Structural insights into substrate traffic and inhibition in acetylcholinesterase (Q41444745)

30 September 2017

Structural insights into substrate traffic and inhibition in acetylcholinesterase (English)

1 reference

30 September 2017

Martin Weik

8

0 references

Joel L. Sussman

object named as

Joel L Sussman

5

0 references

author name string

Jacques-Philippe Colletier

1

1 reference

30 September 2017

Didier Fournier

2

1 reference

30 September 2017

Harry M Greenblatt

3

1 reference

30 September 2017

Jure Stojan

4

1 reference

30 September 2017

Giuseppe Zaccai

6

1 reference

30 September 2017

Israel Silman

7

1 reference

30 September 2017

language of work or name

English

0 references

publication date

8 June 2006

1 reference

30 September 2017

1 reference

30 September 2017

25

1 reference

30 September 2017

12

1 reference

30 September 2017

2746-2756

1 reference

Acetylcholinesterase: 'classical' and 'non-classical' functions and pharmacology

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

Coot: model-building tools for molecular graphics

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

Refinement of macromolecular structures by the maximum-likelihood method

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

Detection, delineation, measurement and display of cavities in macromolecular structures

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

The CCP4 suite: programs for protein crystallography

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

PRODRG: a tool for high-throughput crystallography of protein-ligand complexes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

Acetylcholinesterase: a multifaceted target for structure-based drug design of anticholinesterase agents for the treatment of Alzheimer's disease

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

A new and rapid colorimetric determination of acetylcholinesterase activity

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

Crystal structure of human butyrylcholinesterase and of its complexes with substrate and products

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

Structure of a complex of the potent and specific inhibitor BW284C51 with Torpedo californica acetylcholinesterase

1 October 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

1 October 2017

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7601175

Structures of recombinant native and E202Q mutant human acetylcholinesterase complexed with the snake-venom toxin fasciculin-II

21 January 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

1 October 2017

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7601175

Three-dimensional structures ofDrosophila melanogasteracetylcholinesterase and of its complexes with two potent inhibitors

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

Crystal structures of aged phosphonylated acetylcholinesterase: nerve agent reaction products at the atomic level

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

Crystal structure of an acetylcholinesterase-fasciculin complex: interaction of a three-fingered toxin from snake venom with its target

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

Miniature endplate current rise times less than 100 microseconds from improved dual recordings can be modeled with passive acetylcholine diffusion from a synaptic vesicle

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

Acetylcholinesterase inhibition by fasciculin: crystal structure of the complex

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

An electrostatic mechanism for substrate guidance down the aromatic gorge of acetylcholinesterase

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

Mutagenesis of essential functional residues in acetylcholinesterase

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

Atomic Structure of Acetylcholinesterase from Torpedo californica : A Prototypic Acetylcholine-Binding Protein

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

Substrate inhibition of acetylcholinesterase: residues affecting signal transduction from the surface to the catalytic center

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

Expression of recombinant acetylcholinesterase in a baculovirus system: kinetic properties of glutamate 199 mutants

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

Interaction of fluorescence probes with acetylcholinesterase. Site and specificity of propidium binding

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

Electrostatic influence on the kinetics of ligand binding to acetylcholinesterase. Distinctions between active center ligands and fasciculin

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

Site of fasciculin interaction with acetylcholinesterase

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

Acetylcholinesterase peripheral anionic site degeneracy conferred by amino acid arrays sharing a common core.

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

Role of the peripheral anionic site on acetylcholinesterase: inhibition by substrates and coumarin derivatives

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

A mechanistic model for butyrylcholinesterase

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

11 June 2018

Acetylcholinesterase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

Inhibition of Drosophila melanogaster acetylcholinesterase by high concentrations of substrate

11 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

Unmasking Tandem Site Interaction in Human Acetylcholinesterase. Substrate Activation with a Cationic Acetanilide Substrate

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

Vesicle size and transmitter release at the frog neuromuscular junction when quantal acetylcholine content is increased or decreased

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

Histochemical method for characterization of enzyme crystals: application to crystals of Torpedo californica acetylcholinesterase.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

Involvement of deacylation in activation of substrate hydrolysis by Drosophila acetylcholinesterase

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

Carbonyl-carbonyl interactions stabilize the partially allowed Ramachandran conformations of asparagine and aspartic acid.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

External and internal electrostatic potentials of cholinesterase models.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

Two invertebrate acetylcholinesterases show activation followed by inhibition with substrate concentration

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1500847

Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants

19 August 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7601175

PROCHECK: a program to check the stereochemical quality of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7601175

Acetylcholinesterase: enzyme structure, reaction dynamics, and virtual transition states

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7601175

The X-ray Structure of a Transition State Analog Complex Reveals the Molecular Origins of the Catalytic Power and Substrate Specificity of Acetylcholinesterase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7601175

Fasciculin 2 binds to the peripheral site on acetylcholinesterase and inhibits substrate hydrolysis by slowing a step involving proton transfer during enzyme acylation

21 January 2018

1 reference

12 December 2020

Responses of acetylcholinesterase from Torpedo marmorata to salts and curarizing drugs

1 reference

12 December 2020

Interaction of quaternary ammonium compounds with acetylcholinesterase: characterization of the active site

1 reference

12 December 2020

Purification and crystallization of a dimeric form of acetylcholinesterase from Torpedo californica subsequent to solubilization with phosphatidylinositol-specific phospholipase C

1 reference

12 December 2020

A steric blockade model for inhibition of acetylcholinesterase by peripheral site ligands and substrate

1 reference

12 December 2020

Kinetic effects of leptocurares and pachycurares on the methanesulfonylation of acetylcholinesterase. A correlation with pharmacodynamic properties

1 reference

12 December 2020

The inhibitory effect of stilbamidine, curare and related compounds and its relationship to the active groups of acetylcholine esterase; action of stilbamidine upon nerve impulse conduction

1 reference

12 December 2020

CHOLINESTERASE INHIBITION IN SPIDER MITES SUSCEPTIBLE AND RESISTANT TO ORGANOPHOSPHATE

1 reference

12 December 2020

Differential effects of "peripheral" site ligands on Torpedo and chicken acetylcholinesterase

1 reference

12 December 2020

Relative binding sites of pharmacologically active ligands on bovine erythrocyte acetylcholinesterase

1 reference

12 December 2020

Asp7O in the peripheral anionic site of human butyrylcholinesterase

1 reference

12 December 2020

Nonequilibrium analysis alters the mechanistic interpretation of inhibition of acetylcholinesterase by peripheral site ligands

1 reference

12 December 2020

Mechanism of hydrolysis. II. New evidence for an acylated enzyme as intermediate

1 reference

12 December 2020

Carbonyl–Carbonyl Interactions can be Competitive with Hydrogen Bonds

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7601175

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/SJ.EMBOJ.7601175

1 reference

30 September 2017

1 reference

30 September 2017

1 reference