HIV-1 integrase is capable of targeting DNA to the nucleus via an importin alpha/beta-dependent mechanism. (Q40276999)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16716146%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

title

HIV-1 integrase is capable of targeting DNA to the nucleus via an importin alpha/beta-dependent mechanism (English)

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28 January 2020

2

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28 January 2020

author name string

Anna C Hearps

series ordinal

1

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28 January 2020

language of work or name

English

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publication date

1 September 2006

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28 January 2020

number of pages

10

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inferred from page(s)

published in

Biochemical Journal

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28 January 2020

volume

398

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28 January 2020

issue

3

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28 January 2020

page(s)

475-484

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describes a project that uses

28 January 2020

ImageJ

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11 June 2022

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inferred from PubMed Central ID database lookup

cites work

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Class II integrase mutants with changes in putative nuclear localization signals are primarily blocked at a postnuclear entry step of human immunodeficiency virus type 1 replication

22 September 2017

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Requirement for integrase during reverse transcription of human immunodeficiency virus type 1 and the effect of cysteine mutations of integrase on its interactions with reverse transcriptase.

22 September 2017

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Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains

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22 September 2017

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The karyophilic properties of human immunodeficiency virus type 1 integrase are not required for nuclear import of proviral DNA.

22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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The core and carboxyl-terminal domains of the integrase protein of human immunodeficiency virus type 1 each contribute to nonspecific DNA binding.

22 September 2017

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The nuclear localization signal of the matrix protein of human immunodeficiency virus type 1 allows the establishment of infection in macrophages and quiescent T lymphocytes

22 September 2017

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Association of integrase, matrix, and reverse transcriptase antigens of human immunodeficiency virus type 1 with viral nucleic acids following acute infection

22 September 2017

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22 September 2017

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22 September 2017

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Importin beta recognizes parathyroid hormone-related protein with high affinity and mediates its nuclear import in the absence of importin alpha

25 September 2017

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25 September 2017

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A consensus cAMP-dependent protein kinase (PK-A) site in place of the CcN motif casein kinase II site simian virus 40 large T-antigen confers PK-A-mediated regulation of nuclear import

25 September 2017

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The protein kinase CK2 site (Ser111/112) enhances recognition of the simian virus 40 large T-antigen nuclear localization sequence by importin

25 September 2017

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Productive human immunodeficiency virus type 1 (HIV-1) infection of nonproliferating human monocytes

17 June 2018

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Intramolecular masking of nuclear localization signals: analysis of importin binding using a novel AlphaScreen-based method.

17 June 2018

1 reference

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A synthetic peptide bearing the HIV-1 integrase 161-173 amino acid residues mediates active nuclear import and binding to importin alpha: characterization of a functional nuclear localization signal.

20 August 2018

1 reference

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Intracellular transport of human immunodeficiency virus type 1 integrase

20 August 2018

1 reference

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HIV-1 infection requires a functional integrase NLS.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559465

Characterization of the nuclear import pathway for HIV-1 integrase.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559465

HIV-1 genome nuclear import is mediated by a central DNA flap

20 August 2018

1 reference

12 December 2020

Nuclear protein import using digitonin-permeabilized cells

1 reference

12 December 2020

HIV-1 infection of non-dividing cells

1 reference

12 December 2020

A soluble active mutant of HIV-1 integrase: involvement of both the core and carboxyl-terminal domains in multimerization

1 reference

12 December 2020

Kinetic characterization of the human retinoblastoma protein bipartite nuclear localization sequence (NLS) in vivo and in vitro. A comparison with the SV40 large T-antigen NLS

1 reference

12 December 2020

The translocation of transportin–cargo complexes through nuclear pores is independent of both Ran and energy

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12 December 2020

Identifiers

DOI

10.1042/BJ20060466

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16716146%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16716146%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference