ITIMs and ITAMs. The Yin and Yang of antigen and Fc receptor-linked signaling machinery (Q41361358)

29 September 2017

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title

ITIMs and ITAMs. The Yin and Yang of antigen and Fc receptor-linked signaling machinery (English)

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29 September 2017

Isakov N

1

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29 September 2017

1 February 1997

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29 September 2017

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29 September 2017

16

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29 September 2017

1

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29 September 2017

85-100

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https://scigraph.springernature.com/pub.10.1007/bf02786325

29 September 2017

0 references

1 reference

https://api.crossref.org/works/10.1007%2FBF02786325

A requirement for Syk in the activation of the microtubule-associated protein kinase/phospholipase A2 pathway by Fc epsilon R1 is not shared by a G protein-coupled receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02786325

Interactions of p59fyn and ZAP-70 with T-cell receptor activation motifs: defining the nature of a signalling motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02786325

Syk is activated by phosphotyrosine-containing peptides representing the tyrosine-based activation motifs of the high affinity receptor for IgE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02786325

Syk protein-tyrosine kinase is regulated by tyrosine-phosphorylated Ig alpha/Ig beta immunoreceptor tyrosine activation motif binding and autophosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02786325

Binding of ZAP-70 to phosphorylated T-cell receptor zeta and eta enhances its autophosphorylation and generates specific binding sites for SH2 domain-containing proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02786325

F2(Pmp)2-TAM zeta 3, a novel competitive inhibitor of the binding of ZAP-70 to the T cell antigen receptor, blocks early T cell signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02786325

Characterization of hematopoietic intracellular protein tyrosine phosphatases: description of a phosphatase containing an SH2 domain and another enriched in proline-, glutamic acid-, serine-, and threonine-rich sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02786325

Association of hematopoietic cell phosphatase with c-Kit after stimulation with c-Kit ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02786325

Hematopoietic cell phosphatase associates with the interleukin-3 (IL-3) receptor beta chain and down-regulates IL-3-induced tyrosine phosphorylation and mitogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02786325

Structure and expression of human IgG FcRII(CD32). Functional heterogeneity is encoded by the alternatively spliced products of multiple genes

21 January 2018

1 reference

12 December 2020

Identification of signaling motifs within human Fc gamma RIIa and Fc gamma RIIb isoforms

1 reference

12 December 2020

The T cell receptor/CD3 complex: a dynamic protein ensemble

1 reference

12 December 2020

Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk

1 reference

12 December 2020

Molecular cloning of a porcine gene syk that encodes a 72-kDa protein-tyrosine kinase showing high susceptibility to proteolysis

1 reference

12 December 2020

Isolation of a src homology 2-containing tyrosine phosphatase

1 reference

12 December 2020

Antigen activation of murine T cells induces tyrosine phosphorylation of a polypeptide associated with the T cell antigen receptor

1 reference

12 December 2020

A role in B cell activation for CD22 and the protein tyrosine phosphatase SHP

1 reference

12 December 2020

"Viable motheaten," a new allele at the motheaten locus. I. Pathology

1 reference

12 December 2020

Activation of T cells by a tyrosine kinase activation domain in the cytoplasmic tail of CD3 epsilon.

1 reference

12 December 2020

Sequence requirements for induction of cytolysis by the T cell antigen/Fc receptor zeta chain

1 reference

12 December 2020

The B lymphocyte calcium response to anti-Ig is diminished by membrane immunoglobulin cross-linkage to the Fc gamma receptor.

1 reference

12 December 2020

Reconstitution of T cell receptor zeta-mediated calcium mobilization in nonlymphoid cells.

1 reference

12 December 2020

The cytoplasmic domain of the T cell receptor zeta chain is sufficient to couple to receptor-associated signal transduction pathways

1 reference

12 December 2020

Activation of a phosphotyrosine phosphatase by tyrosine phosphorylation

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12 December 2020

A 13-amino-acid motif in the cytoplasmic domain of FcγRIIB modulates B-cell receptor signalling

1 reference

12 December 2020

Syk tyrosine kinase required for mouse viability and B-cell development

1 reference

12 December 2020

Induction of tumor necrosis factor-alpha production by mast cells via Fc gamma R. Role of the Fc gamma RIII gamma subunit

1 reference

12 December 2020

Protein tyrosine phosphatase 1C negatively regulates antigen receptor signaling in B lymphocytes and determines thresholds for negative selection.

1 reference

12 December 2020

Signal transduction by immunoglobulin is mediated through Ig alpha and Ig beta

1 reference

12 December 2020

Phenotypic and functional effects of the motheaten gene on murine B and T lymphocytes

1 reference

12 December 2020

Activating and inhibitory mutations in adjacent tyrosines in the kinase domain of ZAP-70.

1 reference

12 December 2020

Inhibition of mast cell Fc epsilon R1-mediated signaling and effector function by the Syk-selective inhibitor, piceatannol.

1 reference

12 December 2020

Purification and characterization of human ZAP-70 protein-tyrosine kinase from a baculovirus expression system

1 reference

12 December 2020

Potent stimulation of SH-PTP2 phosphatase activity by simultaneous occupancy of both SH2 domains

1 reference

12 December 2020

TCR activation of ZAP70 is impaired in CD4+CD8+ thymocytes as a consequence of intrathymic interactions that diminish available p56lck

1 reference

12 December 2020

Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists

1 reference

12 December 2020

Expression and catalytic activity of the tyrosine phosphatase PTP1C is severely impaired in motheaten and viable motheaten mice

1 reference

12 December 2020

Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase

1 reference

12 December 2020

Different patterns of calcium signaling triggered through two components of the B lymphocyte antigen receptor

1 reference

12 December 2020

Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases

1 reference

12 December 2020

Murine recombinant Fc gamma RIII, but not Fc gamma RII, trigger serotonin release in rat basophilic leukemia cells.

1 reference

12 December 2020

Association of the 72-kDa protein-tyrosine kinase PTK72 with the B cell antigen receptor

1 reference

12 December 2020

The zeta chain is associated with a tyrosine kinase and upon T-cell antigen receptor stimulation associates with ZAP-70, a 70-kDa tyrosine phosphoprotein

1 reference

12 December 2020

Recruitment and activation of PTP1C in negative regulation of antigen receptor signaling by Fc gamma RIIB1.

1 reference

12 December 2020

The coordinated action of protein tyrosine phosphatases and kinases in cell signaling

1 reference

12 December 2020

A protein-tyrosine phosphatase with sequence similarity to the SH2 domain of the protein-tyrosine kinases

1 reference

12 December 2020

Distinct functions of the Fc epsilon R1 gamma and beta subunits in the control of Fc epsilon R1-mediated tyrosine kinase activation and signaling responses in RBL-2H3 mast cells.

1 reference

12 December 2020

Activation of immune system effector function by T-cell or Fc receptor intracellular domains

1 reference

12 December 2020

The implications of subunit interactions for the structure of the T cell receptor-CD3 complex

1 reference

12 December 2020

B lymphocyte activation is accompanied by phosphorylation of a 72-kDa protein-tyrosine kinase

1 reference

12 December 2020

Essential role for ZAP-70 in both positive and negative selection of thymocytes

1 reference

12 December 2020

The mouse mutant "motheaten." II. Functional studies of the immune system

1 reference

12 December 2020

T cell antigen receptor phosphorylation induced by an anti-receptor antibody

1 reference

12 December 2020

T cell antigen receptor signal transduction: a tale of tails and cytoplasmic protein-tyrosine kinases

1 reference

12 December 2020

Fc gamma RII expression in resting and activated B lymphocytes

1 reference

12 December 2020

T cell activation by clustered tyrosine kinases

1 reference

12 December 2020

The B-cell antigen receptor complex: structure and signal transduction

1 reference

12 December 2020

Defective T cell receptor signaling and CD8+ thymic selection in humans lacking zap-70 kinase

1 reference

12 December 2020

The B-cell antigen receptor complex

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12 December 2020

Mammalian SH2-containing protein tyrosine phosphatases.

1 reference

12 December 2020

Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene.

1 reference

12 December 2020

The mouse mutant "motheaten". I. Development of lymphocyte populations

1 reference

12 December 2020

ZAP-70 is constitutively associated with tyrosine-phosphorylated TCR zeta in murine thymocytes and lymph node T cells

1 reference

12 December 2020

Cytoplasmic domain heterogeneity and functions of IgG Fc receptors in B lymphocytes

1 reference

12 December 2020

Assembly and function of the T cell antigen receptor. Requirement of either the lysine or arginine residues in the transmembrane region of the alpha chain

1 reference

12 December 2020

Recruitment of tyrosine phosphatase HCP by the killer cell inhibitor receptor

1 reference

12 December 2020

Crosslinking of surface immunoglobulin and Fc receptors on B lymphocytes inhibits stimulation of inositol phospholipid breakdown via the antigen receptors

1 reference

12 December 2020

ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain

1 reference

12 December 2020

Human and mouse killer-cell inhibitory receptors recruit PTP1C and PTP1D protein tyrosine phosphatases

1 reference

12 December 2020

ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency

1 reference

12 December 2020

Dual role of the tyrosine activation motif of the Ig-alpha protein during signal transduction via the B cell antigen receptor

1 reference

12 December 2020

Motheaten, an immunodeficient mutant of the mouse. II. Depressed immune competence and elevated serum immunoglobulins

1 reference

12 December 2020

Regulation of high-affinity IgE receptor-mediated mast cell activation by murine low-affinity IgG receptors.

1 reference

12 December 2020

Interactions of TCR tyrosine based activation motifs with tyrosine kinases.

1 reference

12 December 2020

Fc-dependent inhibition of mouse B cell activation by whole anti-mu antibodies

1 reference

12 December 2020

Identification of the tyrosine phosphatase PTP1C as a B cell antigen receptor-associated protein involved in the regulation of B cell signaling

1 reference

12 December 2020

Activation of the SH2-containing phosphotyrosine phosphatase SH-PTP2 by its binding site, phosphotyrosine 1009, on the human platelet-derived growth factor receptor

1 reference

12 December 2020

The tyrosine activation motif as a target of protein tyrosine kinases and SH2 domains

1 reference

12 December 2020

The B cell antigen receptor complex: association of Ig-alpha and Ig-beta with distinct cytoplasmic effectors

1 reference

12 December 2020

Activation of ZAP-70 kinase activity by phosphorylation of tyrosine 493 is required for lymphocyte antigen receptor function

1 reference

12 December 2020

New nomenclature for the Reth motif (or ARH1/TAM/ARAM/YXXL)

1 reference

12 December 2020

Delineation of a T-cell activation motif required for binding of protein tyrosine kinases containing tandem SH2 domains

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12 December 2020

The T cell antigen receptor zeta chain is tyrosine phosphorylated upon activation.

1 reference

12 December 2020

The same tyrosine-based inhibition motif, in the intra-cytoplasmic domain of FcγRIIB, regulates negatively BCR-, TCR-, and FcR-dependent cell activation

1 reference

12 December 2020

Antigen receptor tail clue.

1 reference

12 December 2020

The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules.

1 reference

12 December 2020

Molecular basis for interaction of the protein tyrosine kinase ZAP-70 with the T-cell receptor

1 reference

12 December 2020

Differential signaling through the Ig-alpha and Ig-beta components of the B cell antigen receptor

1 reference

12 December 2020

Phosphorylation/dephosphorylation of high-affinity IgE receptors: a mechanism for coupling/uncoupling a large signaling complex

1 reference

12 December 2020

Tyrosine phosphorylation and dephosphorylation in T lymphocyte activation

1 reference

12 December 2020

Tandem SH2 domains of ZAP-70 bind to T cell antigen receptor zeta and CD3 epsilon from activated Jurkat T cells

1 reference

12 December 2020

Cross-linking of IgG receptors inhibits membrane immunoglobulin-stimulated calcium influx in B lymphocytes

1 reference

12 December 2020

Association of IgA-Fc receptors (Fc alpha R) with Fc epsilon RI gamma 2 subunits in U937 cells. Aggregation induces the tyrosine phosphorylation of gamma 2

1 reference

12 December 2020

Molecular basis of Fc receptor function

1 reference

12 December 2020

Requirements for mitogenic stimulation of murine B cells by soluble anti-IgM antibodies

1 reference

12 December 2020

Role of associated gamma-chain in tyrosine kinase activation via murine Fc gamma RIII

1 reference

12 December 2020

Use of an oriented peptide library to determine the optimal substrates of protein kinases

1 reference

12 December 2020

Antigen and Fc receptor signaling. The awesome power of the immunoreceptor tyrosine-based activation motif (ITAM).

1 reference

12 December 2020

Motheaten and viable motheaten mice have mutations in the haematopoietic cell phosphatase gene

1 reference

12 December 2020

Analysis of the interaction of ZAP-70 and syk protein-tyrosine kinases with the T-cell antigen receptor by plasmon resonance

1 reference

12 December 2020

T-cell and basophil activation through the cytoplasmic tail of T-cell-receptor zeta family proteins.

1 reference

12 December 2020

Hematopoietic cell phosphatase associates with erythropoietin (Epo) receptor after Epo-induced receptor tyrosine phosphorylation: identification of potential binding sites

1 reference

12 December 2020

Antigen receptors on B lymphocytes

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12 December 2020

Functional characterization of a signal transducing motif present in the T cell antigen receptor zeta chain

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12 December 2020

Tyrosine phosphorylation of components of the B-cell antigen receptors following receptor crosslinking

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12 December 2020

Cellular immunity to HIV activated by CD4 fused to T cell or Fc receptor polypeptides

1 reference

12 December 2020

ZAP-70 binding specificity to T cell receptor tyrosine-based activation motifs: the tandem SH2 domains of ZAP-70 bind distinct tyrosine-based activation motifs with varying affinity

1 reference

12 December 2020

Tyrosine kinases and tyrosine-based activation motifs. Current research on activation via the T cell antigen receptor

1 reference

12 December 2020

Tyrosine kinases Lyn and Syk regulate B cell receptor-coupled Ca2+ mobilization through distinct pathways

1 reference

12 December 2020

A tyrosine-phosphorylated 70-kDa protein binds a photoaffinity analogue of ATP and associates with both the zeta chain and CD3 components of the activated T cell antigen receptor

1 reference

12 December 2020

Functional analysis of human Fc gamma RII (CD32) isoforms expressed in B lymphocytes.

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF02786325

1 reference

PubMed ID

9048210

Dimensions Publication ID

29 September 2017

0 references

1 reference

PubMed ID

9048210