MRE11 stability is regulated by CK2-dependent interaction with R2TP complex (Q41151587)

27 September 2017

MRE11 stability is regulated by CK2-dependent interaction with R2TP complex (English)

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27 September 2017

1

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7 June 2020

Nicola O'Reilly

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7 June 2020

Stephen J Smerdon

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7 June 2020

Libor Macůrek

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7 June 2020

Zuzana Hořejší

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7 June 2020

author name string

K Burdova

2

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7 June 2020

T G Flower

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7 June 2020

S J Boulton

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7 June 2020

language of work or name

English

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publication date

24 April 2017

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27 September 2017

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7 June 2020

volume

36

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7 June 2020

issue

34

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7 June 2020

page(s)

4943-4950

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Creative Commons Attribution 4.0 International

7 June 2020

copyright license

start time

24 April 2017

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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exact match

https://scigraph.springernature.com/pub.10.1038/onc.2017.99

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cites work

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ATM-dependent phosphorylation of MRE11 controls extent of resection during homology directed repair by signalling through Exonuclease 1.

27 September 2017

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Sae2 promotes dsDNA endonuclease activity within Mre11-Rad50-Xrs2 to resect DNA breaks

27 September 2017

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Structural Basis for Phosphorylation-Dependent Recruitment of Tel2 to Hsp90 by Pih1

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Inositol pyrophosphates mediate the DNA-PK/ATM-p53 cell death pathway by regulating CK2 phosphorylation of Tti1/Tel2

27 September 2017

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Phosphorylation-dependent PIH1D1 interactions define substrate specificity of the R2TP cochaperone complex

27 September 2017

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Drosophila Spag is the homolog of RNA polymerase II-associated protein 3 (RPAP3) and recruits the heat shock proteins 70 and 90 (Hsp70 and Hsp90) during the assembly of cellular machineries

27 September 2017

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Suppression of DNA-damage checkpoint signaling by Rsk-mediated phosphorylation of Mre11.

27 September 2017

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Disease-associated MRE11 mutants impact ATM/ATR DNA damage signaling by distinct mechanisms

27 September 2017

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27 September 2017

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27 September 2017

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Mre11 regulates CtIP-dependent double-strand break repair by interaction with CDK2.

27 September 2017

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The MRE11 GAR motif regulates DNA double-strand break processing and ATR activation

27 September 2017

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27 September 2017

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HSP90 and its R2TP/Prefoldin-like cochaperone are involved in the cytoplasmic assembly of RNA polymerase II

27 September 2017

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CK2 phospho-dependent binding of R2TP complex to TEL2 is essential for mTOR and SMG1 stability

27 September 2017

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27 September 2017

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Limiting the persistence of a chromosome break diminishes its mutagenic potential

27 September 2017

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Aberrations of the MRE11-RAD50-NBS1 DNA damage sensor complex in human breast cancer: MRE11 as a candidate familial cancer-predisposing gene

27 September 2017

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A glycine-arginine domain in control of the human MRE11 DNA repair protein

27 September 2017

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Molecular chaperone Hsp90 stabilizes Pih1/Nop17 to maintain R2TP complex activity that regulates snoRNA accumulation

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Checkpoint failure and chromosomal instability without lymphomagenesis in Mre11(ATLD1/ATLD1) mice

27 September 2017

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The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder

27 September 2017

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The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks

27 September 2017

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Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome

27 September 2017

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Mre11 Is Essential for the Removal of Lethal Topoisomerase 2 Covalent Cleavage Complexes.

27 September 2017

1 reference

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I-SceI-based assays to examine distinct repair outcomes of mammalian chromosomal double strand breaks.

19 August 2018

1 reference

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HCLK2 is required for activity of the DNA damage response kinase ATR.

19 August 2018

1 reference

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19 August 2018

Identifiers

DOI

10.1038/ONC.2017.99

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28436950%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

7 June 2020

0 references

1 reference

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7 June 2020

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