CLICs-dependent chloride efflux is an essential and proximal upstream event for NLRP3 inflammasome activation (Q41260378)

28 September 2017

CLICs-dependent chloride efflux is an essential and proximal upstream event for NLRP3 inflammasome activation (English)

1 reference

28 September 2017

1 reference

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28779175%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Tao Gong

5

1 reference

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8 June 2020

11

Rongbin Zhou

1 reference

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8 June 2020

author name string

Tiantian Tang

1

1 reference

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8 June 2020

Xueting Lang

2

1 reference

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8 June 2020

Xiaqiong Wang

4

1 reference

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8 June 2020

Yanqing Yang

6

1 reference

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8 June 2020

Jun Cui

7

1 reference

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8 June 2020

Li Bai

8

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8 June 2020

Jun Wang

9

1 reference

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8 June 2020

Wei Jiang

10

1 reference

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8 June 2020

language of work or name

English

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publication date

4 August 2017

1 reference

28 September 2017

Nature Communications

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8 June 2020

volume

8

1 reference

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8 June 2020

issue

1

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8 June 2020

page(s)

202

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Creative Commons Attribution 4.0 International

8 June 2020

copyright license

start time

4 August 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/s41467-017-00227-x

0 references

cites work

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Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models

1 October 2017

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Inflammasomes: mechanism of assembly, regulation and signalling

1 October 2017

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NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux

1 October 2017

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NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component

1 October 2017

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Caspase-11 Requires the Pannexin-1 Channel and the Purinergic P2X7 Pore to Mediate Pyroptosis and Endotoxic Shock

1 October 2017

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A Genome-wide CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) Screen Identifies NEK7 as an Essential Component of NLRP3 Inflammasome Activation

1 October 2017

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Molecular mechanisms regulating NLRP3 inflammasome activation

1 October 2017

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NLRP3 Inflammasome Is Expressed and Functional in Mouse Brain Microglia but Not in Astrocytes

1 October 2017

1 reference

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Members of the chloride intracellular ion channel protein family demonstrate glutaredoxin-like enzymatic activity.

1 October 2017

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1 October 2017

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K⁺ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter

1 October 2017

1 reference

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TRPM2 links oxidative stress to NLRP3 inflammasome activation

1 October 2017

1 reference

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NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice

1 October 2017

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The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP.

1 October 2017

1 reference

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Cell volume regulation modulates NLRP3 inflammasome activation

1 October 2017

1 reference

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Inflammasomes and their roles in health and disease

1 October 2017

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Critical role for calcium mobilization in activation of the NLRP3 inflammasome

1 October 2017

1 reference

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Inducible NOS-induced chloride intracellular channel 4 (CLIC4) nuclear translocation regulates macrophage deactivation.

1 October 2017

1 reference

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Rab25 and CLIC3 collaborate to promote integrin recycling from late endosomes/lysosomes and drive cancer progression.

1 October 2017

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Systemic delivery of siRNA with cationic lipid assisted PEG-PLA nanoparticles for cancer therapy

1 October 2017

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Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling

1 October 2017

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Role of CLIC4 in the host innate responses to bacterial lipopolysaccharide

1 October 2017

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The inflammasome NLRs in immunity, inflammation, and associated diseases

1 October 2017

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The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

1 October 2017

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A role for mitochondria in NLRP3 inflammasome activation

1 October 2017

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Chloride intracellular channel 1 functions in endothelial cell growth and migration

1 October 2017

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Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

1 October 2017

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The enigma of the CLIC proteins: Ion channels, redox proteins, enzymes, scaffolding proteins?

1 October 2017

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Thioredoxin-interacting protein links oxidative stress to inflammasome activation

1 October 2017

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Chloride intracellular channel-4 is a determinant of native collateral formation in skeletal muscle and brain

1 October 2017

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Functional reconstitution of mammalian 'chloride intracellular channels' CLIC1, CLIC4 and CLIC5 reveals differential regulation by cytoskeletal actin

1 October 2017

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Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration

1 October 2017

1 reference

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CLIC4 (p64H1) and its putative transmembrane domain form poorly selective, redox-regulated ion channels

1 October 2017

1 reference

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Gout-associated uric acid crystals activate the NALP3 inflammasome

1 October 2017

1 reference

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Redox regulation of CLIC1 by cysteine residues associated with the putative channel pore

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544706

Inhibitory effects of chloride on the activation of caspase-1, IL-1beta secretion, and cytolysis by the P2X7 receptor

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544706

Crystal structure of the soluble form of the redox-regulated chloride ion channel protein CLIC4.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544706

CLIC-5A functions as a chloride channel in vitro and associates with the cortical actin cytoskeleton in vitro and in vivo

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544706

The intracellular chloride ion channel protein CLIC1 undergoes a redox-controlled structural transition

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544706

Molecular physiology of P2X receptors

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544706

The nuclear chloride ion channel NCC27 is involved in regulation of the cell cycle

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544706

p53 and tumor necrosis factor alpha regulate the expression of a mitochondrial chloride channel protein

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544706

Molecular cloning and characterization of a mitogen-activated protein kinase-associated intracellular chloride channel

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544706

Intracellular chloride concentration influences the GABAA receptor subunit composition

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544706

CLIC-1 functions as a chloride channel when expressed and purified from bacteria

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544706

Innate immunity and inflammation.

14 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544706

Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544706

Omega-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544706

CLIC1 function is required for beta-amyloid-induced generation of reactive oxygen species by microglia.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544706

Selective role of intracellular chloride in the regulation of the intrinsic but not extrinsic pathway of apoptosis in Jurkat T-cells.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544706

CLIC1 inserts from the aqueous phase into phospholipid membranes, where it functions as an anion channel

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5544706

The organellular chloride channel protein CLIC4/mtCLIC translocates to the nucleus in response to cellular stress and accelerates apoptosis

19 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FS41467-017-00227-X

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7 January 2021

based on heuristic

Tenidap modulates cytoplasmic pH and inhibits anion transport in vitro. II. Inhibition of IL-1 beta production from ATP-treated monocytes and macrophages

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28779175

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/S41467-017-00227-X

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28779175%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

8 June 2020

ADS bibcode

2017NatCo...8..202T

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28779175%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

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