Crystal Structure of the Vaccinia Virus Uracil-DNA Glycosylase in Complex with DNA. (Q40867415)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26045555%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

title

Crystal Structure of the Vaccinia Virus Uracil-DNA Glycosylase in Complex with DNA (English)

1 reference

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16 February 2020

Vaccinia Virus

1 reference

1

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16 February 2020

Nicolas Tarbouriech

2

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16 February 2020

Pascal Fender

3

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16 February 2020

author name string

Céline Contesto-Richefeu

4

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16 February 2020

Christophe N Peyrefitte

5

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16 February 2020

Frédéric Iseni

6

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16 February 2020

language of work or name

English

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publication date

4 June 2015

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Journal of Biological Chemistry

16 February 2020

published in

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16 February 2020

volume

290

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16 February 2020

page(s)

17923-17934

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16 February 2020

issue

29

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Uracil-DNA glycosylases-structural and functional perspectives on an essential family of DNA repair enzymes

16 February 2020

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Crystal structure of the vaccinia virus DNA polymerase holoenzyme subunit D4 in complex with the A20 N-terminal domain

24 September 2017

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Structure of the uracil complex ofVaccinia virusuracil DNA glycosylase

24 September 2017

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24 September 2017

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Evaluation of the role of the vaccinia virus uracil DNA glycosylase and A20 proteins as intrinsic components of the DNA polymerase holoenzyme

24 September 2017

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Vaccinia Virus D4 Mutants Defective in Processive DNA Synthesis Retain Binding to A20 and DNA

24 September 2017

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Uracil-DNA glycosylase: Structural, thermodynamic and kinetic aspects of lesion search and recognition

24 September 2017

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The simian varicella virus uracil DNA glycosylase and dUTPase genes are expressed in vivo, but are non-essential for replication in cell culture

24 September 2017

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Uracil DNA glycosylase uses DNA hopping and short-range sliding to trap extrahelical uracils

24 September 2017

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Enzymatic capture of an extrahelical thymine in the search for uracil in DNA

24 September 2017

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Inference of macromolecular assemblies from crystalline state

24 September 2017

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Crystal structure of vaccinia virus uracil-DNA glycosylase reveals dimeric assembly

24 September 2017

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24 September 2017

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New insights on the role of the gamma-herpesvirus uracil-DNA glycosylase leucine loop revealed by the structure of the Epstein-Barr virus enzyme in complex with an inhibitor protein

24 September 2017

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Vaccinia virus uracil DNA glycosylase interacts with the A20 protein to form a heterodimeric processivity factor for the viral DNA polymerase

24 September 2017

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24 September 2017

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Characterisation of the substrate specificity of homogeneous vaccinia virus uracil-DNA glycosylase

24 September 2017

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Vaccinia virus uracil DNA glycosylase has an essential role in DNA synthesis that is independent of its glycosylase activity: catalytic site mutations reduce virulence but not virus replication in cultured cells

24 September 2017

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24 September 2017

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hUNG2 is the major repair enzyme for removal of uracil from U:A matches, U:G mismatches, and U in single-stranded DNA, with hSMUG1 as a broad specificity backup

24 September 2017

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24 September 2017

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Lessons learned from structural results on uracil-DNA glycosylase

24 September 2017

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Uracil-DNA glycosylase-DNA substrate and product structures: conformational strain promotes catalytic efficiency by coupled stereoelectronic effects

24 September 2017

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24 September 2017

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24 September 2017

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Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA.

24 September 2017

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Crystal structure of a G:T/U mismatch-specific DNA glycosylase: mismatch recognition by complementary-strand interactions

24 September 2017

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Direct measurement of the substrate preference of uracil-DNA glycosylase

24 September 2017

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Construction of a vaccinia virus deficient in the essential DNA repair enzyme uracil DNA glycosylase by a complementing cell line

24 September 2017

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A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA

24 September 2017

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Mutations in active-site residues of the uracil-DNA glycosylase encoded by vaccinia virus are incompatible with virus viability

24 September 2017

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Human cytomegalovirus uracil DNA glycosylase is required for the normal temporal regulation of both DNA synthesis and viral replication

24 September 2017

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Crystal structure of human uracil-DNA glycosylase in complex with a protein inhibitor: protein mimicry of DNA

24 September 2017

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Nucleotide mimicry in the crystal structure of the uracil-DNA glycosylase-uracil glycosylase inhibitor protein complex

24 September 2017

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An N -Glycosidase from Escherichia coli That Releases Free Uracil from DNA Containing Deaminated Cytosine Residues

24 September 2017

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Expression of a uracil DNA glycosylase (UNG) inhibitor in mammalian cells: varicella-zoster virus can replicate in vitro in the absence of detectable UNG activity

24 September 2017

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The vaccinia virus-encoded uracil DNA glycosylase has an essential role in viral DNA replication

17 June 2018

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Gene UL2 of herpes simplex virus type 1 encodes a uracil-DNA glycosylase

17 June 2018

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A comparative study of uracil-DNA glycosylases from human and herpes simplex virus type 1.

17 June 2018

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The role of leucine 191 of Escherichia coli uracil DNA glycosylase in the formation of a highly stable complex with the substrate mimic, ugi, and in uracil excision from the synthetic substrates

19 August 2018

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19 August 2018

Identifiers

DOI

10.1074/JBC.M115.648352

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26045555%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

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16 February 2020

1 reference