Ajuba negatively regulates the Wnt signaling pathway by promoting GSK-3beta-mediated phosphorylation of beta-catenin. (Q40109326)

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1 January 2020

title

Ajuba negatively regulates the Wnt signaling pathway by promoting GSK-3beta-mediated phosphorylation of beta-catenin (English)

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1 January 2020

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3

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1 January 2020

author name string

K Haraguchi

1

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1 January 2020

M Ohsugi

2

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1 January 2020

K Semba

4

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1 January 2020

T Akiyama

5

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1 January 2020

T Yamamoto

6

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1 January 2020

language of work or name

English

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publication date

9 July 2007

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1 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17621269%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

volume

27

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1 January 2020

issue

3

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1 January 2020

page(s)

274-284

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1210644

1 January 2020

exact match

0 references

cites work

Role of a BCL9-related beta-catenin-binding protein, B9L, in tumorigenesis induced by aberrant activation of Wnt signaling

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Linking colorectal cancer to Wnt signaling

21 January 2018

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LIM domains: multiple roles as adapters and functional modifiers in protein interactions

21 January 2018

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

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Wnt-3A/beta-catenin signaling induces transcription from the LEF-1 promoter

21 January 2018

1 reference

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Ajuba, a novel LIM protein, interacts with Grb2, augments mitogen-activated protein kinase activity in fibroblasts, and promotes meiotic maturation of Xenopus oocytes in a Grb2- and Ras-dependent manner

21 January 2018

1 reference

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Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

21 January 2018

1 reference

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Ajuba, a cytosolic LIM protein, shuttles into the nucleus and affects embryonal cell proliferation and fate decisions

21 January 2018

1 reference

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Interaction and functional cooperation between the LIM protein FHL2, CBP/p300, and beta-catenin

21 January 2018

1 reference

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Acetylation of beta-catenin by p300 regulates beta-catenin-Tcf4 interaction

21 January 2018

1 reference

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Axin and Frat1 interact with dvl and GSK, bridging Dvl to GSK in Wnt-mediated regulation of LEF-1.

21 January 2018

1 reference

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Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway

21 January 2018

1 reference

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The LIM-only protein FHL2 interacts with beta-catenin and promotes differentiation of mouse myoblasts

21 January 2018

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Signal transduction through beta-catenin and specification of cell fate during embryogenesis

21 January 2018

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Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleus

21 January 2018

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The LIM protein Ajuba influences p130Cas localization and Rac1 activity during cell migration

21 January 2018

1 reference

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Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts

21 January 2018

1 reference

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Cytoskeletal reorganization by soluble Wnt-3a protein signalling

21 January 2018

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The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway

21 January 2018

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A mechanism for Wnt coreceptor activation

21 January 2018

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Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

21 January 2018

1 reference

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Wg/Wnt signal can be transmitted through arrow/LRP5,6 and Axin independently of Zw3/Gsk3beta activity

21 January 2018

1 reference

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Identification of the LIM protein FHL2 as a coactivator of beta-catenin

21 January 2018

1 reference

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Wnt signaling: a common theme in animal development

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1210644

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17621269%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

1 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17621269%20AND%20SRC:MED&resulttype=core&format=json