Activity of a novel quinoxaline derivative against human immunodeficiency virus type 1 reverse transcriptase and viral replication (Q28368053)

1

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R Bender

2

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U M Billhardt

3

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C Meichsner

4

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G Riess

5

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M Rösner

6

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I Winkler

7

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A Paessens

Antimicrobial Agents and Chemotherapy

8

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language of work or name

English

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publication date

August 1993

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published in

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volume

37

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issue

8

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page(s)

1659-64

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cites work

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Chimeric human immunodeficiency virus type 1/type 2 reverse transcriptases display reversed sensitivity to nonnucleoside analog inhibitors

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Pyridinone derivatives: specific human immunodeficiency virus type 1 reverse transcriptase inhibitors with antiviral activity

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Functional analysis of HIV-1 reverse transcriptase amino acids involved in resistance to multiple nonnucleoside inhibitors

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Identification of the human immunodeficiency virus reverse transcriptase residues that contribute to the activity of diverse nonnucleoside inhibitors

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Resistance of human immunodeficiency virus type 1 reverse transcriptase to TIBO derivatives induced by site-directed mutagenesis

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20 March 2017

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20 March 2017

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A single conservative amino acid substitution in the reverse transcriptase of human immunodeficiency virus-1 confers resistance to (+)-(5S)-4,5,6,7-tetrahydro-5-methyl-6-(3-methyl-2-butenyl)imidazo[4,5, 1- jk][1,4]benzodiazepin-2(1H)-thione (TIBO R8

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Mutational analysis of two conserved sequence motifs in HIV-1 reverse transcriptase

2 June 2018

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27 November 2018

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