Wild-type huntingtin protects from apoptosis upstream of caspase-3. (Q40880907)

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6 November 2019

title

Wild-type huntingtin protects from apoptosis upstream of caspase-3 (English)

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6 November 2019

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11

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6 November 2019

7

E Clementi

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6 November 2019

author name string

D Rigamonti

1

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6 November 2019

J H Bauer

2

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6 November 2019

C De-Fraja

3

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6 November 2019

L Conti

4

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6 November 2019

S Sipione

5

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6 November 2019

C Sciorati

6

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6 November 2019

A Hackam

8

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6 November 2019

M R Hayden

9

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6 November 2019

Y Li

10

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6 November 2019

C A Ross

12

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6 November 2019

S Govoni

13

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C Vincenz

14

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E Cattaneo

15

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language of work or name

English

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publication date

1 May 2000

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6 November 2019

published in

Journal of Neuroscience

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6 November 2019

volume

20

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6 November 2019

page(s)

3705-3713

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6 November 2019

issue

10

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Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarization

6 November 2019

cites work

1 reference

12 December 2020

Mutant huntingtin expression in clonal striatal cells: dissociation of inclusion formation and neuronal survival by caspase inhibition.

1 reference

12 December 2020

Huntington's disease: translating a CAG repeat into a pathogenic mechanism

1 reference

12 December 2020

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

1 reference

12 December 2020

Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease

1 reference

12 December 2020

Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract

1 reference

12 December 2020

Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes

1 reference

12 December 2020

Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansion

1 reference

12 December 2020

Non-virally mediated gene transfer into human central nervous system precursor cells.

1 reference

12 December 2020

Nuclear inclusions in glutamine repeat disorders: are they pernicious, coincidental, or beneficial?

1 reference

12 December 2020

Activation of the JAK/STAT pathway leads to proliferation of ST14A central nervous system progenitor cells

1 reference

12 December 2020

Survival, integration, and differentiation of neural stem cell lines after transplantation to the adult rat striatum

1 reference

12 December 2020

Basal ganglia precursors found in aggregates following embryonic transplantation adopt a striatal phenotype in heterotopic locations

1 reference

12 December 2020

Generation of constitutively active recombinant caspases-3 and -6 by rearrangement of their subunits

1 reference

12 December 2020

Generation and characterization of embryonic striatal conditionally immortalized ST14A cells

1 reference

12 December 2020

An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

1 reference

12 December 2020

Nuclear and neuropil aggregates in Huntington's disease: relationship to neuropathology.

1 reference

12 December 2020

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

1 reference

12 December 2020

A cellular model that recapitulates major pathogenic steps of Huntington's disease

1 reference

12 December 2020

Recent advances in understanding the pathogenesis of Huntington's disease

1 reference

12 December 2020

Neurobiology of Huntington's disease

1 reference

12 December 2020

Apaf1 is required for mitochondrial pathways of apoptosis and brain development

1 reference

12 December 2020

The influence of huntingtin protein size on nuclear localization and cellular toxicity.

1 reference

12 December 2020

Neuronal degeneration in the basal ganglia and loss of pallido-subthalamic synapses in mice with targeted disruption of the Huntington's disease gene

1 reference

12 December 2020

Behavioural abnormalities and selective neuronal loss in HD transgenic mice expressing mutated full-length HD cDNA.

1 reference

12 December 2020

Inactivation of the mouse Huntington's disease gene homolog Hdh

1 reference

12 December 2020

Huntington disease and the related disorder, dentatorubral-pallidoluysian atrophy (DRPLA).

1 reference

12 December 2020

A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.

1 reference

12 December 2020

Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development

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12 December 2020

Truncated N-terminal fragments of huntingtin with expanded glutamine repeats form nuclear and cytoplasmic aggregates in cell culture.

1 reference

12 December 2020

Gene therapy of experimental brain tumors using neural progenitor cells

1 reference

12 December 2020

Neuropathological classification of Huntington's disease

1 reference

12 December 2020

A short term analysis of the behaviour of conditionally immortalized neuronal progenitors and primary neuroepithelial cells implanted into the fetal rat brain.

1 reference

12 December 2020

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 reference

12 December 2020

Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract

1 reference

12 December 2020

Life without huntingtin: normal differentiation into functional neurons

1 reference

12 December 2020

The cell cycle related differences in susceptibility of HL-60 cells to apoptosis induced by various antitumor agents

1 reference

12 December 2020

Caspase-8 is required for cell death induced by expanded polyglutamine repeats.

1 reference

12 December 2020

Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue

1 reference

12 December 2020

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

1 reference

12 December 2020

Neuronal intranuclear inclusions in polyglutamine diseases: nuclear weapons or nuclear fallout?

1 reference

12 December 2020

10.1523/JNEUROSCI.20-10-03705.2000

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10804212%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

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6 November 2019

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