Mutant huntingtin expression in clonal striatal cells: dissociation of inclusion formation and neuronal survival by caspase inhibition. (Q48298684)

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9 December 2019

title

Mutant huntingtin expression in clonal striatal cells: dissociation of inclusion formation and neuronal survival by caspase inhibition (English)

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9 December 2019

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12

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9 December 2019

author name string

M Kim

1

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9 December 2019

H S Lee

2

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9 December 2019

G LaForet

3

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9 December 2019

C McIntyre

4

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9 December 2019

E J Martin

5

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P Chang

6

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9 December 2019

T W Kim

7

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9 December 2019

M Williams

8

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9 December 2019

P H Reddy

9

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9 December 2019

D Tagle

10

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9 December 2019

F M Boyce

11

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9 December 2019

A Heller

13

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N Aronin

14

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M DiFiglia

15

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9 December 2019

language of work or name

English

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publication date

1 February 1999

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9 December 2019

published in

Journal of Neuroscience

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9 December 2019

volume

19

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9 December 2019

issue

3

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9 December 2019

page(s)

964-973

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Huntingtin localization in brains of normal and Huntington's disease patients

9 December 2019

cites work

1 reference

12 December 2020

Polyglutamine domains are substrates of tissue transglutaminase: does transglutaminase play a role in expanded CAG/poly-Q neurodegenerative diseases?

1 reference

12 December 2020

A DEVD-inhibited caspase other than CPP32 is involved in the commitment of cerebellar granule neurons to apoptosis induced by K+ deprivation.

1 reference

12 December 2020

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

1 reference

12 December 2020

Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract

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12 December 2020

Expression of normal and mutant huntingtin in the developing brain

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12 December 2020

Wild-type and mutant huntingtins function in vesicle trafficking in the secretory and endocytic pathways

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12 December 2020

Transglutaminase action imitates Huntington's disease: selective polymerization of Huntingtin containing expanded polyglutamine.

1 reference

12 December 2020

Intranuclear neuronal inclusions in Huntington's disease and dentatorubral and pallidoluysian atrophy: correlation between the density of inclusions and IT15 CAG triplet repeat length

1 reference

12 December 2020

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

1 reference

12 December 2020

Length of huntingtin and its polyglutamine tract influences localization and frequency of intracellular aggregates

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12 December 2020

Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models.

1 reference

12 December 2020

Intranuclear inclusions of expanded polyglutamine protein in spinocerebellar ataxia type 3.

1 reference

12 December 2020

The role of CED-3-related cysteine proteases in apoptosis of cerebellar granule cells.

1 reference

12 December 2020

A cellular model that recapitulates major pathogenic steps of Huntington's disease

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12 December 2020

Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene

1 reference

12 December 2020

Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak

1 reference

12 December 2020

The influence of huntingtin protein size on nuclear localization and cellular toxicity.

1 reference

12 December 2020

Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons

1 reference

12 December 2020

Truncated N-terminal fragments of huntingtin with expanded glutamine repeats form nuclear and cytoplasmic aggregates in cell culture.

1 reference

12 December 2020

Processing/activation of at least four interleukin-1beta converting enzyme-like proteases occurs during the execution phase of apoptosis in human monocytic tumor cells

1 reference

12 December 2020

Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo

1 reference

12 December 2020

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

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12 December 2020

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

1 reference

12 December 2020

Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract

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12 December 2020

Forskolin and dopamine D1 receptor activation increase huntingtin's association with endosomes in immortalized neuronal cells of striatal origin.

1 reference

12 December 2020

Suppression of aggregate formation and apoptosis by transglutaminase inhibitors in cells expressing truncated DRPLA protein with an expanded polyglutamine stretch.

1 reference

12 December 2020

Immortalized murine striatal neuronal cell lines expressing dopamine receptors and cholinergic properties

1 reference

12 December 2020

Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures

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12 December 2020

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

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12 December 2020

Immortalization of embryonic mesencephalic dopaminergic neurons by somatic cell fusion

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12 December 2020

10.1523/JNEUROSCI.19-03-00964.1999

Identifiers

DOI

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9 December 2019

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9 December 2019

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