PAK4 functions in tumor necrosis factor (TNF) alpha-induced survival pathways by facilitating TRADD binding to the TNF receptor (Q40361376)

19 September 2017

PAK4 functions in tumor necrosis factor (TNF) alpha-induced survival pathways by facilitating TRADD binding to the TNF receptor (English)

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19 September 2017

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Xiaofan Li

1

1 reference

PubMed ID

16227624

19 September 2017

Audrey Minden

series ordinal

2

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PubMed ID

16227624

19 September 2017

language of work or name

English

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publication date

14 October 2005

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Journal of Biological Chemistry

19 September 2017

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19 September 2017

280

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19 September 2017

50

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19 September 2017

41192-41200

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Tumor necrosis factor signaling.

19 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

Signal transduction by tumor necrosis factor and its relatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

TNF-R1 signaling: a beautiful pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

Cell death: critical control points

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

Apoptosis: programmed cell death at a molecular level

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

Mitochondrial activation of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

Death receptors and melanoma resistance to apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

Actin cytoskeleton organization regulated by the PAK family of protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

p21-activated protein kinase gamma-PAK suppresses programmed cell death of BALB3T3 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

Heat shock stress induces cleavage and activation of PAK2 in apoptotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

p21-activated kinase 1 phosphorylates the death agonist bad and protects cells from apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

p21-Activated kinase 5 (Pak5) localizes to mitochondria and inhibits apoptosis by phosphorylating BAD

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

The serine/threonine kinase PAK4 prevents caspase activation and protects cells from apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

PAK4 Kinase Is Essential for Embryonic Viability and for Proper Neuronal Development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

Activated PAK4 regulates cell adhesion and anchorage-independent growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

Death receptor-induced activation of initiator caspase 8 is antagonized by serine/threonine kinase PAK4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

Requirement for PAK4 in the anchorage-independent growth of human cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

A system for stable expression of short interfering RNAs in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

Tumor Necrosis Factor-induced Nuclear Factor κB Activation Is Impaired in Focal Adhesion Kinase-deficient Fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

Targeted disruption of the gene for the PAK5 kinase in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

The Jun kinase 2 isoform is preferentially required for epidermal growth factor-induced transformation of human A549 lung carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

Inhibition of c-Jun N-terminal kinase 2 expression suppresses growth and induces apoptosis of human tumor cells in a p53-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

Combined deficiency of p50 and cRel in CD4+ T cells reveals an essential requirement for nuclear factor kappaB in regulating mature T cell survival and in vivo function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

Activation of the Raf-1/MAP kinase cascade is not sufficient for Ras transformation of RIE-1 epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

Differential effects of PAK1-activating mutations reveal activity-dependent and -independent effects on cytoskeletal regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

MAPK/ERK overrides the apoptotic signaling from Fas, TNF, and TRAIL receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

The true face of JNK activation in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

Adding facets to TNF signaling. The JNK angle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

Tumor necrosis factor: an apoptosis JuNKie?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

Role of JNK activation in apoptosis: a double-edged sword

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

JNK suppresses apoptosis via phosphorylation of the proapoptotic Bcl-2 family protein BAD

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

The absence of NF-kappaB-mediated inhibition of c-Jun N-terminal kinase activation contributes to tumor necrosis factor alpha-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

p38 MAPK mediates TNF-induced apoptosis in endothelial cells via phosphorylation and downregulation of Bcl-x(L).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

P38 alpha mitogen-activated protein kinase sensitizes cells to apoptosis induced by different stimuli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506884200

21 January 2018

Identifiers

DOI

10.1074/JBC.M506884200

1 reference

19 September 2017

1 reference

PubMed ID

16227624