Endogenously released Smac is insufficient to mediate cell death of human lung carcinoma in response to etoposide (Q40537809)

21 September 2017

Endogenously released Smac is insufficient to mediate cell death of human lung carcinoma in response to etoposide (English)

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21 September 2017

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3

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21 September 2017

Babett Bartling

1

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PubMed ID

15242764

21 September 2017

Rolf Lewensohn

series ordinal

2

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PubMed ID

15242764

21 September 2017

language of work or name

English

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publication date

1 August 2004

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Experimental Cell Research

21 September 2017

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21 September 2017

298

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21 September 2017

1

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21 September 2017

83-95

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21 September 2017

Cancer statistics, 2001

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.007

Tumor cell death induced by topoisomerase-targeting drugs.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.007

Oncogenic transformation potentiates apoptosis, S-phase arrest and stress-kinase activation by etoposide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.007

The topoisomerase inhibitors camptothecin and etoposide induce a CD95-independent apoptosis of activated peripheral lymphocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.007

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.007

The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.007

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.007

IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.007

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.007

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.007

Synthetic Smac/DIABLO peptides enhance the effects of chemotherapeutic agents by binding XIAP and cIAP1 in situ

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.007

Direct interaction between survivin and Smac/DIABLO is essential for the anti-apoptotic activity of survivin during taxol-induced apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.007

Proteasome-mediated degradation of Smac during apoptosis: XIAP promotes Smac ubiquitination in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.007

Cellular inhibitor of apoptosis 1 and 2 are ubiquitin ligases for the apoptosis inducer Smac/DIABLO

7 January 2021

1 reference

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Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway

7 January 2021

1 reference

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Apaf-1/cytochrome c-independent and Smac-dependent induction of apoptosis in multiple myeloma (MM) cells

7 January 2021

1 reference

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Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.007

The inhibitor of apoptosis protein-binding domain of Smac is not essential for its proapoptotic activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.007

Generation and characterization of Smac/DIABLO-deficient mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.007

A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.007

Defective caspase-3 relocalization in non-small cell lung carcinoma.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.007

Apoptosis-inducing factor (AIF): key to the conserved caspase-independent pathways of cell death?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.007

Mitochondrial dysfunction is an essential step for killing of non-small cell lung carcinomas resistant to conventional treatment

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.007

Analysis of gene function in somatic mammalian cells using small interfering RNAs

7 January 2021

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Expression of inhibitor of apoptosis proteins in small- and non-small-cell lung carcinoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.007

Caspase-2 acts upstream of mitochondria to promote cytochrome c release during etoposide-induced apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.007

Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.007

JNK-dependent release of mitochondrial protein, Smac, during apoptosis in multiple myeloma (MM) cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.007

Role of Smac in human leukaemic cell apoptosis and proliferation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.007

Higher spontaneous apoptotic index in small cell compared with non-small cell lung carcinoma cell lines; lack of correlation with Bcl-2/Bax

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.007

Expression of Smac/DIABLO in ovarian carcinoma cells induces apoptosis via a caspase-9-mediated pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.007

Characterization of a novel and specific inhibitor for the pro-apoptotic protease Omi/HtrA2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.007

Cell-specific induction of apoptosis by microinjection of cytochrome c. Bcl-xL has activity independent of cytochrome c release

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.007

Role of apoptosis in the response of lung carcinomas to anti-cancer treatment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.007

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7 January 2021

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Identifiers

DOI

10.1016/J.YEXCR.2004.04.007

1 reference

21 September 2017

1 reference

PubMed ID

15242764