RIPK1 inhibits ZBP1-driven necroptosis during development (Q40486619)

20 September 2017

RIPK1 inhibits ZBP1-driven necroptosis during development (English)

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Receptor (TNFRSF)-interacting serine-threonine kinase 1

20 September 2017

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GOA release 2020-03-11

Z-DNA binding protein 1

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GOA release 2020-03-11

author

Andreas Strasser

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20 September 2017

Søren Warming

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Merone Roose-Girma

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object named as

Merone Roose-Girma

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20 September 2017

Kim Newton

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20 September 2017

Katherine E Wickliffe

2

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20 September 2017

Allie Maltzman

3

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20 September 2017

Debra L Dugger

4

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20 September 2017

Victoria C Pham

6

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20 September 2017

Jennie R Lill

7

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20 September 2017

Margaret Solon

10

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20 September 2017

Hai Ngu

11

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20 September 2017

Joshua D Webster

12

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20 September 2017

Vishva M Dixit

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20 September 2017

language of work or name

English

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publication date

7 November 2016

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20 September 2017

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20 September 2017

540

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20 September 2017

7631

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20 September 2017

129-133

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https://scigraph.springernature.com/pub.10.1038/nature20559

20 September 2017

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cites work

Activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis

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12 December 2020

Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation

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12 December 2020

RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis

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12 December 2020

RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition

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12 December 2020

Distinct roles of RIP1-RIP3 hetero- and RIP3-RIP3 homo-interaction in mediating necroptosis

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12 December 2020

RIPK1 blocks early postnatal lethality mediated by caspase-8 and RIPK3

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12 December 2020

RIPK1 can function as an inhibitor rather than an initiator of RIPK3-dependent necroptosis

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12 December 2020

The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism

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12 December 2020

The death domain kinase RIP mediates the TNF-induced NF-kappaB signal

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12 December 2020

Receptor-interacting protein homotypic interaction motif-dependent control of NF-kappa B activation via the DNA-dependent activator of IFN regulatory factors

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12 December 2020

Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses

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12 December 2020

Cutting edge: RIPK1 Kinase inactive mice are viable and protected from TNF-induced necroptosis in vivo

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12 December 2020

RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis.

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12 December 2020

The function of TRADD in signaling through tumor necrosis factor receptor 1 and TRIF-dependent Toll-like receptors

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12 December 2020

DAI/ZBP1/DLM-1 complexes with RIP3 to mediate virus-induced programmed necrosis that is targeted by murine cytomegalovirus vIRA.

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12 December 2020

Necroptosis and Inflammation

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12 December 2020

Diverse sequence determinants control human and mouse receptor interacting protein 3 (RIP3) and mixed lineage kinase domain-like (MLKL) interaction in necroptotic signaling

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12 December 2020

ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways

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12 December 2020

Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies

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12 December 2020

Caspase-8 deficiency in T cells leads to a lethal lymphoinfiltrative immune disorder

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12 December 2020

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

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12 December 2020

cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination

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12 December 2020

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

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12 December 2020

c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation

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12 December 2020

Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha

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12 December 2020

TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines

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12 December 2020

Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3.

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12 December 2020

RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis

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12 December 2020

RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis.

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12 December 2020

RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis.

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12 December 2020

IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis

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12 December 2020

Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO

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12 December 2020

Identifiers

DOI

10.1038/NATURE20559

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Dimensions Publication ID

20 September 2017

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