Solution structure of prosurvival Mcl-1 and characterization of its binding by proapoptotic BH3-only ligands. (Q40490346)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15550399%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

title

Solution structure of prosurvival Mcl-1 and characterization of its binding by proapoptotic BH3-only ligands (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15550399%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15550399%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Sarah Richardson

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15550399%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

David C Huang

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15550399%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

author name string

Lin Chen

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15550399%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Penny J Harrison

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15550399%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Mark G Hinds

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15550399%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

language of work or name

English

0 references

publication date

18 November 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15550399%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

5 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15550399%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

volume

280

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15550399%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

page(s)

4738-4744

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15550399%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15550399%20AND%20SRC:MED&resulttype=core&format=json

Cell death: critical control points

5 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

The Bcl-2 family: roles in cell survival and oncogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

BH3-Only proteins-essential initiators of apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

Myeloid cell factor-1 is a critical survival factor for multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

Regulation of Bcl-2-family proteins in myeloma cells by three myeloma survival factors: interleukin-6, interferon-alpha and insulin-like growth factor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

Granulocyte macrophage colony-stimulating factor signaling and proteasome inhibition delay neutrophil apoptosis by increasing the stability of Mcl-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

Bad-deficient mice develop diffuse large B cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

Proapoptotic BH3-only proteins trigger membrane integration of prosurvival Bcl-w and neutralize its activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

Solution structure and mutagenesis of the caspase recruitment domain (CARD) from Apaf-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

Bcl-2 family members do not inhibit apoptosis by binding the caspase activator Apaf-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

Bim: a novel member of the Bcl-2 family that promotes apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

Bcl-2, Bcl-XL and adenovirus protein E1B19kD are functionally equivalent in their ability to inhibit cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

The structure of Bcl-w reveals a role for the C-terminal residues in modulating biological activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

The program XEASY for computer-supported NMR spectral analysis of biological macromolecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

Protein backbone angle restraints from searching a database for chemical shift and sequence homology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

Torsion angle dynamics for NMR structure calculation with the new program DYANA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

The Xplor-NIH NMR molecular structure determination package

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

Influence of non-bonded parameters on the quality of NMR structures: a new force field for NMR structure calculation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

MOLMOL: a program for display and analysis of macromolecular structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

Rationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

Solution structure of the antiapoptotic protein bcl-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

Unique structural features of a BCL-2 family protein CED-9 and biophysical characterization of CED-9/EGL-1 interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

Structural, biochemical, and functional analyses of CED-9 recognition by the proapoptotic proteins EGL-1 and CED-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

Solution structure of human BCL-w: modulation of ligand binding by the C-terminal helix

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

The structure of a Bcl-xL/Bim fragment complex: implications for Bim function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

Mouse models of cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

The intracellular distribution and pattern of expression of Mcl-1 overlap with, but are not identical to, those of Bcl-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

Structure of Bax: coregulation of dimer formation and intracellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

Heteronuclear multidimensional NMR experiments for the structure determination of proteins in solution employing pulsed field gradients

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411434200

21 January 2018

Identifiers

DOI

10.1074/JBC.M411434200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15550399%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

1 reference