Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death (Q40520566)

21 September 2017

Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death (English)

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21 September 2017

endoplasmic reticulum

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1 reference

Ping Hu

1

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21 September 2017

Zhang Han

series ordinal

2

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21 September 2017

Anthony D Couvillon

series ordinal

3

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21 September 2017

John H Exton

series ordinal

4

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21 September 2017

language of work or name

English

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publication date

31 August 2004

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Journal of Biological Chemistry

21 September 2017

10

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based on heuristic

inferred from page(s)

published in

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21 September 2017

279

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21 September 2017

49420-49429

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21 September 2017

47

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Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

21 September 2017

1 reference

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Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response

21 January 2018

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An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin

21 January 2018

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Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival

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Hepatitis C virus suppresses the IRE1-XBP1 pathway of the unfolded protein response

21 January 2018

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Proteasome inhibitors as new anticancer drugs

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The unfolded protein response

21 January 2018

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Regulation of apoptosis by endoplasmic reticulum pathways.

21 January 2018

1 reference

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Perk is essential for translational regulation and cell survival during the unfolded protein response

21 January 2018

1 reference

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Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction

21 January 2018

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Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation

21 January 2018

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Apoptosis: a link between cancer genetics and chemotherapy

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Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

21 January 2018

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Central role of glycogen synthase kinase-3beta in endoplasmic reticulum stress-induced caspase-3 activation

21 January 2018

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Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway

21 January 2018

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Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death

21 January 2018

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TL1A-induced NF-kappaB activation and c-IAP2 production prevent DR3-mediated apoptosis in TF-1 cells

21 January 2018

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A novel role for XIAP in copper homeostasis through regulation of MURR1

21 January 2018

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Biliverdin reductase: a major physiologic cytoprotectant

21 January 2018

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Cellular survival: a play in three Akts

21 January 2018

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Integrin (alpha 6 beta 4) regulation of eIF-4E activity and VEGF translation: a survival mechanism for carcinoma cells

21 January 2018

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Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy

21 January 2018

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TSC2 mediates cellular energy response to control cell growth and survival

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Role of phospholipase D1 in the regulation of mTOR activity by lysophosphatidic acid

21 January 2018

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The Drosophila gene hid is a direct molecular target of Ras-dependent survival signaling

21 January 2018

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Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

21 January 2018

1 reference

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ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

21 January 2018

1 reference

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Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

21 January 2018

1 reference

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A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

21 January 2018

1 reference

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Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis

21 January 2018

1 reference

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Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1

21 January 2018

1 reference

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BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis

21 January 2018

1 reference

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BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress

21 January 2018

1 reference

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Glial cell line-derived neurotrophic factor increases intracellular calcium concentration. Role of calcium/calmodulin in the activation of the phosphatidylinositol 3-kinase pathway.

21 January 2018

1 reference

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Essential role of calcineurin in response to endoplasmic reticulum stress

21 January 2018

1 reference

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TOR, a central controller of cell growth

21 January 2018

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Effect of extracellular signal-regulated kinase on p53 accumulation in response to cisplatin

21 January 2018

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Reciprocal role of ERK and NF-kappaB pathways in survival and activation of osteoclasts

21 January 2018

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Differential roles for alpha(M)beta(2) integrin clustering or activation in the control of apoptosis via regulation of akt and ERK survival mechanisms

21 January 2018

1 reference

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Role of phosphoinositide 3-kinase in activation of ras and mitogen-activated protein kinase by epidermal growth factor

21 January 2018

1 reference

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Apoptosis suppression by Raf-1 and MEK1 requires MEK- and phosphatidylinositol 3-kinase-dependent signals

21 January 2018

1 reference

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The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338

21 January 2018

1 reference

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Regulation of the protein kinase Raf-1 by oncogenic Ras through phosphatidylinositol 3-kinase, Cdc42/Rac and Pak

21 January 2018

1 reference

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PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation

21 January 2018

1 reference

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Phosphorylation and regulation of Raf by Akt (protein kinase B)

21 January 2018

1 reference

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IAP family proteins--suppressors of apoptosis

21 January 2018

1 reference

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Critical function of endogenous XIAP in regulating caspase activation during sympathetic neuronal apoptosis

21 January 2018

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A new internal-ribosome-entry-site motif potentiates XIAP-mediated cytoprotection

21 January 2018

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Translational induction of the inhibitor of apoptosis protein HIAP2 during endoplasmic reticulum stress attenuates cell death and is mediated via an inducible internal ribosome entry site element.

21 January 2018

1 reference

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IAP proteins: blocking the road to death's door

21 January 2018

1 reference

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The anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3- and caspase 9-interacting sites

21 January 2018

1 reference

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NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

21 January 2018

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Inhibition of apoptosis in normal and transformed intestinal epithelial cells by cAMP through induction of inhibitor of apoptosis protein (IAP)-2

21 January 2018

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Fibroblast growth factor 2-mediated translational control of IAPs blocks mitochondrial release of Smac/DIABLO and apoptosis in small cell lung cancer cells

21 January 2018

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Akt phosphorylation and stabilization of X-linked inhibitor of apoptosis protein (XIAP).

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M407700200

1 reference

21 September 2017

1 reference