Long-term silencing of retroviral vectors is resistant to reversal by trichostatin A and 5-azacytidine (Q40881551)

24 September 2017

Long-term silencing of retroviral vectors is resistant to reversal by trichostatin A and 5-azacytidine (English)

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24 September 2017

McInerney JM

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24 September 2017

Nawrocki JR

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2

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24 September 2017

Lowrey CH

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3

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24 September 2017

language of work or name

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1 April 2000

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24 September 2017

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24 September 2017

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24 September 2017

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24 September 2017

653-663

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https://scigraph.springernature.com/pub.10.1038/sj.gt.3301155

24 September 2017

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A stem cell-specific silencer in the primer-binding site of a retrovirus

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Characterization of the Moloney murine leukemia virus stem cell-specific repressor binding site

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Consistent, persistent expression from modified retroviral vectors in murine hematopoietic stem cells

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Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases

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Transcriptional silencing in yeast is associated with reduced nucleosome acetylation

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Efficient transcriptional silencing in Saccharomyces cerevisiae requires a heterochromatin histone acetylation pattern

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Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

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Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

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Trichostatin A causes selective loss of DNA methylation in Neurospora

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Treatment of mice with 5-azacytidine efficiently activates silent retroviral genomes in different tissues

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Transient and stable gene expression in mammalian cells transduced with a recombinant baculovirus vector

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Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation

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Histone acetyltransferase activity of yeast Gcn5p is required for the activation of target genes in vivo

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Loss of transcriptional activity of a transgene is accompanied by DNA methylation and histone deacetylation and is prevented by insulators

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Independent mechanisms involved in suppression of the Moloney leukemia virus genome during differentiation of murine teratocarcinoma cells

21 January 2018

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Gene silencing: repeats that count

21 January 2018

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Redesign of retrovirus packaging cell lines to avoid recombination leading to helper virus production

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Gene transfer into humans--immunotherapy of patients with advanced melanoma, using tumor-infiltrating lymphocytes modified by retroviral gene transduction

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Inactivation of the Moloney murine leukemia virus long terminal repeat in murine fibroblast cell lines is associated with methylation and dependent on its chromosomal position

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7 January 2021

Multiple modifications in cis elements of the long terminal repeat of retroviral vectors lead to increased expression and decreased DNA methylation in embryonic carcinoma cells.

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7 January 2021

The inactive X chromosome in female mammals is distinguished by a lack of histone H4 acetylation, a cytogenetic marker for gene expression

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7 January 2021

Increased probability of expression from modified retroviral vectors in embryonal stem cells and embryonal carcinoma cells

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7 January 2021

Brief report: treatment with azacitidine of patients with end-stage beta-thalassemia

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7 January 2021

A safe packaging line for gene transfer: separating viral genes on two different plasmids

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Identifiers

DOI

10.1038/SJ.GT.3301155

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Dimensions Publication ID

24 September 2017

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