Suppression of high-fidelity double-strand break repair in mammalian chromosomes by pifithrin-alpha, a chemical inhibitor of p53. (Q40679903)

22 September 2017

Suppression of high-fidelity double-strand break repair in mammalian chromosomes by pifithrin-alpha, a chemical inhibitor of p53. (English)

1 reference

22 September 2017

Yunfu Lin

1

1 reference

PubMed ID

12509264

22 September 2017

Barbara Criscuolo Waldman

series ordinal

2

1 reference

PubMed ID

12509264

22 September 2017

Alan S Waldman

series ordinal

3

1 reference

22 September 2017

1 January 2003

1 reference

22 September 2017

1 reference

22 September 2017

2

1 reference

22 September 2017

1

1 reference

22 September 2017

1-11

1 reference

DNA double-strand breaks: signaling, repair and the cancer connection

22 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900183-0

7 January 2021

Chromosomal stability and the DNA double-stranded break connection

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900183-0

7 January 2021

Partners and pathwaysrepairing a double-strand break.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900183-0

7 January 2021

DNA double strand break repair in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900183-0

7 January 2021

Multiple pathways for repair of DNA double-strand breaks in mammalian chromosomes

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900183-0

7 January 2021

Homology-directed repair is a major double-strand break repair pathway in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900183-0

7 January 2021

Promiscuous patching of broken chromosomes in mammalian cells with extrachromosomal DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900183-0

7 January 2021

Repair of a specific double-strand break generated within a mammalian chromosome by yeast endonuclease I-SceI.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900183-0

7 January 2021

p53 protein at the hub of cellular DNA damage response pathways through sequence-specific and non-sequence-specific DNA binding

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900183-0

7 January 2021

p53, the cellular gatekeeper for growth and division

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900183-0

7 January 2021

p53: puzzle and paradigm

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900183-0

7 January 2021

Mutant p53 proteins stimulate spontaneous and radiation-induced intrachromosomal homologous recombination independently of the alteration of the transactivation activity and of the G1 checkpoint.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900183-0

7 January 2021

Inactivation of p53 results in high rates of homologous recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900183-0

7 January 2021

Increase of spontaneous intrachromosomal homologous recombination in mammalian cells expressing a mutant p53 protein

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900183-0

7 January 2021

A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900183-0

7 January 2021

Normal breast epithelial cells induce p53-dependent apoptosis and p53-independent cell cycle arrest of breast cancer cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900183-0

7 January 2021

Vanadate-Induced Cell Growth Arrest is p53-dependent through Activation of p21 in C141 Cells

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900183-0

7 January 2021

Rescue of neural tube defects in Pax-3-deficient embryos by p53 loss of function: implications for Pax-3- dependent development and tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900183-0

7 January 2021

Wild-type and mutated presenilins 2 trigger p53-dependent apoptosis and down-regulate presenilin 1 expression in HEK293 human cells and in murine neurons

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900183-0

7 January 2021

Resveratrol induces apoptosis in thyroid cancer cell lines via a MAPK- and p53-dependent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900183-0

7 January 2021

Pifithrin-alpha, an inhibitor of p53, enhances the genetic instability induced by etoposide (VP16) in human lymphoblastoid cells treated in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900183-0

7 January 2021

Sodium butyrate induces P53-independent, Fas-mediated apoptosis in MCF-7 human breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900183-0

7 January 2021

Doxorubicin induces apoptosis and CD95 gene expression in human primary endothelial cells through a p53-dependent mechanism.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900183-0

7 January 2021

p21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900183-0

7 January 2021

Neurons are protected from excitotoxic death by p53 antisense oligonucleotides delivered in anionic liposomes

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900183-0

7 January 2021

A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid beta-peptide.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900183-0

7 January 2021

Nucleotide sequence of the thymidine kinase gene of herpes simplex virus type 1

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900183-0

7 January 2021

Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900183-0

7 January 2021

Identification of a novel p53 promoter element involved in genotoxic stress-inducible p53 gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900183-0

7 January 2021

A role for p53 in DNA end rejoining by human cell extracts

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900183-0

7 January 2021

Effect of wild-type, S15D and R175H p53 proteins on DNA end joining in vitro: potential mechanism of DNA double-strand break repair modulation.

1 reference

https://api.crossref.org/works/10.1016%2FS1568-7864%2802%2900183-0

7 January 2021

10.1016/S1568-7864(02)00183-0

Identifiers

DOI

1 reference

22 September 2017

1 reference

PubMed ID

12509264