The tumor suppressor p16(INK4a) gene is a regulator of apoptosis induced by ultraviolet light and cisplatin (Q40539192)

21 September 2017

The tumor suppressor p16(INK4a) gene is a regulator of apoptosis induced by ultraviolet light and cisplatin (English)

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21 September 2017

Mai A Al-Mohanna

1

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21 September 2017

Pulicat S Manogaran

2

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21 September 2017

Zuha Al-Mukhalafi

3

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21 September 2017

Khaled A Al-Hussein

4

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21 September 2017

Abdelilah Aboussekhra

5

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21 September 2017

language of work or name

English

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publication date

1 January 2004

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21 September 2017

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21 September 2017

23

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21 September 2017

201-212

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21 September 2017

1

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1206927

21 September 2017

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cites work

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Cell death: the significance of apoptosis

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p53-Dependent and -independent responses to cisplatin in mouse testicular teratocarcinoma cells

21 January 2018

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Impaired DNA repair capacity in skin fibroblasts from various hereditary cancer-prone syndromes.

21 January 2018

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7 January 2021

Transgenic models of lymphoid neoplasia and development of a pan-hematopoietic vector

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7 January 2021

p53-dependent apoptosis or growth arrest induced by different forms of radiation in U2OS cells: p21WAF1/CIP1 repression in UV induced apoptosis

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7 January 2021

p53 is dispensable for UV-induced cell cycle arrest at late G(1) in mammalian cells

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7 January 2021

Roles for p53 in growth arrest and apoptosis: putting on the brakes after genotoxic stress

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7 January 2021

p21-induced cycle arrest in G1 protects cells from apoptosis induced by UV-irradiation or RNA polymerase II blockage.

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7 January 2021

Sunlight and the onset of skin cancer

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7 January 2021

Small contribution of G1 checkpoint control manipulation to modulation of p53-mediated apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206927

7 January 2021

Ultraviolet light-induced DNA damage triggers apoptosis in nucleotide excision repair-deficient cells via Bcl-2 decline and caspase-3/-8 activation

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7 January 2021

Is cisplatin-induced cell death always produced by apoptosis?

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7 January 2021

The Hallmarks of Cancer

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7 January 2021

Germline p16 mutations in familial melanoma

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7 January 2021

Apoptosis: a link between cancer genetics and chemotherapy

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7 January 2021

A cell cycle regulator potentially involved in genesis of many tumor types

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7 January 2021

Down-regulation of bcl-2 is associated with p16INK4-mediated apoptosis in non-small cell lung cancer cells

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7 January 2021

Activation of caspase-3 and cleavage of Rb are associated with p16-mediated apoptosis in human non-small cell lung cancer cells

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7 January 2021

p53 status and the efficacy of cancer therapy in vivo

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7 January 2021

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

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7 January 2021

Induced expression of p16(INK4a) inhibits both CDK4- and CDK2-associated kinase activity by reassortment of cyclin-CDK-inhibitor complexes

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206927

7 January 2021

Persistent DNA damage induced by ultraviolet light inhibits p21waf1 and bax expression: implications for DNA repair, UV sensitivity and the induction of apoptosis

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7 January 2021

Involvement of p16CDKN2A in cell cycle delays after low dose UV irradiation

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7 January 2021

Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers

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7 January 2021

The cyclin-dependent kinase inhibitor p21 (WAF1) is required for survival of differentiating neuroblastoma cells

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7 January 2021

Genetic determinants of p53-induced apoptosis and growth arrest

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206927

7 January 2021

Regulation of apoptosis by bcl-2 family proteins and its role in cancer and chemoresistance.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206927

7 January 2021

Adenovirally transferred p16INK4/CDKN2 and p53 genes cooperate to induce apoptotic tumor cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206927

7 January 2021

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206927

7 January 2021

Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206927

7 January 2021

Adenovirus-mediated gene transfer of P16INK4/CDKN2 into bax-negative colon cancer cells induces apoptosis and tumor regression in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206927

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1206927

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Dimensions Publication ID

21 September 2017

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