Phosphorylation of 338SSYY341 regulates specific interaction between Raf-1 and MEK1. (Q40702461)

22 September 2017

Phosphorylation of 338SSYY341 regulates specific interaction between Raf-1 and MEK1. (English)

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22 September 2017

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2

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22 September 2017

5

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22 September 2017

Xiaoqin Xiang

1

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22 September 2017

Christine A Waelde

series ordinal

3

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22 September 2017

Rong Wen

series ordinal

4

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22 September 2017

language of work or name

English

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publication date

19 September 2002

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Journal of Biological Chemistry

22 September 2017

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22 September 2017

277

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22 September 2017

44996-45003

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22 September 2017

47

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Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions

22 September 2017

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https://api.crossref.org/works/10.1074%2FJBC.M203953200

The complexity of Raf-1 regulation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M203953200

Dephosphorylation of Ser-259 regulates Raf-1 membrane association

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M203953200

Cyclic AMP-dependent kinase regulates Raf-1 kinase mainly by phosphorylation of serine 259.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203953200

14-3-3 antagonizes Ras-mediated Raf-1 recruitment to the plasma membrane to maintain signaling fidelity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203953200

Regulation of Raf-1 activation and signalling by dephosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203953200

Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203953200

Phosphorylation and regulation of Raf by Akt (protein kinase B)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203953200

Regulation of Raf by Akt controls growth and differentiation in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203953200

Regulation of Raf-Akt Cross-talk

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M203953200

Negative regulation of the serine/threonine kinase B-Raf by Akt

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M203953200

Positive and negative regulation of Raf kinase activity and function by phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M203953200

Protein kinase C alpha activates RAF-1 by direct phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M203953200

The MEK kinase activity of the catalytic domain of RAF-1 is regulated independently of Ras binding in T cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M203953200

Regulation of the Raf-1 kinase domain by phosphorylation and 14-3-3 association.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M203953200

Critical tyrosine residues regulate the enzymatic and biological activity of Raf-1 kinase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M203953200

Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203953200

Phosphorylation of Raf-1 serine 338-serine 339 is an essential regulatory event for Ras-dependent activation and biological signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203953200

The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M203953200

S338 phosphorylation of Raf-1 is independent of phosphatidylinositol 3-kinase and Pak3

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M203953200

Phosphorylation site specificity of the Pak-mediated regulation of Raf-1 and cooperativity with Src.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M203953200

Microtubule integrity regulates Pak leading to Ras-independent activation of Raf-1. insights into mechanisms of Raf-1 activation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M203953200

Interaction between active Pak1 and Raf-1 is necessary for phosphorylation and activation of Raf-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203953200

Oligomerization activates c-Raf-1 through a Ras-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203953200

The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203953200

Definition of the human raf amino-terminal regulatory region by deletion mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203953200

A different function for a critical tryptophan in c-Raf and Hck.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203953200

A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203953200

Human DNA sequence homologous to the transforming gene (mos) of Moloney murine sarcoma virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203953200

KSR, a novel protein kinase required for RAS signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203953200

The role of the linker between the SH2 domain and catalytic domain in the regulation and function of Src.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203953200

Raf-1-associated Protein Phosphatase 2A as a Positive Regulator of Kinase Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203953200

Requirement of Ras-GTP-Raf Complexes for Activation of Raf-1 by Protein Kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203953200

Oncogenes, growth factors and phorbol esters regulate Raf-1 through common mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203953200

Identification of the 14.3.3 zeta domains important for self-association and Raf binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203953200

Raf-1/MEK/MAPK pathway is necessary for the G2/M transition induced by nocodazole

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203953200

21 January 2018

Identifiers

DOI

10.1074/JBC.M203953200

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22 September 2017

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