Extracellular acidosis is a novel danger signal alerting innate immunity via the NLRP3 inflammasome. (Q40600319)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23530046%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

title

Extracellular acidosis is a novel danger signal alerting innate immunity via the NLRP3 inflammasome (English)

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27 February 2020

1 reference

1

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27 February 2020

Tommy Nordström

2

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27 February 2020

Katariina Öörni

6

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27 February 2020

Katariina Nurmi

3

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27 February 2020

author name string

Karl E O Åkerman

4

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27 February 2020

Petri T Kovanen

5

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27 February 2020

Kari K Eklund

7

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27 February 2020

language of work or name

English

0 references

publication date

25 March 2013

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27 February 2020

number of pages

10

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Journal of Biological Chemistry

inferred from page(s)

published in

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27 February 2020

volume

288

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27 February 2020

issue

19

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27 February 2020

page(s)

13410-13419

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An update on the pathology and clinical management of gouty arthritis

27 February 2020

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Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression

22 September 2017

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22 September 2017

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Identification of the amino acid residues in the extracellular domain of rat P2X(7) receptor involved in functional inhibition by acidic pH.

22 September 2017

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Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

22 September 2017

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P2X7 receptor differentially couples to distinct release pathways for IL-1beta in mouse macrophage

22 September 2017

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22 September 2017

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pH dependence and inhibition by extracellular calcium of proton currents via plasmalemmal vacuolar-type H+-ATPase in murine osteoclasts

22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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Apoptosis induced in Jurkat cells by several agents is preceded by intracellular acidification

22 September 2017

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22 September 2017

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Changes in intramitochondrial and cytosolic pH: early events that modulate caspase activation during apoptosis

22 September 2017

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25 September 2017

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25 September 2017

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Monitoring intracellular pH changes in response to osmotic stress and membrane transport activity using 5-chloromethylfluorescein

25 September 2017

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15 June 2018

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15 June 2018

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15 June 2018

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15 June 2018

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15 June 2018

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20 August 2018

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20 August 2018

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20 August 2018

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20 August 2018

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20 August 2018

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20 August 2018

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20 August 2018

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20 August 2018

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20 August 2018

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Effects of bafilomycin A1 on functional capabilities of LPS-activated alveolar macrophages

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12 December 2020

Bactericidal activity of alveolar macrophages is suppressed by V-ATPase inhibition

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12 December 2020

On the viscosity and pH of synovial fluid and the pH of blood

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Human monocyte interleukin-1beta posttranslational processing. Evidence of a volume-regulated response

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12 December 2020

Stability and oligomeric equilibria of refolded interleukin-1beta converting enzyme

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12 December 2020

Mechanisms involved in the acidosis enhancement of the isoproterenol-induced phosphorylation of phospholamban in the intact heart

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12 December 2020

Relative roles of Na+/H+ exchange and vacuolar-type H+ ATPases in regulating cytoplasmic pH and function in murine peritoneal macrophages

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pH Heterogeneity of human and rabbit atherosclerotic plaques; a new insight into detection of vulnerable plaque

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Processing of precursor interleukin 1 beta and inflammatory disease

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Human pro-IL-1 beta gene expression in monocytic cells is regulated by two distinct pathways

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Synovial fluid acidosis correlates with radiological joint destruction in rheumatoid arthritis knee joints

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Bafilomycin A1 inhibits lysosomal, phagosomal, and plasma membrane H(+)-ATPase and induces lysosomal enzyme secretion in macrophages

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Ion channel expression in PMA-differentiated human THP-1 macrophages

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12 December 2020

Synovial fluid pH, lactate, oxygen and carbon dioxide partial pressure in various joint diseases

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Changes in the interstitial pH of dog myocardium in response to local ischemia, hypoxia, hyper- and hypocapnia, measured continuously by means of glass microelectrodes

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Copper(II) complexation properties and surfactant activity of 3-[N, N-bis(2-hydroxyethyl)amino]-2-hydroxypropanesulfonic acid and N-(2-Hydroxyethyl)piperazine-N'-2-hydroxypropanesulfonic acid pH buffers which may affect trace metal speciation in in

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Human monocyte stimulus-coupled IL-1beta posttranslational processing: modulation via monovalent cations

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Identifiers

DOI

10.1074/JBC.M112.426254

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23530046%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23530046%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

1 reference