Distinct Roles of RAG1 and RAG2 in Binding the V(D)J Recombination Signal Sequences (Q33775546)

29 July 2017

title

Distinct roles of RAG1 and RAG2 in binding the V(D)J recombination signal sequences (English)

1 reference

29 July 2017

Distinct Roles of RAG1 and RAG2 in Binding the V(D)J Recombination Signal Sequences (English)

1 reference

https://api.crossref.org/works/10.1128/MCB.18.8.4670

1 January 2025

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9671477

1 January 2025

genetic recombination

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9671477

1 January 2025

author name string

Y. Akamatsu

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9671477

1 January 2025

M. A. Oettinger

series ordinal

2

1 reference

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publication date

1 August 1998

1 reference

29 July 2017

August 1998

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9671477

https://europepmc.org/articles/pmc109053?pdf=render

1 January 2025

language of work or name

English

0 references

work available at URL

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9671477

http://mcb.asm.org/cgi/content/abstract/18/8/4670

1 January 2025

online access status

open access

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https://europepmc.org/articles/PMC109053

1 January 2025

file format

HyperText Markup Language

online access status

open access

content deliverer

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9671477

https://europepmc.org/articles/PMC109053?pdf=render

1 January 2025

1 reference

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https://journals.asm.org/doi/pdf/10.1128/MCB.18.8.4670

1 January 2025

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https://www.tandfonline.com/doi/pdf/10.1128/MCB.18.8.4670

1 January 2025

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Molecular and Cellular Biology

1 January 2025

published in

1 reference

29 July 2017

volume

18

1 reference

29 July 2017

issue

8

1 reference

29 July 2017

page(s)

4670-4678

1 reference

describes a project that uses

29 July 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC109053/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Functional Analysis of Coordinated Cleavage in V(D)J Recombination

1 reference

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Footprint analysis of the RAG protein recombination signal sequence complex for V(D)J type recombination.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109053

A complex of RAG-1 and RAG-2 proteins persists on DNA after single-strand cleavage at V(D)J recombination signal sequences

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109053

A stable RAG1-RAG2-DNA complex that is active in V(D)J cleavage

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109053

RAG1 mediates signal sequence recognition and recruitment of RAG2 in V(D)J recombination

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109053

DNA sequence and structure requirements for cleavage of V(D)J recombination signal sequences

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109053

Distinct DNA sequence and structure requirements for the two steps of V(D)J recombination signal cleavage

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109053

The RAG1 and RAG2 proteins establish the 12/23 rule in V(D)J recombination

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109053

Initiation of V(D)J recombination in vitro obeying the 12/23 rule

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109053

DNA double-strand break repair and V(D)J recombination: involvement of DNA-PK.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109053

Dispensable sequence motifs in the RAG-1 and RAG-2 genes for plasmid V(D)J recombination

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109053

Expression and V(D)J recombination activity of mutated RAG-1 proteins

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109053

Analysis of regions of RAG-2 important for V(D)J recombination

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109053

Definition of a core region of RAG-2 that is functional in V(D)J recombination

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109053

The mechanism of V(D)J joining: lessons from molecular, immunological, and comparative analyses

4 July 2018

1 reference

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Essential residues in V(D)J recombination signals

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109053

Initiation of V(D)J recombination in a cell-free system.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109053

Correlation of lac operator DNA imino proton exchange kinetics with its function

4 July 2018

1 reference

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Somatic generation of antibody diversity

4 July 2018

1 reference

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57 Sequencing end-labeled DNA with base-specific chemical cleavages

4 July 2018

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c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109053

Two pairs of recombination signals are sufficient to cause immunoglobulin V-(D)-J joining

4 July 2018

1 reference

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The V(D)J recombination activating gene, RAG-1.

4 July 2018

1 reference

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RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109053

Base-pairing shift in the major groove of (CA)n tracts by B-DNA crystal structures

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109053

Nuclease activity of 1,10-phenanthroline-copper in study of protein-DNA interactions

4 July 2018

1 reference

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The homeodomain region of Rag-1 reveals the parallel mechanisms of bacterial and V(D)J recombination

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109053

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109053

Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109053

RAG-1 mutations that affect the target specificity of V(D)j recombination: a possible direct role of RAG-1 in site recognition.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=109053

V(D)J recombination: a functional definition of the joining signals

30 October 2018

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12 December 2020

V(D)J recombination in mouse thymocytes: Double-strand breaks near T cell receptor δ rearrangement signals

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12 December 2020

V(D)J recombination: broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes

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12 December 2020

Double-strand signal sequence breaks in V(D)J recombination are blunt, 5'-phosphorylated, RAG-dependent, and cell cycle regulated

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12 December 2020

Regions of RAG1 protein critical for V(D)J recombination

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12 December 2020

14

6

1205

Hopp T. P.

1988

1 reference

https://api.crossref.org/works/10.1128/MCB.18.8.4670

[20] Nuclease activity of 1,10-phenanthroline-copper in study of protein—DNA interactions

1 January 2025

series ordinal

33

1 reference

https://api.crossref.org/works/10.1128/MCB.18.8.4670

1 January 2025

Identifiers

1 reference

29 July 2017

1 reference

29 July 2017

1 reference