Prevention of diabetes by manipulation of anti-IGRP autoimmunity: high efficiency of a low-affinity peptide (Q40418904)

20 September 2017

Prevention of diabetes by manipulation of anti-IGRP autoimmunity: high efficiency of a low-affinity peptide (English)

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20 September 2017

6

Leah Edelstein-Keshet

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20 September 2017

Athanasius F. M. Marée

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object named as

Athanasius F M Marée

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20 September 2017

Bingye Han

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20 September 2017

Pau Serra

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20 September 2017

Abdelaziz Amrani

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20 September 2017

Jun Yamanouchi

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20 September 2017

Pere Santamaria

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20 September 2017

language of work or name

English

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publication date

22 May 2005

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20 September 2017

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645-652

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20 September 2017

6

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https://scigraph.springernature.com/pub.10.1038/nm1250

20 September 2017

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cites work

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No effect of oral insulin on residual beta-cell function in recent-onset type I diabetes (the IMDIAB VII). IMDIAB Group.

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Effector lymphocytes in autoimmunity

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A comprehensive guide to antibody and T-cell responses in type 1 diabetes.

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Major histocompatibility complex class I-restricted T cells are required for all but the end stages of diabetes development in nonobese diabetic mice and use a prevalent T cell receptor alpha chain gene rearrangement

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Prevalent CD8(+) T cell response against one peptide/MHC complex in autoimmune diabetes

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Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes.

21 January 2018

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Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood

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Cloning and characterization of the human and rat islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP) genes

21 January 2018

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Genetics of type 1 diabetes mellitus

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Peptide-induced T-cell tolerance to prevent autoimmune diabetes in a transgenic mouse model

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Peptide vaccination can lead to enhanced tumor growth through specific T-cell tolerance induction.

21 January 2018

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Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library.

21 January 2018

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Kinetics of peptide uptake and tissue distribution following a single intranasal dose of peptide

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Selective expansion of high- or low-avidity cytotoxic T lymphocytes and efficacy for adoptive immunotherapy.

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Intensity of the vaccine-elicited immune response determines tumor clearance

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Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health

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High vaccination efficiency of low-affinity epitopes in antitumor immunotherapy.

21 January 2018

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Induction of a non-encephalitogenic type 2 T helper-cell autoimmune responsein multiple sclerosis after administration of an altered peptide ligand ina placebo-controlled, randomized phase II trial

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Progression of autoimmune diabetes driven by avidity maturation of a T-cell population

21 January 2018

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Expansion of the Antigenic Repertoire of a Single T Cell Receptor upon T Cell Activation

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Inhibition of experimental autoimmune encephalomyelitis by inhalation but not oral administration of the encephalitogenic peptide: influence of MHC binding affinity

21 January 2018

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7 January 2021

Affinity for class II MHC determines the extent to which soluble peptides tolerize autoreactive T cells in naive and primed adult mice--implications for autoimmunity

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7 January 2021

Hierarchy in the ability of T cell epitopes to induce peripheral tolerance to antigens from myelin

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7 January 2021

Effects of oral administration of type II collagen on rheumatoid arthritis

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7 January 2021

Lack of efficacy of oral bovine type II collagen added to existing therapy in rheumatoid arthritis

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7 January 2021

Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligand

1 reference

7 January 2021

An altered peptide ligand mediates immune deviation and prevents autoimmune encephalomyelitis

1 reference

7 January 2021

Identifiers

DOI

10.1038/NM1250

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Dimensions Publication ID

20 September 2017

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