Atypical protein kinase Ciota plays a critical role in human lung cancer cell growth and tumorigenicity (Q40402576)

20 September 2017

Atypical protein kinase Ciota plays a critical role in human lung cancer cell growth and tumorigenicity (English)

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20 September 2017

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Roderick P Regala

1

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20 September 2017

Capella Weems

2

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20 September 2017

Lee Jamieson

3

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20 September 2017

John A Copland

4

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20 September 2017

E Aubrey Thompson

5

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20 September 2017

Alan P Fields

6

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20 September 2017

language of work or name

English

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publication date

1 July 2005

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Journal of Biological Chemistry

20 September 2017

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20 September 2017

280

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20 September 2017

31109-31115

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20 September 2017

35

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https://api.crossref.org/works/10.1074%2FJBC.M505402200

20 September 2017

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Current standards of care in small-cell and non-small-cell lung cancer

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505402200

Molecular abnormalities in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

Reversion of Ras- and phosphatidylcholine-hydrolyzing phospholipase C-mediated transformation of NIH 3T3 cells by a dominant interfering mutant of protein kinase C lambda is accompanied by the loss of constitutive nuclear mitogen-activated protein k

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

Evidence that atypical protein kinase C-lambda and atypical protein kinase C-zeta participate in Ras-mediated reorganization of the F-actin cytoskeleton.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

Atypical protein kinases Clambda and -zeta associate with the GTP-binding protein Cdc42 and mediate stress fiber loss

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505402200

Bcr-Abl regulates protein kinase Ciota (PKCiota) transcription via an Elk1 site in the PKCiota promoter.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505402200

An essential role for Rac in Ras transformation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505402200

Requirement of NF-kappaB activation to suppress p53-independent apoptosis induced by oncogenic Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

Implication of atypical protein kinase C isozymes lambda and zeta in Ras mediated reorganization of the actin cytoskeleton and cyclin D1-induction

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505402200

Protein kinase Ciota is required for Ras transformation and colon carcinogenesis in vivo

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505402200

Protein kinase C betaII and TGFbetaRII in omega-3 fatty acid-mediated inhibition of colon carcinogenesis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505402200

Role of cyclooxygenase 2 in protein kinase C beta II-mediated colon carcinogenesis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505402200

Protein kinase C (PKC) betaII induces cell invasion through a Ras/Mek-, PKC iota/Rac 1-dependent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505402200

NF-kappaB/RelA transactivation is required for atypical protein kinase C iota-mediated cell survival.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505402200

Protein kinase Ciota activity is necessary for Bcr-Abl-mediated resistance to drug-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

Inhibition of anchorage-independent growth and lung metastasis of A549 lung carcinoma cells by IkappaBbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

Upregulation of Bcl-x and Bfl-1 as a potential mechanism of chemoresistance, which can be overcome by NF-kappaB inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

Dexamethasone and tumor necrosis factor-alpha act together to induce the cellular inhibitor of apoptosis-2 gene and prevent apoptosis in a variety of cell types

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

Cell polarity: Par6, aPKC and cytoskeletal crosstalk

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505402200

Rac-PAK signaling stimulates extracellular signal-regulated kinase (ERK) activation by regulating formation of MEK1-ERK complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

Protein kinase C zeta subspecies from rat brain: its structure, expression, and properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

Primary structure, tissue distribution, and expression of mouse phosphoinositide-dependent protein kinase-1, a protein kinase that phosphorylates and activates protein kinase Czeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

Regulation of protein kinase C zeta by PI 3-kinase and PDK-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

Interaction of protein kinase C zeta with ZIP, a novel protein kinase C-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

Localization of atypical protein kinase C isoforms into lysosome-targeted endosomes through interaction with p62.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

A human homolog of the C. elegans polarity determinant Par-6 links Rac and Cdc42 to PKCzeta signaling and cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

The atypical protein kinase Cs. Functional specificity mediated by specific protein adapters

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

Protein kinase C lambda/iota (PKClambda/iota): a PKC isotype essential for the development of multicellular organisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

Atypical protein kinase C iota protects human leukemia cells against drug-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

Regulation of cell survival by atypical protein kinase C isozymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

Human homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42 to atypical protein kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

Regulation and role of the atypical PKC isoforms in cell survival during tumor transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

The atypical protein kinase C-interacting protein p62 is a scaffold for NF-kappaB activation by nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

Activation of IkappaB kinase beta by protein kinase C isoforms

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M505402200

NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

Targeted deletion of protein kinase C lambda reveals a distribution of functions between the two atypical protein kinase C isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

Targeted disruption of the zetaPKC gene results in the impairment of the NF-kappaB pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

A mammalian PAR-3-PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

A One-Step Method for Protein Estimation in Biological Samples: Nitration of Tyrosine in Nitric Acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M505402200

21 January 2018

Identifiers

DOI

10.1074/JBC.M505402200

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20 September 2017

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