Distinct roles of RIP1-RIP3 hetero- and RIP3-RIP3 homo-interaction in mediating necroptosis (Q28654331)

2

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X-K Wang

3

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Y Zhang

4

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H Wan

5

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Y Song

6

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X Chen

7

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J Shao

8

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J Han

Cell Death & Differentiation

9

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language of work or name

English

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publication date

November 2014

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published in

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volume

21

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page(s)

1709-20

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issue

11

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cites work

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The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism

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Diverse sequence determinants control human and mouse receptor interacting protein 3 (RIP3) and mixed lineage kinase domain-like (MLKL) interaction in necroptotic signaling

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Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium

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The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis

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Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase

17 March 2017

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Caspase 8 inhibits programmed necrosis by processing CYLD

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FADD: an endogenous inhibitor of RIP3-driven regulated necrosis

17 March 2017

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Complementary roles of Fas-associated death domain (FADD) and receptor interacting protein kinase-3 (RIPK3) in T-cell homeostasis and antiviral immunity

17 March 2017

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cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms

17 March 2017

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Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis

17 March 2017

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cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production

17 March 2017

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DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF-kappaB

17 March 2017

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Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation

17 March 2017

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Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha

17 March 2017

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RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis

17 March 2017

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Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

17 March 2017

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Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

17 March 2017

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Molecular mechanisms of necroptosis: an ordered cellular explosion

17 March 2017

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Identification of RIP1 kinase as a specific cellular target of necrostatins

7 April 2017

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RIP3 mediates the embryonic lethality of caspase-8-deficient mice

7 April 2017

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RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis.

7 April 2017

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Widespread mitochondrial depletion via mitophagy does not compromise necroptosis

3 June 2018

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Toll-like receptor 3-mediated necrosis via TRIF, RIP3, and MLKL.

3 June 2018

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RIP3: a molecular switch for necrosis and inflammation

3 June 2018

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Interferon-induced RIP1/RIP3-mediated necrosis requires PKR and is licensed by FADD and caspases

3 June 2018

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Caspase blockade induces RIP3-mediated programmed necrosis in Toll-like receptor-activated microglia.

3 June 2018

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RIP1-driven autoinflammation targets IL-1α independently of inflammasomes and RIP3.

3 June 2018

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TNF can activate RIPK3 and cause programmed necrosis in the absence of RIPK1.

3 June 2018

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New components of the necroptotic pathway

3 June 2018

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3 June 2018

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Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis

3 June 2018

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RIP3 finds partners in crime

3 June 2018

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Rip1 (receptor-interacting protein kinase 1) mediates necroptosis and contributes to renal ischemia/reperfusion injury

3 June 2018

1 reference

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Programmed necrosis: backup to and competitor with apoptosis in the immune system

3 June 2018

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Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis.

3 June 2018

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The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs

3 June 2018

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3 June 2018

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Functional complementation between FADD and RIP1 in embryos and lymphocytes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211369

zVAD-induced necroptosis in L929 cells depends on autocrine production of TNFα mediated by the PKC-MAPKs-AP-1 pathway.

3 June 2018

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3 June 2018

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3 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211369

Necroptosis, necrosis and secondary necrosis converge on similar cellular disintegration features.

3 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211369

Error bars in experimental biology

3 June 2018

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Regulation of endogenous gene expression with a small-molecule dimerizer

3 June 2018

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Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211369

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3 June 2018

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RIP kinase-dependent necrosis drives lethal systemic inflammatory response syndrome

3 June 2018

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FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation.

21 January 2018

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https://api.crossref.org/works/10.1038%2FCDD.2014.77

Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation.

21 January 2018

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A role of RIP3-mediated macrophage necrosis in atherosclerosis development.

21 January 2018

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Multiple death pathways in TNF-treated fibroblasts: RIP3- and RIP1-dependent and independent routes.

21 January 2018

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21 January 2018

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Cell death: A killer puts a stop on necroptosis

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/24902902

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/CDD.2014.77

1 reference

2287631

2287631

1 reference

1 reference

1 reference