Regulation and role of the atypical PKC isoforms in cell survival during tumor transformation (Q38300315)

1 September 2017

Regulation and role of the atypical PKC isoforms in cell survival during tumor transformation (English)

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1 September 2017

J Moscat

1

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1 September 2017

L Sanz

series ordinal

2

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1 September 2017

P Sanchez

series ordinal

3

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1 September 2017

M T Diaz-Meco

series ordinal

4

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1 September 2017

1 January 2001

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Advances in Enzyme Regulation

1 September 2017

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1 September 2017

41

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1 September 2017

99-120

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Regulation of ceramide production and apoptosis

1 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Evidence for a role of protein kinase C zeta subspecies in maturation of Xenopus laevis oocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Inhibition of protein kinase C zeta subspecies blocks the activation of an NF-kappa B-like activity in Xenopus laevis oocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Protein kinase C zeta isoform is critical for mitogenic signal transduction

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https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Evidence for a role of MEK and MAPK during signal transduction by protein kinase C zeta

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

A dominant negative protein kinase C zeta subspecies blocks NF-kappa B activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

The product of par-4, a gene induced during apoptosis, interacts selectively with the atypical isoforms of protein kinase C

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Stress-activated protein kinases in cardiovascular disease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Protein phosphatase 2A is a critical regulator of protein kinase C zeta signaling targeted by SV40 small t to promote cell growth and NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Interleukin-1beta activates protein kinase C zeta in renal mesangial cells. Potential role in prostaglandin E2 up-regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Protein kinase C-zeta mediates angiotensin II activation of ERK1/2 in vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Evidence for a bifurcation of the mitogenic signaling pathway activated by Ras and phosphatidylcholine-hydrolyzing phospholipase C.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Reversion of Ras- and phosphatidylcholine-hydrolyzing phospholipase C-mediated transformation of NIH 3T3 cells by a dominant interfering mutant of protein kinase C lambda is accompanied by the loss of constitutive nuclear mitogen-activated protein k

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https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Localization of atypical protein kinase C isoforms into lysosome-targeted endosomes through interaction with p62.

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https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Activation of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway by conventional, novel, and atypical protein kinase C isotypes.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Role of diacylglycerol-regulated protein kinase C isotypes in growth factor activation of the Raf-1 protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Lambda-interacting protein, a novel protein that specifically interacts with the zinc finger domain of the atypical protein kinase C isotype lambda/iota and stimulates its kinase activity in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Activation of IkappaB kinase beta by protein kinase C isoforms

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https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

The atypical PKC-interacting protein p62 channels NF-kappaB activation by the IL-1-TRAF6 pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

The NF-kappa B and I kappa B proteins: new discoveries and insights

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Identification and characterization of an IkappaB kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

PKC zeta is a molecular switch in signal transduction of TNF-alpha, bifunctionally regulated by ceramide and arachidonic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

zeta PKC induces phosphorylation and inactivation of I kappa B-alpha in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176

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https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Activation of the heterodimeric IkappaB kinase alpha (IKKalpha)-IKKbeta complex is directional: IKKalpha regulates IKKbeta under both basal and stimulated conditions

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Protein kinase C-theta participates in NF-kappaB activation induced by CD3-CD28 costimulation through selective activation of IkappaB kinase beta

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-kappaB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Determination of the specific substrate sequence motifs of protein kinase C isozymes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

The death domain kinase RIP mediates the TNF-induced NF-kappaB signal

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Interaction of protein kinase C zeta with ZIP, a novel protein kinase C-binding protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Phosphatidylinositol 3-kinase-dependent activation of protein kinase C-zeta in bacterial lipopolysaccharide-treated human monocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

IRAK: a kinase associated with the interleukin-1 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Differential stimulation of PKC phosphorylation of potassium channels by ZIP1 and ZIP2

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Association of the p75 neurotrophin receptor with TRAF6

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Functional interactions of transforming growth factor beta-activated kinase 1 with IkappaB kinases to stimulate NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

MEKK1 activates both IkappaB kinase alpha and IkappaB kinase beta

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Tumor necrosis factor receptor-associated factors (TRAFs)--a family of adapter proteins that regulates life and death

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Structural basis for self-association and receptor recognition of human TRAF2

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Expression and function of the leucine zipper protein Par-4 in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Par-4 is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Fibroblast growth factor-2 suppression of tumor necrosis factor alpha-mediated apoptosis requires Ras and the activation of mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Insulin-like Growth Factor 1 Inhibits Apoptosis Using the Phosphatidylinositol 3′-Kinase and Mitogen-activated Protein Kinase Pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Death receptors: signaling and modulation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

The activation of p38 and apoptosis by the inhibition of Erk is antagonized by the phosphoinositide 3-kinase/Akt pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Activation of nuclear factor-kappaB-dependent transcription by tumor necrosis factor-alpha is mediated through phosphorylation of RelA/p65 on serine 529.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Oncogenic Ha-Ras-induced signaling activates NF-kappaB transcriptional activity, which is required for cellular transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Requirement of NF-kappaB activation to suppress p53-independent apoptosis induced by oncogenic Ras.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Ras signalling and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Cell cycle: routine role for Ras.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Regulation of cell death protease caspase-9 by phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

The Drosophila gene hid is a direct molecular target of Ras-dependent survival signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Ras promotes cell survival in Drosophila by downregulating hid expression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

The downregulation of the pro-apoptotic protein Par-4 is critical for Ras-induced survival and tumor progression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Inactivation of the inhibitory kappaB protein kinase/nuclear factor kappaB pathway by Par-4 expression potentiates tumor necrosis factor alpha-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Control of apoptosis and mitotic spindle checkpoint by survivin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

IAP family proteins--suppressors of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Decreased expression of the pro-apoptotic protein Par-4 in renal cell carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Mutually exclusive expression patterns of Bcl-2 and Par-4 in human prostate tumors consistent with down-regulation of Bcl-2 by Par-4.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Oncogenic Ras inhibits Fas ligand-mediated apoptosis by downregulating the expression of Fas.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Diacylglycerol generated by exogenous phospholipase C activates the mitogen-activated protein kinase pathway independent of Ras- and phorbol ester-sensitive protein kinase C: dependence on protein kinase C-zeta

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

Protein kinase C-zeta mediates NF-kappa B activation in human immunodeficiency virus-infected monocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2571%2800%2900009-1

7 January 2021

10.1016/S0065-2571(00)00009-1

Identifiers

DOI

1 reference

1 September 2017

1 reference