A comprehensive guide to antibody and T-cell responses in type 1 diabetes. (Q35583448)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14617043%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

review article

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title

A comprehensive guide to antibody and T-cell responses in type 1 diabetes (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14617043%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

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1

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21 December 2019

author name string

T P DiLorenzo

series ordinal

2

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21 December 2019

language of work or name

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1 November 2003

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21 December 2019

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21 December 2019

volume

62

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21 December 2019

issue

5

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21 December 2019

page(s)

359-377

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Exophthalmic goiter in children

21 December 2019

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Molecular cloning of phogrin, a protein-tyrosine phosphatase homologue localized to insulin secretory granule membranes

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Definition of multiple ICA512/phogrin autoantibody epitopes and detection of intramolecular epitope spreading in relatives of patients with type 1 diabetes

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Identification and cloning of a granule autoantigen (carboxypeptidase-H) associated with type I diabetes

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Antibodies against different epitopes of heat-shock protein 60 in children with type 1 diabetes mellitus.

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Islet cell autoantigen 69 kD (ICA69). Molecular cloning and characterization of a novel diabetes-associated autoantigen

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HLA-associated inverse correlation between T cell and antibody responsiveness to islet autoantigen in recent-onset insulin-dependent diabetes mellitus

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Characterization of human DNA topoisomerase II as an autoantigen recognized by patients with IDDM.

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7 January 2021

T cells and autoantibodies to human HSP70 in type 1 diabetes in children

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Type 1 diabetes alters anti-hsp90 autoantibody isotype

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Autoantibodies to the GLUT-2 glucose transporter of beta cells in insulin-dependent diabetes mellitus of recent onset

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7 January 2021

Transcription factor jun-B is target of autoreactive T-cells in IDDM.

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7 January 2021

Sex-determining region Y-related protein SOX13 is a diabetes autoantigen expressed in pancreatic islets

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7 January 2021

Identification and characterization of glima 38, a glycosylated islet cell membrane antigen, which together with GAD65 and IA2 marks the early phases of autoimmune response in type 1 diabetes.

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7 January 2021

Sulphatide and sulphatide antibodies in insulin-dependent diabetes mellitus

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Autoimmunity to the GM2-1 islet ganglioside before and at the onset of type I diabetes

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7 January 2021

Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice.

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Identification and modulation of a naturally processed T cell epitope from the diabetes-associated autoantigen human glutamic acid decarboxylase 65 (hGAD65).

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Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes.

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

T-cell reactivity to GAD65 peptide sequences shared with coxsackie virus protein in recent-onset IDDM, post-onset IDDM patients and control subjects

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7 January 2021

Identification of naturally processed T cell epitopes from glutamic acid decarboxylase presented in the context of HLA-DR alleles by T lymphocytes of recent onset IDDM patients

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7 January 2021

Glutamic acid decarboxylase T lymphocyte responses associated with susceptibility or resistance to type I diabetes: analysis in disease discordant human twins, non-obese diabetic mice and HLA-DQ transgenic mice

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7 January 2021

Detection of GAD65-specific T-cells by major histocompatibility complex class II tetramers in type 1 diabetic patients and at-risk subjects

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7 January 2021

Insights into autoimmunity gained from structural analysis of MHC-peptide complexes

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7 January 2021

Naturally processed T cell epitopes from human glutamic acid decarboxylase identified using mice transgenic for the type 1 diabetes-associated human MHC class II allele, DRB1*0401.

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7 January 2021

Identification of immunodominant T cell epitopes of human glutamic acid decarboxylase 65 by using HLA-DR(alpha1*0101,beta1*0401) transgenic mice.

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7 January 2021

Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from NOD mice

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7 January 2021

A disease-associated cellular immune response in type 1 diabetics to an immunodominant epitope of insulin

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7 January 2021

T cell response to preproinsulin I and II in the nonobese diabetic mouse

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7 January 2021

Evidence that a peptide spanning the B-C junction of proinsulin is an early Autoantigen epitope in the pathogenesis of type 1 diabetes

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7 January 2021

T cell epitopes of insulin defined in HLA-DR4 transgenic mice are derived from preproinsulin and proinsulin

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7 January 2021

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T-cell epitopes in type 1 diabetes autoantigen tyrosine phosphatase IA-2: potential for mimicry with rotavirus and other environmental agents

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T-cell lines reactive to an immunodominant epitope of the tyrosine phosphatase-like autoantigen IA-2 in type 1 diabetes

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7 January 2021

Early Th1 response in unprimed nonobese diabetic mice to the tyrosine phosphatase-like insulinoma-associated protein 2, an autoantigen in type 1 diabetes

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7 January 2021

Vaccination against autoimmune mouse diabetes with a T-cell epitope of the human 65-kDa heat shock protein.

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7 January 2021

NOD mouse diabetes: the ubiquitous mouse hsp60 is a beta-cell target antigen of autoimmune T cells

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T cell proliferative responses of type 1 diabetes patients and healthy individuals to human hsp60 and its peptides

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7 January 2021

Beta-cell function in new-onset type 1 diabetes and immunomodulation with a heat-shock protein peptide (DiaPep277): a randomised, double-blind, phase II trial

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7 January 2021

Loss of self-tolerance to ICA69 in nonobese diabetic mice

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7 January 2021

Molecular cloning of murine ICA69: diabetes-prone mice recognize the human autoimmune-epitope, Tep69, conserved in splice variants from both species

1 reference

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7 January 2021

ICA69(null) nonobese diabetic mice develop diabetes, but resist disease acceleration by cyclophosphamide.

1 reference

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7 January 2021

Autoimmune islet destruction in spontaneous type 1 diabetes is not beta-cell exclusive.

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7 January 2021

Spontaneous peripheral T-cell responses to the IA-2beta (phogrin) autoantigen in young nonobese diabetic mice

1 reference

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7 January 2021

Imogen 38: a novel 38-kD islet mitochondrial autoantigen recognized by T cells from a newly diagnosed type 1 diabetic patient

1 reference

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7 January 2021

A Reg family protein is overexpressed in islets from a patient with new-onset type 1 diabetes and acts as T-cell autoantigen in NOD mice

1 reference

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7 January 2021

Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library.

1 reference

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7 January 2021

Disabling an integral CTL epitope allows suppression of autoimmune diabetes by intranasal proinsulin peptide

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7 January 2021

Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood

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7 January 2021

Peptide-specific cytotoxicity of T lymphocytes against glutamic acid decarboxylase and insulin in type 1 diabetes mellitus

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7 January 2021

A pancreatic beta-cell-specific homolog of glucose-6-phosphatase emerges as a major target of cell-mediated autoimmunity in diabetes

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7 January 2021

Identification of a -Cell-Specific HLA Class I Restricted Epitope in Type 1 Diabetes

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7 January 2021

Cytotoxic T cells specific for glutamic acid decarboxylase in autoimmune diabetes

1 reference

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7 January 2021

MHC class I-restricted determinants on the glutamic acid decarboxylase 65 molecule induce spontaneous CTL activity

1 reference

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7 January 2021

Cytotoxic T cells to an epitope in the islet autoantigen IA-2 are not disease-specific

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7 January 2021

Acceleration of type 1 diabetes mellitus in proinsulin 2-deficient NOD mice

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7 January 2021

Differential splicing of the IA-2 mRNA in pancreas and lymphoid organs as a permissive genetic mechanism for autoimmunity against the IA-2 type 1 diabetes autoantigen

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7 January 2021

Quantitating protein synthesis, degradation, and endogenous antigen processing

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7 January 2021

Insulin-specific T cells are a predominant component of islet infiltrates in pre-diabetic NOD mice

1 reference

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7 January 2021

During the early prediabetic period in NOD mice, the pathogenic CD8(+) T-cell population comprises multiple antigenic specificities

1 reference

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7 January 2021

Major DQ8-restricted T-cell epitopes for human GAD65 mapped using human CD4, DQA1*0301, DQB1*0302 transgenic IA(null) NOD mice

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7 January 2021

Detection of glutamic acid decarboxylase-activated T cells with I-Ag7 tetramers

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7 January 2021

GAD-reactive CD4+ Th1 cells induce diabetes in NOD/SCID mice.

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7 January 2021

Treatment of NOD diabetes with a novel peptide of the hsp60 molecule induces Th2-type antibodies

1 reference

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7 January 2021

HLA-DQ8 transgenic and NOD mice recognize different epitopes within the cytoplasmic region of the tyrosine phosphatase-like molecule, IA-2.

1 reference

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7 January 2021

T-cell epitope analysis on the autoantigen phogrin (IA-2beta) in the nonobese diabetic mouse

1 reference

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7 January 2021

10.1034/J.1399-0039.2003.00152.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14617043%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference