Role of perforin in controlling B-cell hyperactivity and humoral autoimmunity (Q40735676)

23 September 2017

Role of perforin in controlling B-cell hyperactivity and humoral autoimmunity (English)

1 reference

23 September 2017

A Shustov

1

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23 September 2017

I Luzina

2

1 reference

23 September 2017

P Nguyen

3

1 reference

23 September 2017

J C Papadimitriou

4

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23 September 2017

B Handwerger

5

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23 September 2017

K B Elkon

6

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23 September 2017

C S Via

7

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23 September 2017

language of work or name

English

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publication date

1 September 2000

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Journal of Clinical Investigation

23 September 2017

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23 September 2017

106

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23 September 2017

6

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23 September 2017

R39-47

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An increased prevalence of Epstein-Barr virus infection in young patients suggests a possible etiology for systemic lupus erythematosus

23 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381389

Interleukin-10 promotes activation-induced cell death of SLE lymphocytes mediated by Fas ligand

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381389

Graft-versus-host-disease-associated lymphoid hypoplasia and B cell dysfunction is dependent upon donor T cell-mediated Fas-ligand function, but not perforin function

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381389

Decreased tumor surveillance in perforin-deficient mice

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381389

The role of cell-mediated cytotoxicity in acute GVHD after MHC-matched allogeneic bone marrow transplantation in mice

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381389

Cytotoxic T cells deficient in both functional fas ligand and perforin show residual cytolytic activity yet lose their capacity to induce lethal acute graft-versus-host disease

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381389

Nucleosome: a major immunogen for pathogenic autoantibody-inducing T cells of lupus

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381389

Genesis and evolution of antichromatin autoantibodies in murine lupus implicates T-dependent immunization with self antigen

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381389

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381389

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381389

The cytokine network in the pathogenesis of systemic lupus erythematosus and possible therapeutic implications

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381389

Fas involvement in Ca(2+)-independent T cell-mediated cytotoxicity

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381389

Molecular pathways of CTL-mediated cytotoxicity

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381389

Purification and properties of cytoplasmic granules from cytotoxic rat LGL tumors

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381389

Autoantibodies in chronic graft versus host result from cognate T-B interactions

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381389

The lpr and gld genes in systemic autoimmunity: life and death in the Fas lane

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381389

Vasculitis in the Palmerston North mouse model of lupus: phenotype and cytokine production profile of infiltrating cells.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381389

Impaired nonrestricted cytolytic activity in systemic lupus erythematosus: involvement of a pathway independent of Fas, tumor necrosis factor, and extracellular ATP that is associated with little detectable perforin

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381389

Cytotoxicity in graft-versus-host reaction. I. Role of donor and host spleen cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381389

Murine chronic graft-versus-host disease as a model for lupus nephritis

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381389

Tumour necrosis factor-alpha in murine autoimmune 'lupus' nephritis

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381389

Lymphocyte abnormalities in human lupus

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381389

CD8+ T cells clear influenza virus by perforin or Fas-dependent processes.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381389

Cytotoxic responses to alloantigens in systemic lupus erythematosus.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381389

Critical role of interleukin-2 in the development of acute graft-versus-host disease.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381389

Impaired polyclonal T cell cytolytic activity. A possible risk factor for systemic lupus erythematosus.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=381389

Further characterization of the autoantibody response of Palmerston North mice

19 August 2018

1 reference

12 December 2020

Repopulation of host lymphohematopoietic systems by donor cells during graft-versus-host reaction in unirradiated adult F1 mice injected with parental lymphocytes

1 reference

12 December 2020

Cytokine gene expression after in vivo primary immunization with goat antibody to mouse IgD antibody

1 reference

12 December 2020

Graft-versus-host reactions: clues to the etiopathology of a spectrum of immunological diseases

1 reference

12 December 2020

Role of cytotoxic T lymphocytes in the prevention of lupus-like disease occurring in a murine model of graft-vs-host disease

1 reference

12 December 2020

The kidneys of NZB-B1, NZO-B1, NZC-B1 and NZY-B1 mice

1 reference

12 December 2020

A systemic lupus erythematosus (SLE)-like disease in mice induced by abnormal T-B cell cooperation. Preferential formation of autoantibodies characteristic of SLE

1 reference

12 December 2020

Two distinct pathways of specific killing revealed by perforin mutant cytotoxic T lymphocytes

1 reference

12 December 2020

Kinetics of Th1 and Th2 cytokine production during the early course of acute and chronic murine graft-versus-host disease. Regulatory role of donor CD8+ T cells

1 reference

12 December 2020

Cytokine gene expression in mice undergoing chronic graft-versus-host disease

1 reference

12 December 2020

Perforin protects against autoimmunity in lupus-prone mice

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12 December 2020

Microchimerism and autoimmune disease

1 reference

12 December 2020

Differential expression of Fas and Fas ligand in acute and chronic graft-versus-host disease: up-regulation of Fas and Fas ligand requires CD8+ T cell activation and IFN-gamma production

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI8876

1 reference

23 September 2017

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23 September 2017

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