Chemically induced nephrotoxicity: role of metabolic activation (Q40184447)

18 September 2017

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title

Chemically induced nephrotoxicity: role of metabolic activation (English)

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18 September 2017

Rush GF

1

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18 September 2017

Smith JH

series ordinal

2

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18 September 2017

Newton JF

series ordinal

3

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18 September 2017

Hook JB

series ordinal

4

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18 September 2017

language of work or name

English

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publication date

1 January 1984

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Critical Reviews in Toxicology

18 September 2017

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18 September 2017

13

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18 September 2017

99-160

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18 September 2017

2

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Possible mechanism of liver necrosis caused by aromatic organic compounds

18 September 2017

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Chemical reactivity, biotransformation, and toxicity of polychlorinated aliphatic compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Biochemical mechanisms in chemical-induced lung injury: roles of metabolic activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Comparative alterations in extrahepatic drug metabolism by factors known to affect hepatic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

The relative participation of liver microsomal amine oxidase and cytochrome P-450 in N-demethylation reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Ethanol-induced cytochrome P-450: catalytic activity after partial purification

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Isolation and comparison of endoplasmic reticulum membranes and their mixed function oxidase activities from mammalian extrahepatic tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Isolation and properties of intermediates in prostaglandin biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Prostaglandin endoperoxides. Novel transformations of arachidonic acid in human platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Prostaglandins and thromboxanes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Cooxygenation by prostaglandin cyclooxygenase from rabbit inner medulla

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Polycyclic aromatic hydrocarbon oxidation during prostaglandin biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Metabolic activation of 7,8-dihydroxy-7,8-dihydrobenzo[a]-pyrene during prostaglandin biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

The action of paraquat and diquat on the respiration of liver cell fractions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Metabolic activation of nitrofurantoin—possible implications for carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Stereoselective activation of vicinal dihalogen compounds to mutagens by glutathione conjugation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Conjugation and bioactivation of chlorotrifluoroethylene.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

The metabolism of S-(1,2 Dichlorovinyl)-l-cysteine by rat liver mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

In vitro activation of 1,2-dichloroethane by microsomal and cytosolic enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

The role of glutathione conjugation in the mutagenicity of 1,2-dibromoethane.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

The mutagenic effect of 1,2-dichloroethane on Salmonella typhimurium I. Activation through conjugation with glutathion in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

The mutagenic effect of 1,2-dichloroethane on Salmonella typhimurium. II. activation by the isolated perfused rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Health Aspects of Chloroform—A Review

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Chloroform: a review of its metabolism, teratogenic, mutagenic, and carcinogenic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Modification of the effects of chloroform on the rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Chloroform toxicity in mice: correlation of renal and hepatic necrosis with covalent binding of metabolites to tissue macromolecules.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

A comparative study on the irreversible binding of labeled halothane trichlorofluoromethane, chloroform, and carbon tetrachloride to hepatic protein and lipids in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Bioactivation of carbon tetrachloride, chloroform and bromotrichloromethane: Role of cytochrome P-450

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

METABOLISM OF VOLATILE ANASTHETICS. I. CONVERSION IN VIVO OF SEVERAL ANESTHETICS TO 14CO-2 AND CHLORIDE.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

The role of metabolism in chloroform hepatotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

RELATIVE NEPHROTOXIC PROPERTIES OF CHLORINATED METHANE, ETHANE, AND ETHYLENE DERIVATIVES IN MICE.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Teratology studies on orally administered chloroform in the rat and rabbit

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Chloroform toxicity in the mouse: Role of genetic factors and steroids

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Polybrominated biphenyl-induced potentiation of chloroform toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Genetic control of chloroform toxicity in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Deuterium isotope effect in bioactivation and hepatotoxicity of chloroform

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Deuterium isotope effect in in vivo bioactivation of chloroform to phosgene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

HEPATIC DAMAGE AND DEATH FROM OVERDOSE OF PARACETAMOL

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Use of isolated kidney cells for study of drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Acute Renal Failure After Acetaminophen Ingestion

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Metabolic oxidation of acetaminophen (paracetamol) mediated by cytochrome P-450 mixed-function oxidase and prostaglandin endoperoxide synthetase in rabbit kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

The effect of 4-acetamidophenol on prostaglandin synthetase activity in bovine and ram seminal vesicle microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Kidney Lesions Induced in Rats by P-aminophenol

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Comparative Nephrotoxicity of Aspirin and Phenacetin Derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

The nephrotoxicity of p-aminophenol. I. The effect on microsomal cytochromes, glutathione and covalent binding in kidney and liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Comparative metabolic studies of phenacetin and structurally-related compounds in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Metabolism of N-acylated and O-alkylated drugs by the intestinal microflora during anaerobic incubation in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Short-term toxicity and reproduction studies in rats with hexachloro-(1,3)-butadiene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Effects of hexachlorobutadiene (HCBD) on renal function and renal organic ion transport in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Results of a two year chronic toxicity study with hexachlorobutadiene in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Depletion by 1,2-dibromoethane, 1,2-dibromo-3-chloropropane, tris(2,3-dibromopropyl)phosphate, and hexachloro-1,3-butadiene of reduced non-protein sulfhydryl groups in target and non-target organs.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

The cephalosporin C nucleus (7-aminocephalosporanic acid) and some of its derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

CLINICAL TRIAL OF CEPHALORIDINE (CEPORIN), A NEW BROAD-SPECTRUM ANTIBIOTIC DERIVED FROM CEPHALOSPORIN C.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Nephrotoxicity Associated With the Use of Cephaloridine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Acute toxicity of cephaloridine, an antibiotic derived from cephalosporin C.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Relationship between the Transport and Toxicity of Cephalosporins in the Kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

The effect of renal cation transport inhibition on cephaloridine nephrotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Mechanisms of cephalosporin nephrotoxicity: a comparison of cephaloridine and cephaloglycin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Renal and hepatic necrosis after metabolic activation of 2-substituted furans and thiophenes, including furosemide and cephaloridine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Molecular basis for several drug-induced nephropathies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Urinary excretion of chlorothiazide in rats before and after phenobarbitone administration

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

LABORATORY AND CLINICAL RESULTS WITH CEPHALORIDINE

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Role of metabolic activation in the pathogenesis of chemically induced pulmonary disease: mechanism of action of the lung-toxic furan, 4-ipomeanol

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Species and strain differences in target organ alkylation and toxicity by 4-ipomeanol. Predictive value of covalent binding in studies of target organ toxicities by reactive metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Flame-retardant chemicals in textiles

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Renal and testicular damage following dermal application of the flame retardant tris(2,3‐dibromopropyl) phosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

The testicular morphology of individuals exposed to dibromochloropropane

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Toxicologic investigations of 1,2-dibromo-3-chloropropane.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Acute toxicity of 1,2-dibromo-3-chloropropane in the F344 male rat. I. Dose--response relationships and differences in routes of exposure.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Acute toxicity of 1,2-dibromo-3-chloropropane in the F344 male rat. II. Development and repair of the renal, epididymal, testicular, and hepatic lesions.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Mutagenicity of halogenated and oxygenated three‐carbon compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Mechanism of renal necrosis induced by bromobenzene or chlorobenzene.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Metabolic activation and hepatotoxicity. Metabolism of bromobenzene in isolated hypatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Bromobenzene-induced liver necrosis. Protective role of glutathione and evidence for 3,4-bromobenzene oxide as the hepatotoxic metabolite.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Mutagenicity testing of cyclamate and some pesticides in Drosophila melanogaster.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Comparison of somatic mutation rates induced in Tradescantia by chemical and physical mutagens

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Carbon tetrachloride poisoning in man; the mechanisms of renal failure and recovery

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Carbon tetrachloride hepatotoxicity: an example of lethal cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Carbon tetrachloride metabolism in the rabbit

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Critical role of lipid peroxidation in carbon tetrachloride-induced loss of aminopyrine demethylase, cytochrome P-450 and glucose 6-phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Spin-trapping of the trichloromethyl radical produced during enzymic NADPH oxidation in the presence of carbon tetrachloride or bromotrichloromethane

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Mechanism of the microsomal reduction of carbon tetrachloride and halothane.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Carbon tetrachloride activation, lipid peroxidation, and the mixed function oxygenase activity of various rat tissues*1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Free radical damage produced by carbon tetrachloride in the lipids of various rat tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Nitroreduction of 5-nitrofuran derivatives by rat liver xanthine oxidase and reduced nicotinamide adenine dinucleotide phosphate-cytochrome c reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

The role of catalytic superoxide formation in the O2 inhibition of nitroreductase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Superoxide and hydrogen peroxide production and NADPH oxidation stimulated by nitrofurantoin in lung microsomes: Possible implications for toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Covalent binding of trans-stilbene to rat liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

The interorgan metabolism of glutathione

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Glutathione and Related γ-Glutamyl Compounds: Biosynthesis and Utilization

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Glutathione turnover in the kidney; considerations relating to the gamma-glutamyl cycle and the transport of amino acids

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Formation and metabolism of a glutathione-S-conjugate in isolated rat liver and kidney cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

Evidence for the Clara cell as a site of cytochrome P450-dependent mixed-function oxidase activity in lung

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10408448409034079

10.3109/10408448409034079

21 January 2018

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1 reference