to-S phase transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Regulation of the cyclin E gene by transcription factor E2F1

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes

21 January 2018

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

E2F-induced S phase requires cyclin E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Developmental control of the G1 to S transition in Drosophila: cyclin Eis a limiting downstream target of E2F

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Differential effects of cdk2 and cdk3 on the control of pRb and E2F function during G1 exit

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

p70s6k function is essential for G1 progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

21 January 2018

Tumor suppressor genes

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https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

p53-dependent repression of CDK4 translation in TGF-beta-induced G1 cell-cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Fibrillar collagen inhibits arterial smooth muscle proliferation through regulation of Cdk2 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

The adenovirus E1A protein overrides the requirement for cellular ras in initiating DNA synthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

Activation of the phosphatase activity of human cdc25A by a cdk2-cyclin E dependent phosphorylation at the G1/S transition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2897%2900319-0

10.1016/S0014-5793(97)00319-0

7 January 2021

Identifiers

DOI

1 reference

3 October 2017

1 reference

PubMed ID

9247113