The C-terminal sterile alpha motif and the extreme C terminus regulate the transcriptional activity of the alpha isoform of p73. (Q40446389)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15769743%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

title

The C-terminal sterile alpha motif and the extreme C terminus regulate the transcriptional activity of the alpha isoform of p73 (English)

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9 January 2020

1

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9 January 2020

author name string

Xinbin Chen

series ordinal

2

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9 January 2020

language of work or name

English

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publication date

15 March 2005

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15769743%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

9 January 2020

number of pages

9

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based on heuristic

inferred from page(s)

published in

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9 January 2020

volume

280

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9 January 2020

page(s)

20111-20119

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9 January 2020

issue

20

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Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers

9 January 2020

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P63 and P73: P53 mimics, menaces and more

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Two new p73 splice variants, gamma and delta, with different transcriptional activity.

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On the shoulders of giants: p63, p73 and the rise of p53.

21 January 2018

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p53 Family members p63 and p73 are SAM domain-containing proteins

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p73 is a simian [correction of human] p53-related protein that can induce apoptosis

21 January 2018

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Solution structure of a conserved C-terminal domain of p73 with structural homology to the SAM domain.

21 January 2018

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p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours

21 January 2018

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DeltaNp73, a dominant-negative inhibitor of wild-type p53 and TAp73, is up-regulated in human tumors

21 January 2018

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p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

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Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis

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Comparative analysis of p73 and p53 regulation and effector functions

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Induction of p57(KIP2) expression by p73beta.

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p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage

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The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

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Identification and classification of p53-regulated genes

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Role for the p53 homologue p73 in E2F-1-induced apoptosis

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Transactivation-deficient Delta TA-p73 inhibits p53 by direct competition for DNA binding: implications for tumorigenesis.

21 January 2018

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ASPP proteins specifically stimulate the apoptotic function of p53

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ASPP1 and ASPP2: common activators of p53 family members

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Physical interaction with Yes-associated protein enhances p73 transcriptional activity

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Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

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The p53 family: same response, different signals?

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DNA damage activates p53 through a phosphorylation-acetylation cascade

21 January 2018

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p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage

21 January 2018

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p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2.

21 January 2018

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Function of p73, not of p53, is inhibited by the physical interaction with RACK1 and its inhibitory effect is counteracted by pRB.

21 January 2018

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Physical interaction of p73 with c-Myc and MM1, a c-Myc-binding protein, and modulation of the p73 function

21 January 2018

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A C-terminal inhibitory domain controls the activity of p63 by an intramolecular mechanism

21 January 2018

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DeltaNp73beta is active in transactivation and growth suppression.

21 January 2018

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Antioxidants enhance the cytotoxicity of chemotherapeutic agents in colorectal cancer: a p53-independent induction of p21WAF1/CIP1 via C/EBPbeta

21 January 2018

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The activation domains, the proline-rich domain, and the C-terminal basic domain in p53 are necessary for acetylation of histones on the proximal p21 promoter and interaction with p300/CREB-binding protein.

21 January 2018

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21 January 2018

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SAM: a novel motif in yeast sterile and Drosophila polyhomeotic proteins

21 January 2018

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Covalent modification of p73alpha by SUMO-1. Two-hybrid screening with p73 identifies novel SUMO-1-interacting proteins and a SUMO-1 interaction motif

21 January 2018

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Small ubiquitin-like modifier conjugation regulates nuclear export of TEL, a putative tumor suppressor

21 January 2018

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Polymerization of the SAM domain of TEL in leukemogenesis and transcriptional repression

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The N-terminal domain of p73 interacts with the CH1 domain of p300/CREB binding protein and mediates transcriptional activation and apoptosis

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21 January 2018

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21 January 2018

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