Development of nonnucleoside HIV reverse transcriptase inhibitors (Q41243158)

28 September 2017

1 reference

title

Development of nonnucleoside HIV reverse transcriptase inhibitors (English)

1 reference

28 September 2017

Tucker TJ

1

1 reference

28 September 2017

Lumma WC

series ordinal

2

1 reference

28 September 2017

Culberson JC

series ordinal

3

1 reference

28 September 2017

language of work or name

English

0 references

publication date

1 January 1996

1 reference

28 September 2017

Methods in Enzymology

1 reference

28 September 2017

275

1 reference

28 September 2017

440-472

1 reference

Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives

28 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975026-7

7 January 2021

2-Pyridinone derivatives: a new class of nonnucleoside, HIV-1-specific reverse transcriptase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975026-7

7 January 2021

Inhibition of HIV-1 Replication by a Nonnucleoside Reverse Transcriptase Inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975026-7

7 January 2021

A novel lead for specific anti-HIV-1 agents: 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975026-7

7 January 2021

5-chloro-3-(phenylsulfonyl)indole-2-carboxamide: a novel, non-nucleoside inhibitor of HIV-1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975026-7

7 January 2021

Identification of the human immunodeficiency virus reverse transcriptase residues that contribute to the activity of diverse nonnucleoside inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975026-7

7 January 2021

Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975026-7

7 January 2021

Natural occurrence of drug resistance mutations in the reverse transcriptase of human immunodeficiency virus type 1 isolates

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975026-7

7 January 2021

Fidelity of the RNA-dependent DNA synthesis exhibited by the reverse transcriptases of human immunodeficiency virus types 1 and 2 and of murine leukemia virus: mispair extension frequencies

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975026-7

7 January 2021

HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975026-7

7 January 2021

Non-nucleoside inhibitors of HIV-1 reverse transcriptase: molecular modeling and X-ray structure investigations

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975026-7

7 January 2021

Novel non-nucleoside inhibitors of HIV-1 reverse transcriptase. 1. Tricyclic pyridobenzo- and dipyridodiazepinones

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975026-7

7 January 2021

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975026-7

1 reference

7 January 2021

Synthesis and anti-HIV-1 activity of 4,5,6,7-tetrahydro-5-methylimidazo[4,5,1-jk][1,4]benzodiazepin- 2(1H)-one (TIBO) derivatives

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975026-7

7 January 2021

Synthesis and anti-HIV-1 activity of 4,5,6,7-tetrahydro-5-methylimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-on e (TIBO) derivatives. 2

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975026-7

7 January 2021

HIV-1-specific reverse transcriptase inhibitors show differential activity against HIV-1 mutant strains containing different amino acid substitutions in the reverse transcriptase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975026-7

7 January 2021

Pharmacokinetics of R 82913 in AIDS patients: a phase I dose-finding study of oral administration compared with intravenous infusion

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975026-7

7 January 2021

Synthesis and anti-HIV-1 activity of 4,5,6,7-tetrahydro-5-methylimidazo-[4,5,1-jk][1,4]benzodiazepin- 2(1H)-one (TlBO) derivatives. 4.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975026-7

7 January 2021

Synthesis and evaluation of 2-pyridinone derivatives as HIV-1-specific reverse transcriptase inhibitors. 2. Analogs of 3-aminopyridin-2(1H)-one

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975026-7

7 January 2021

Synthesis and evaluation of 2-pyridinone derivatives as HIV-1-specific reverse transcriptase inhibitors. 4. 3-[2-(Benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2(1H)-one and analogues

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975026-7

7 January 2021

Synthesis and evaluation of 2-pyridinone derivatives as specific HIV-1 reverse transcriptase inhibitors. 3. Pyridyl and phenyl analogs of 3-aminopyridin-2(1H)-one

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975026-7

7 January 2021

Synthesis and antiviral activity of deoxy analogs of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT) as potent and selective anti-HIV-1 agents

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975026-7

7 January 2021

Knocking-out concentrations of HIV-1-specific inhibitors completely suppress HIV-1 infection and prevent the emergence of drug-resistant virus.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975026-7

7 January 2021

Synthesis of a series of 4-(arylethynyl)-6-chloro-4-cyclopropyl-3,4-dihydroquinazolin-2(1H)-ones as novel non-nucleoside HIV-1 reverse transcriptase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975026-7

7 January 2021

L-743, 726 (DMP-266): a novel, highly potent nonnucleoside inhibitor of the human immunodeficiency virus type 1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975026-7

7 January 2021

Selective non-nucleoside HIV-1 reverse transcriptase inhibitors. New 2,3-dihydrothiazolo[2,3-a]isoindol-5(9bH)-ones and related compounds with anti-HIV-1 activity

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975026-7

7 January 2021

Synthesis and anti-HIV-1 activity of a series of imidazo[1,5-b]pyridazines

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975026-7

7 January 2021

Activity of a novel quinoxaline derivative against human immunodeficiency virus type 1 reverse transcriptase and viral replication

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975026-7

7 January 2021

Inhibition of reverse transcriptase of human immunodeficiency virus type 1 and chimeric enzymes of human immunodeficiency viruses types 1 and 2 by two novel non‐nucleoside inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975026-7

7 January 2021

Biological and biochemical anti-HIV activity of the benzothiadiazine class of nonnucleoside reverse transcriptase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975026-7

7 January 2021

Benzophenone derivatives: a novel series of potent and selective inhibitors of human immunodeficiency virus type 1 reverse transcriptase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975026-7

7 January 2021

High resolution structures of HIV-1 RT from four RT-inhibitor complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975026-7

7 January 2021

Resistance of clinical isolates of human immunodeficiency virus to antiretroviral agents

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2896%2975026-7

7 January 2021

10.1016/S0076-6879(96)75026-7

Identifiers

DOI

1 reference

28 September 2017

1 reference