Rearrangement of snRNA structure during assembly and function of the spliceosome (Q40527449)

21 September 2017

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title

Rearrangement of snRNA structure during assembly and function of the spliceosome (English)

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21 September 2017

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Ares M Jr

1

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PubMed ID

7754032

21 September 2017

Weiser B

series ordinal

2

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21 September 2017

1 January 1995

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Progress in Molecular Biology and Translational Science

21 September 2017

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21 September 2017

50

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21 September 2017

131-159

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Pre-mRNA splicing in yeast

21 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Messenger RNA Splicing in Yeast: Clues to Why the Spliceosome Is a Ribonucleoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Biochemical Mechanisms of Constitutive and Regulated Pre-mRNA Splicing

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Evidence for two active sites in the spliceosome provided by stereochemistry of pre-mRNA splicing

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

A mechanism to enhance mRNA splicing fidelity: the RNA-dependent ATPase Prp16 governs usage of a discard pathway for aberrant lariat intermediates

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

U4 small nuclear RNA dissociates from a yeast spliceosome and does not participate in the subsequent splicing reaction

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Trans-splicing of nematode premessenger RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Conformation of an RNA pseudoknot

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Site-specific cross-linking of mammalian U5 snRNP to the 5' splice site before the first step of pre-mRNA splicing

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Mutations in U6 snRNA that alter splice site specificity: implications for the active site

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Involvement of U6 snRNA in 5' splice site selection

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

A compensatory base change in U1 snRNA suppresses a 5' splice site mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

5' splice site selection in yeast: genetic alterations in base-pairing with U1 reveal additional requirements

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

A U1 snRNA:pre-mRNA base pairing interaction is required early in yeast spliceosome assembly but does not uniquely define the 5' cleavage site.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

The organization of 3' splice-site sequences in mammalian introns

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Mutations at the 3′ splice site can be suppressed by compensatory base changes in U1 snRNA in fission yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Spliced leader RNA sequences can substitute for the essential 5' end of U1 RNA during splicing in a mammalian in vitro system

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Uncoupling two functions of the U1 small nuclear ribonucleoprotein particle during in vitro splicing

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

The 5' splice site consensus RNA oligonucleotide induces assembly of U2/U4/U5/U6 small nuclear ribonucleoprotein complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Disruption of base pairing between the 5' splice site and the 5' end of U1 snRNA is required for spliceosome assembly

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Lethal and temperature-sensitive mutations and their suppressors identify an essential structural element in U2 small nuclear RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Small nuclear ribonucleoprotein (RNP) U2 contains numerous additional proteins and has a bipartite RNP structure under splicing conditions

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Multiple functional domains of human U2 small nuclear RNA: strengthening conserved stem I can block splicing

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

A novel base-pairing interaction between U2 and U6 snRNAs suggests a mechanism for the catalytic activation of the spliceosome

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Mutational analysis of the yeast U2 snRNA suggests a structural similarity to the catalytic core of group I introns

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Efficient association of U2 snRNPs with pre-mRNA requires an essential U2 RNA structural element

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Mutations in an essential U2 small nuclear RNA structure cause cold-sensitive U2 small nuclear ribonucleoprotein function by favoring competing alternative U2 RNA structures

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Antisense probes targeted to an internal domain in U2 snRNP specifically inhibit the second step of pre-mRNA splicing

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Recognition of the TACTAAC box during mRNA splicing in yeast involves base pairing to the U2-like snRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

A compensatory base change in human U2 snRNA can suppress a branch site mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Mammalian pre-mRNA branch site selection by U2 snRNP involves base pairing.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Limited functional equivalence of phylogenetic variation in small nuclear RNA: yeast U2 RNA with altered branchpoint complementarity inhibits splicing and produces a dominant lethal phenotype

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Mammalian U2 snRNP has a sequence-specific RNA-binding activity

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Interactions of small nuclear RNA's with precursor messenger RNA during in vitro splicing

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Unusual branch point selection in processing of human growth hormone pre-mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Splicing of SV40 early pre-mRNA to large T and small t mRNAs utilizes different patterns of lariat branch sites

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Branch nucleophile selection in pre-mRNA splicing: evidence for the bulged duplex model

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Evidence for the existence of snRNAs U4 and U6 in a single ribonucleoprotein complex and for their association by intermolecular base pairing

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

U4 and U6 RNAs coexist in a single small nuclear ribonucleoprotein particle

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Localization of a base-paired interaction between small nuclear RNAs U4 and U6 in intact U4/U6 ribonucleoprotein particles by psoralen cross-linking

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Spliceosomal RNA U6 is remarkably conserved from yeast to mammals

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

U5 small nuclear ribonucleoprotein: RNA structure analysis and ATP-dependent interaction with U4/U6

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Architecture of the U5 small nuclear RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Three novel functional variants of human U5 small nuclear RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Evidence for base-pairing between mammalian U2 and U6 small nuclear ribonucleoprotein particles

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Genetic evidence for base pairing between U2 and U6 snRNA in mammalian mRNA splicing

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Base pairing between U2 and U6 snRNAs is necessary for splicing of a mammalian pre-mRNA

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

In vitro assembly of yeast U6 snRNP: a functional assay

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Multiple roles for U6 snRNA in the splicing pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Human U2 snRNA can function in pre-mRNA splicing in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

A base-pairing interaction between U2 and U6 small nuclear RNAs occurs in > 150S complexes in HeLa cell extracts: implications for the spliceosome assembly pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Association of U6 snRNA with the 5'-splice site region of pre-mRNA in the spliceosome

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Evidence for a base-pairing interaction between U6 small nuclear RNA and 5' splice site during the splicing reaction in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Conformational changes of U6 RNA during the spliceosome cycle: an intramolecular helix is essential both for initiating the U4-U6 interaction and for the first step of slicing

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

A stem/loop in U6 RNA defines a conformational switch required for pre-mRNA splicing

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Suppressors of a U4 snRNA mutation define a novel U6 snRNP protein with RNA-binding motifs

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

The phylogenetically invariant ACAGAGA and AGC sequences of U6 small nuclear RNA are more tolerant of mutation in human cells than in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Splicing function of mammalian U6 small nuclear RNA: conserved positions in central domain and helix I are essential during the first and second step of pre-mRNA splicing

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Mutations in yeast U5 snRNA alter the specificity of 5' splice-site cleavage

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

U5 snRNA interacts with exon sequences at 5′ and 3′ splice sites

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Two domains of yeast U6 small nuclear RNA required for both steps of nuclear precursor messenger RNA splicing

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Randomization-selection analysis of snRNAs in vivo: evidence for a tertiary interaction in the spliceosome

1 reference

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7 January 2021

Evidence for an essential non-Watson–Crick interaction between the first and last nucleotides of a nuclear pre-mRNA intron

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

Requirement of the RNA helicase-like protein PRP22 for release of messenger RNA from spliceosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

mRNA splicing and autocatalytic introns: distant cousins or the products of chemical determinism?

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

How many catalytic RNAs? Ions and the Cheshire cat conjecture.

1 reference

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7 January 2021

Ribozymes: a distinct class of metalloenzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

A general two-metal-ion mechanism for catalytic RNA

1 reference

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7 January 2021

Phosphorothioate substitution identifies phosphate groups important for pre-mRNA splicing

1 reference

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7 January 2021

Split genes and RNA splicing

1 reference

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7 January 2021

RNA-RNA interactions in the spliceosome: unraveling the ties that bind

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2808%2960813-2

7 January 2021

10.1016/S0079-6603(08)60813-2

Identifiers

DOI

0 references

PubMed ID

7754032

1 reference

PubMed ID

7754032