K+ Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria (Q40499822)

21 September 2017

K+ Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria (English)

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21 September 2017

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19

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21 September 2017

20

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21 September 2017

Claudia Traidl-Hoffmann

21

Claudia Traidl-Hoffmann

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Marc Schmidt-Supprian

17

Marc Schmidt-Supprian

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Giovanni Magnani

Giovanni Magnani

11

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Ritu Mishra

Ritu Mishra

2

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Sabine Schneider

Sabine Schneider

25

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Guillaume Médard

Guillaume Médard

4

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Matthew A. Cooper

Matthew A Cooper

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Jürgen Ruland

Jürgen Ruland

24

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Bruce Beutler

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Bruce Beutler

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21 September 2017

Olaf Groß

27

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Fabiana Perocchi

26

Fabiana Perocchi

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21 September 2017

Christina J Groß

1

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21 September 2017

Katharina S Schneider

3

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21 September 2017

Jennifer Wettmarshausen

5

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21 September 2017

Daniela C Dittlein

6

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21 September 2017

Hexin Shi

7

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21 September 2017

Oliver Gorka

8

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21 September 2017

Paul-Albert Koenig

9

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21 September 2017

Stephan Fromm

10

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21 September 2017

Tamara Ćiković

12

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21 September 2017

Lara Hartjes

13

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21 September 2017

Joachim Smollich

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21 September 2017

Avril A B Robertson

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21 September 2017

Marc Schmidt-Supprian

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21 September 2017

Michael Schuster

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21 September 2017

language of work or name

English

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publication date

24 September 2016

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21 September 2017

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45

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4

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21 September 2017

761-773

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A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.

21 September 2017

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

Targeting mitochondria metabolism for cancer therapy

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

Rotenone-induced Impairment of Mitochondrial Electron Transport Chain Confers a Selective Priming Signal for NLRP3 Inflammasome Activation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

Comprehensive measurement of respiratory activity in permeabilized cells using extracellular flux analysis

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

EPI-743 reverses the progression of the pediatric mitochondrial disease--genetically defined Leigh Syndrome.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

Investigating metformin for cancer prevention and treatment: the end of the beginning

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

Tumor-selective induction of apoptosis and the small-molecule immune response modifier imiquimod

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

Nociceptive sensory neurons drive interleukin-23-mediated psoriasiform skin inflammation.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

Optimized chemical proteomics assay for kinase inhibitor profiling.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

How mitochondria produce reactive oxygen species

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

Quantitative production of macrophages or neutrophils ex vivo using conditional Hoxb8.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

Metabolism of inflammation limited by AMPK and pseudo-starvation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

NRH:quinone reductase 2: an enzyme of surprises and mysteries

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

The inflammasome: an integrated view

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

Mitochondrial complex I activity suppresses inflammation and enhances bone resorption by shifting macrophage-osteoclast polarization

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

Hypoxia triggers subcellular compartmental redox signaling in vascular smooth muscle cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

A role for mitochondria in NLRP3 inflammasome activation

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

Inhibiting the Inflammasome: A Chemical Perspective.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

Features of idebenone and related short-chain quinones that rescue ATP levels under conditions of impaired mitochondrial complex I

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

Inflammasome activation and inhibition in primary murine bone marrow-derived cells, and assays for IL-1α, IL-1β, and caspase-1.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

Free radicals and antioxidants in normal physiological functions and human disease

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-8 is required for inflammasome priming

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

NQO2 is a reactive oxygen species generating off-target for acetaminophen.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

Caspase-11 activates a canonical NLRP3 inflammasome by promoting K(+) efflux

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

A mitochondrial etiology of Alzheimer and Parkinson disease

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

A novel Cre recombinase reporter mouse strain facilitates selective and efficient infection of primary immune cells with adenoviral vectors

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

Gout-associated uric acid crystals activate the NALP3 inflammasome

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

K⁺ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.IMMUNI.2016.08.010

Identifiers

DOI

10.1016/J.IMMUNI.2016.08.010

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release_amfjzcginvd6pl5bwephip6wdu

21 September 2017

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https://api.fatcat.wiki/v0/release/amfjzcginvd6pl5bwephip6wdu

Fatcat

reference URL

mapped directly with Wikidata item

24 November 2022

based on heuristic

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