Role of Polycomb-group genes in sustaining activities of normal and malignant stem cells (Q40130345)

17 September 2017

Role of Polycomb-group genes in sustaining activities of normal and malignant stem cells (English)

1 reference

17 September 2017

Yoshihiro Takihara

1

1 reference

17 September 2017

30 November 2007

1 reference

International Journal of Hematology

17 September 2017

1 reference

17 September 2017

87

1 reference

17 September 2017

1

1 reference

17 September 2017

25-34

1 reference

https://scigraph.springernature.com/pub.10.1007/s12185-007-0006-y

17 September 2017

0 references

cites work

Adenovirus E1A-regulated transcription factor p120E4F inhibits cell growth and induces the stabilization of the cdk inhibitor p21WAF1.

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS12185-007-0006-Y

A limited role for p16Ink4a and p19Arf in the loss of hematopoietic stem cells during proliferative stress

21 January 2018

1 reference

12 December 2020

Polycomb CBX7 has a unifying role in cellular lifespan

1 reference

12 December 2020

Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice

1 reference

12 December 2020

The polycomb group BMI1 gene is a molecular marker for predicting prognosis of chronic myeloid leukemia.

1 reference

12 December 2020

Polycomb group genes as epigenetic regulators of normal and leukemic hemopoiesis

1 reference

12 December 2020

Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation

1 reference

12 December 2020

Locking in stable states of gene expression: transcriptional control during Drosophila development.

1 reference

12 December 2020

The bmi-1 oncoprotein is differentially expressed in non-small cell lung cancer and correlates with INK4A-ARF locus expression

1 reference

12 December 2020

Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias

1 reference

12 December 2020

Loss of the human polycomb group protein BMI1 promotes cancer-specific cell death

1 reference

12 December 2020

A role for mel-18, a Polycomb group-related vertebrate gene, during theanteroposterior specification of the axial skeleton

1 reference

12 December 2020

Repression of the Arf tumor suppressor by E2F3 is required for normal cell cycle kinetics

1 reference

12 December 2020

Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells

1 reference

12 December 2020

Targeted disruption of the mouse homologue of the Drosophila polyhomeotic gene leads to altered anteroposterior patterning and neural crest defects.

1 reference

12 December 2020

Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation

1 reference

12 December 2020

The Polycomb group protein EZH2 directly controls DNA methylation

1 reference

12 December 2020

Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in E mu-myc transgenic mice.

1 reference

12 December 2020

Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene

1 reference

12 December 2020

Tumour stem cells and drug resistance

1 reference

12 December 2020

A trithorax-like gene is interrupted by chromosome 11q23 translocations in acute leukaemias

1 reference

12 December 2020

Polycomb group gene rae28 is required for sustaining activity of hematopoietic stem cells

1 reference

12 December 2020

Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas

1 reference

12 December 2020

Polycomb complexes repress developmental regulators in murine embryonic stem cells

1 reference

12 December 2020

Identification of cooperating oncogenes in E mu-myc transgenic mice by provirus tagging

1 reference

12 December 2020

The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

1 reference

12 December 2020

Altered cellular proliferation and mesoderm patterning in Polycomb-M33-deficient mice.

1 reference

12 December 2020

Linking the Rb and polycomb pathways

1 reference

12 December 2020

Engraftment of immune-deficient mice with human hematopoietic stem cells

1 reference

12 December 2020

Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells

1 reference

12 December 2020

BMI-1 is highly expressed in M0-subtype acute myeloid leukemia.

1 reference

12 December 2020

Expression of Polycomb-group (PcG) protein BMI-1 predicts prognosis in patients with acute myeloid leukemia

1 reference

12 December 2020

Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites

1 reference

12 December 2020

Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells.

1 reference

12 December 2020

The language of covalent histone modifications

1 reference

12 December 2020

Polycomb-group genes and hematopoiesis.

1 reference

12 December 2020

BMI1 is a target gene of E2F-1 and is strongly expressed in primary neuroblastomas

1 reference

12 December 2020

E4F1: a novel candidate factor for mediating BMI1 function in primitive hematopoietic cells

1 reference

12 December 2020

Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF.

1 reference

12 December 2020

Defective long-term repopulating ability in hematopoietic stem cells lacking the Polycomb-group gene rae28.

1 reference

12 December 2020

Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1

1 reference

12 December 2020

Differential impact of Ink4a and Arf on hematopoietic stem cells and their bone marrow microenvironment in Bmi1-deficient mice

1 reference

12 December 2020

Polycomb group genes are required for neural stem cell survival in postembryonic neurogenesis of Drosophila

1 reference

12 December 2020

Polycomb mediates Myc autorepression and its transcriptional control of many loci in Drosophila

1 reference

12 December 2020

EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

1 reference

12 December 2020

Control of developmental regulators by Polycomb in human embryonic stem cells

1 reference

12 December 2020

Stage-specific expression of polycomb group genes in human bone marrow cells

1 reference

12 December 2020

Dynamics of chronic myeloid leukaemia.

1 reference

12 December 2020

Functional antagonism of the Polycomb-Group genes eed and Bmi1 in hemopoietic cell proliferation

1 reference

12 December 2020

Clonogenic cells in acute myeloblastic leukemia

1 reference

12 December 2020

The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion

1 reference

12 December 2020

Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways

1 reference

12 December 2020

Identification of discriminators of hepatoma by gene expression profiling using a minimal dataset approach

1 reference

12 December 2020

The polycomb group protein EZH2 is involved in progression of prostate cancer

1 reference

12 December 2020

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

1 reference

12 December 2020

The cell-cycle regulator geminin inhibits Hox function through direct and polycomb-mediated interactions

1 reference

12 December 2020

The Bmi-1 oncogene induces telomerase activity and immortalizes human mammary epithelial cells

1 reference

12 December 2020

The Bmi-1 oncoprotein is overexpressed in human colorectal cancer and correlates with the reduced p16INK4a/p14ARF proteins

1 reference

12 December 2020

The polycomb-group gene Ezh2 is required for early mouse development

1 reference

12 December 2020

Stabilization of chromatin structure by PRC1, a Polycomb complex

1 reference

12 December 2020

The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene

1 reference

12 December 2020

Epigenetic silencers and Notch collaborate to promote malignant tumours by Rb silencing.

1 reference

12 December 2020

Histone methyltransferase activity of a Drosophila Polycomb group repressor complex

1 reference

12 December 2020

BMI-1 gene amplification and overexpression in hematological malignancies occur mainly in mantle cell lymphomas

1 reference

12 December 2020

Polycomb group gene mel-18 modulates the self-renewal activity and cell cycle status of hematopoietic stem cells

1 reference

12 December 2020

E4F1 is an atypical ubiquitin ligase that modulates p53 effector functions independently of degradation.

1 reference

12 December 2020

Geminin regulates neuronal differentiation by antagonizing Brg1 activity

1 reference

12 December 2020

Role of the polycomb repressive complex 2 in acute promyelocytic leukemia

1 reference

12 December 2020

Role of histone H3 lysine 27 methylation in Polycomb-group silencing

1 reference

12 December 2020

A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells

1 reference

12 December 2020

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

1 reference

12 December 2020

Hypoxia-inducible factors, stem cells, and cancer

1 reference

12 December 2020

Regulation of Hoxb3 expression in the hindbrain and pharyngeal arches by rae28, a member of the mammalian Polycomb group of genes.

1 reference

12 December 2020

pRB family proteins are required for H3K27 trimethylation and Polycomb repression complexes binding to and silencing p16INK4alpha tumor suppressor gene.

1 reference

12 December 2020

The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex

1 reference

12 December 2020

Bmi-1 Regulation of INK4A-ARF Is a Downstream Requirement for Transformation of Hematopoietic Progenitors by E2a-Pbx1

1 reference

12 December 2020

Male-to-female sex reversal in M33 mutant mice

1 reference

12 December 2020

Bmi-1 is useful as a novel molecular marker for predicting progression of myelodysplastic syndrome and patient prognosis

1 reference

12 December 2020

Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus

1 reference

12 December 2020

Purification and unique properties of mammary epithelial stem cells

1 reference

12 December 2020

A novel member of murine Polycomb-group proteins, Sex comb on midleg homolog protein, is highly conserved, and interacts with RAE28/mph1 in vitro

1 reference

12 December 2020

RNAi-dependent H3K27 methylation is required for heterochromatin formation and DNA elimination in Tetrahymena

1 reference

12 December 2020

Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia

1 reference

12 December 2020

Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing

1 reference

12 December 2020

Mel-18 acts as a tumor suppressor by repressing Bmi-1 expression and down-regulating Akt activity in breast cancer cells

1 reference

12 December 2020

Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains

1 reference

12 December 2020

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

1 reference

12 December 2020

Bmi-1 is a target gene for SALL4 in hematopoietic and leukemic cells

1 reference

12 December 2020

Geminin bans replication licence

1 reference

12 December 2020

PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention

1 reference

12 December 2020

Structural basis for specific binding of Polycomb chromodomain to histone H3 methylated at Lys 27

1 reference

12 December 2020

Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

1 reference

12 December 2020

10.1007/S12185-007-0006-Y

Identifiers

DOI

1 reference

17 September 2017

1 reference

PubMed ID

18224410