A steric blockade model for inhibition of acetylcholinesterase by peripheral site ligands and substrate (Q78044728)

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10 December 2019

title

A steric blockade model for inhibition of acetylcholinesterase by peripheral site ligands and substrate (English)

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10 December 2019

author name string

T L Rosenberry

1

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10 December 2019

W D Mallender

2

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10 December 2019

P J Thomas

3

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10 December 2019

T Szegletes

4

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10 December 2019

publication date

1 May 1999

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Chemico-biological Interactions

10 December 2019

published in

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10 December 2019

volume

119-120

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10 December 2019

page(s)

85-97

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Interaction of fluorescence probes with acetylcholinesterase. Site and specificity of propidium binding

10 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900017-4

Nonequilibrium analysis alters the mechanistic interpretation of inhibition of acetylcholinesterase by peripheral site ligands

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900017-4

Fasciculin 2 binds to the peripheral site on acetylcholinesterase and inhibits substrate hydrolysis by slowing a step involving proton transfer during enzyme acylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900017-4

Substrate binding to the peripheral site of acetylcholinesterase initiates enzymatic catalysis. Substrate inhibition arises as a secondary effect

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900017-4

Spectrophotometric study of the acetylcholinesterase-catalyzed hydrolysis of 1-methyl-acetoxyquinolinium iodides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900017-4

Catalysis by acetylcholinesterase. Synergistic effects of inhibitors during the hydrolysis of acetic acid esters

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900017-4

Acetylcholinesterase. Two types of inhibition by an organophosphorus compound: one the formation of phosphorylated enzyme and the other analogous to inhibition by substrate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900017-4

Quantitative simulation of endplate currents at neuromuscular junctions based on the reaction of acetylcholine with acetylcholine receptor and acetylcholinesterase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900017-4

Binding of the neurotoxin fasciculin 2 to the acetylcholinesterase peripheral site drastically reduces the association and dissociation rate constants for N-methylacridinium binding to the active site

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900017-4

Organophosphorylation of acetylcholinesterase in the presence of peripheral site ligands. Distinct effects of propidium and fasciculin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2899%2900017-4

10.1016/S0009-2797(99)00017-4

7 January 2021

Identifiers

DOI

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10 December 2019

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