Phosphoinositide-3 kinase-PKB/Akt pathway activation is involved in fibroblast Rat-1 transformation by human T-cell leukemia virus type I tax. (Q40797053)

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English	Phosphoinositide-3 kinase-PKB/Akt pathway activation is involved in fibroblast Rat-1 transformation by human T-cell leukemia virus type I tax.	scientific article

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scholarly article

1 reference

Europe PubMed Central

23 September 2017

Phosphoinositide-3 kinase-PKB/Akt pathway activation is involved in fibroblast Rat-1 transformation by human T-cell leukemia virus type I tax. (English)

1 reference

Europe PubMed Central

23 September 2017

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based on heuristic

inferred from title

Human T-lymphotropic virus 1

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based on heuristic

inferred from title

T-cell leukemia

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based on heuristic

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author name string

Liu Y

1

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Europe PubMed Central

23 September 2017

Wang Y

2

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Europe PubMed Central

23 September 2017

Yamakuchi M

3

1 reference

Europe PubMed Central

23 September 2017

Masuda S

4

1 reference

Europe PubMed Central

23 September 2017

Tokioka T

5

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Europe PubMed Central

23 September 2017

Yamaoka S

6

1 reference

Europe PubMed Central

23 September 2017

Maruyama I

7

1 reference

Europe PubMed Central

23 September 2017

Kitajima I

8

1 reference

Europe PubMed Central

23 September 2017

language of work or name

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publication date

1 May 2001

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Europe PubMed Central

23 September 2017

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Europe PubMed Central

23 September 2017

20

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Europe PubMed Central

23 September 2017

2514-2526

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Europe PubMed Central

23 September 2017

20

1 reference

Europe PubMed Central

23 September 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1204364

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Characterization of peripheral blood T-lymphocytes transduced with HTLV-I Tax mutants with different trans-activating phenotypes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

v-Crk activates the phosphoinositide 3-kinase/AKT pathway in transformation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

The akt kinase: molecular determinants of oncogenicity

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

The catalytic subunit of phosphoinositide 3-kinase: requirements for oncogenicity

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

Involvement of regulatory and catalytic subunits of phosphoinositide 3-kinase in NF-kappaB activation.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

Phosphoinositide kinases

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

IKKgamma mediates the interaction of cellular IkappaB kinases with the tax transforming protein of human T cell leukemia virus type 1.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

Molecular mechanism of tumorigenesis in mice transgenic for the human T cell leukemia virus Tax gene

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

Cellular survival: a play in three Akts

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

Downstream signalling events regulated by phosphatidylinositol 3-kinase activity.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

Phosphoinositide metabolism and the morphology of human erythrocytes

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

PI3K: downstream AKTion blocks apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

Functional activation of the long terminal repeat of human T-cell leukemia virus type I by a trans-acting factor

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

Phosphatidylinositol 4-kinases

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

Human T-cell leukemia virus type 1 Tax induction of NF-kappaB involves activation of the IkappaB kinase alpha (IKKalpha) and IKKbeta cellular kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

Expression of the complete human T-cell leukemia virus type I pX coding sequence as a functional protein in Escherichia coli

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

Development of leukemia in mice transgenic for the tax gene of human T-cell leukemia virus type I.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

IKKgamma serves as a docking subunit of the IkappaB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax protein

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

Akt signaling: linking membrane events to life and death decisions

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

Phosphatidylinositol 3-kinase: structure and expression of the 110 kd catalytic subunit

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

Adult T-cell leukemia: antigen in an ATL cell line and detection of antibodies to the antigen in human sera

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

Role of Adapter Function in Oncoprotein-mediated Activation of NF-κB

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

Induction of NF-kappaB by the Akt/PKB kinase

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

HTLV-1 Tax protein sensitizes cells to apoptotic cell death induced by DNA damaging agents.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

Ribozyme-based gene cleavage approach to chronic arthritis associated with human T cell leukemia virus type I: induction of apoptosis in synoviocytes by ablation of HTLV-I tax protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

Ablation of transplanted HTLV-I Tax-transformed tumors in mice by antisense inhibition of NF-kappa B

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

Detection of human T cell lymphotropic virus type I proviral DNA and its gene expression in synovial cells in chronic inflammatory arthropathy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

Activation of phosphatidylinositol 3-kinase is sufficient for cell cycle entry and promotes cellular changes characteristic of oncogenic transformation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

The human T-cell leukemia virus type-1 Tax protein regulates the activity of the IkappaB kinase complex

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

SHIP is a negative regulator of growth factor receptor-mediated PKB/Akt activation and myeloid cell survival

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

The phosphatidylinositol 4-phosphate 5-kinase family.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

Differential roles of Akt, Rac, and Ral in R-Ras-mediated cellular transformation, adhesion, and survival

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

Transformation by v-Src: Ras-MAPK and PI3K-mTOR mediate parallel pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

The human T-lymphotropic virus type I tax gene can cooperate with the ras oncogene to induce neoplastic transformation of cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

Cellular transcription factors and regulation of IL-2 receptor gene expression by HTLV-I tax gene product.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

Identification and quantification of polyphosphoinositides produced in response to platelet-derived growth factor stimulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

PIK3CA is implicated as an oncogene in ovarian cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

Persistent activation of NF-kappaB by the tax transforming protein of HTLV-1: hijacking cellular IkappaB kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

Requirement for both Shc and phosphatidylinositol 3' kinase signaling pathways in polyomavirus middle T-mediated mammary tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

21 January 2018

Human T-cell leukemia virus type I Tax induces expression of the Rel-related family of kappa B enhancer-binding proteins: evidence for a pretranslational component of regulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

7 January 2021

based on heuristic

inferred from DOI database lookup

Cytoplasmic forms of human T-cell leukemia virus type 1 Tax induce NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

7 January 2021

based on heuristic

inferred from DOI database lookup

Immortalization of CD4(+) and CD8(+) T lymphocytes by human T-cell leukemia virus type 1 Tax mutants expressed in a functional molecular clone

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

7 January 2021

based on heuristic

inferred from DOI database lookup

The human T-cell leukemia virus type I Tax protein induces apoptosis which is blocked by the Bcl-2 protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204364

7 January 2021

based on heuristic

inferred from DOI database lookup

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10.1038/SJ.ONC.1204364

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Europe PubMed Central

23 September 2017

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1 reference

Europe PubMed Central

23 September 2017

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