Interaction of Epstein-Barr virus latent membrane protein 1 with SCFHOS/beta-TrCP E3 ubiquitin ligase regulates extent of NF-kappaB activation. (Q40629419)

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scientific article published on 30 September 2003

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English	Interaction of Epstein-Barr virus latent membrane protein 1 with SCFHOS/beta-TrCP E3 ubiquitin ligase regulates extent of NF-kappaB activation.	scientific article published on 30 September 2003

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scholarly article

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19 December 2019

Interaction of Epstein-Barr virus latent membrane protein 1 with SCFHOS/beta-TrCP E3 ubiquitin ligase regulates extent of NF-kappaB activation (English)

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19 December 2019

Epstein–Barr virus

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membrane protein

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based on heuristic

inferred from title

Andrey Parkhitko

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19 December 2019

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Weigang Tang

1

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19 December 2019

Oleg A Pavlish

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19 December 2019

Vladimir S Spiegelman

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19 December 2019

Serge Y Fuchs

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30 September 2003

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19 December 2019

Journal of Biological Chemistry

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19 December 2019

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19 December 2019

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19 December 2019

48942-48949

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19 December 2019

An EBV membrane protein expressed in immortalized lymphocytes transforms established rodent cells.

1 reference

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21 January 2018

Expression of the Epstein-Barr virus latent membrane protein 1 induces B cell lymphoma in transgenic mice

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Inhibition of transforming growth factor beta signaling and Smad-dependent activation of transcription by the Latent Membrane Protein 1 of Epstein-Barr virus

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Epstein-barr virus transformation: involvement of latent membrane protein 1-mediated activation of NF-kappaB.

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LMP1 structure and signal transduction

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CD40 and its viral mimic, LMP1: similar means to different ends

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Association of TRAF1, TRAF2, and TRAF3 with an Epstein-Barr virus LMP1 domain important for B-lymphocyte transformation: role in NF-kappaB activation

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21 January 2018

The Epstein-Barr virus oncogene product latent membrane protein 1 engages the tumor necrosis factor receptor-associated death domain protein to mediate B lymphocyte growth transformation and activate NF-kappaB

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21 January 2018

TRADD domain of Epstein-Barr virus transforming protein LMP1 is essential for inducing immortalization and suppressing senescence of primary rodent fibroblasts

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21 January 2018

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

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NF-kappaB and cell-cycle regulation: the cyclin connection

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21 January 2018

The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family

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21 January 2018

Latent membrane protein 1 of Epstein-Barr virus mimics a constitutively active receptor molecule.

1 reference

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21 January 2018

Epstein-Barr virus-transforming protein latent infection membrane protein 1 activates transcription factor NF-kappaB through a pathway that includes the NF-kappaB-inducing kinase and the IkappaB kinases IKKalpha and IKKbeta

1 reference

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21 January 2018

A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif

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21 January 2018

Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

1 reference

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21 January 2018

Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP

1 reference

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21 January 2018

The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

1 reference

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21 January 2018

SCF and Cullin/Ring H2-based ubiquitin ligases

1 reference

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21 January 2018

Isolation and sequencing of the Epstein-Barr virus BNLF-1 gene (LMP1) from a Chinese nasopharyngeal carcinoma

1 reference

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21 January 2018

Sequence variation in the Epstein-Barr virus latent membrane protein 1.

1 reference

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21 January 2018

Transmembrane domains 1 and 2 of the latent membrane protein 1 of Epstein-Barr virus contain a lipid raft targeting signal and play a critical role in cytostasis

1 reference

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21 January 2018

LMP-1's transmembrane domains encode multiple functions required for LMP-1's efficient signaling

1 reference

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21 January 2018

Identification of functional differences between prototype Epstein-Barr virus-encoded LMP1 and a nasopharyngeal carcinoma-derived LMP1 in human epithelial cells.

1 reference

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21 January 2018

Cytostatic effect of Epstein-Barr virus latent membrane protein-1 analyzed using tetracycline-regulated expression in B cell lines

1 reference

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21 January 2018

The amino-terminus and membrane-spanning domains of LMP-1 inhibit cell proliferation

1 reference

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21 January 2018

The transmembrane domains of the EBV-encoded latent membrane protein 1 (LMP1) variant CAO regulate enhanced signalling activity

1 reference

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21 January 2018

Degradation of the epstein-barr virus latent membrane protein 1 (LMP1) by the ubiquitin-proteasome pathway. Targeting via ubiquitination of the N-terminal residue

1 reference

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21 January 2018

The LMP1 gene isolated from Russian nasopharyngeal carcinoma has no 30-bp deletion.

1 reference

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21 January 2018

HOS, a human homolog of Slimb, forms an SCF complex with Skp1 and Cullin1 and targets the phosphorylation-dependent degradation of IkappaB and beta-catenin.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M307962200

21 January 2018

Induction of homologue of Slimb ubiquitin ligase receptor by mitogen signaling

1 reference

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21 January 2018

Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation

1 reference

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21 January 2018

Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain

1 reference

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21 January 2018

Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha

1 reference

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21 January 2018

Inhibition of HOS expression and activities by Wnt pathway

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The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways

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21 January 2018

Control of meiotic and mitotic progression by the F box protein beta-Trcp1 in vivo

1 reference

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21 January 2018

Pseudosubstrate regulation of the SCF(beta-TrCP) ubiquitin ligase by hnRNP-U

1 reference

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21 January 2018

ATF4 degradation relies on a phosphorylation-dependent interaction with the SCF(betaTrCP) ubiquitin ligase

1 reference

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21 January 2018

SCF(beta)(-TrCP) ubiquitin ligase-mediated processing of NF-kappaB p105 requires phosphorylation of its C-terminus by IkappaB kinase

1 reference

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21 January 2018

Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase

1 reference

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1 reference

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The human immunodeficiency virus type 1 Vpu protein inhibits NF-kappa B activation by interfering with beta TrCP-mediated degradation of Ikappa B.

1 reference

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21 January 2018

IkappaBalpha ubiquitination is catalyzed by an SCF-like complex containing Skp1, cullin-1, and two F-box/WD40-repeat proteins, betaTrCP1 and betaTrCP2.

1 reference

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21 January 2018

Impaired degradation of inhibitory subunit of NF-kappa B (I kappa B) and beta-catenin as a result of targeted disruption of the beta-TrCP1 gene

1 reference

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21 January 2018

betaTrCP-mediated proteolysis of NF-kappaB1 p105 requires phosphorylation of p105 serines 927 and 932.

1 reference

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21 January 2018

Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase

1 reference

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Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex

1 reference

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Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

1 reference

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Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase

1 reference

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Role of LMP1 in immune control of EBV infection.

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The molecular epidemiology and evolution of Epstein-Barr virus: sequence variation and genetic recombination in the latent membrane protein-1 gene

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Molecular dissection of the interactions among IkappaBalpha, FWD1, and Skp1 required for ubiquitin-mediated proteolysis of IkappaBalpha

1 reference

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21 January 2018

Signature amino acid changes in latent membrane protein 1 distinguish Epstein-Barr virus strains

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21 January 2018

Epstein-Barr virus strain variation in nasopharyngeal carcinoma from the endemic and non-endemic regions of China

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Wnt/beta-catenin signaling induces the expression and activity of betaTrCP ubiquitin ligase receptor

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The 30-bp deletion variant: a polymorphism of latent membrane protein 1 prevalent in endemic and non-endemic areas of nasopharyngeal carcinomas in China

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M307962200

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14523018%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14523018%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

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