Functional importance of charged residues within the putative intracellular loops in pH regulation by Na+/ H+ exchanger NHE1. (Q40100915)

17 September 2017

title

Functional importance of charged residues within the putative intracellular loops in pH regulation by Na+/ H+ exchanger NHE1. (English)

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17 September 2017

Takashi Hisamitsu

1

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17 September 2017

Keiji Yamada

series ordinal

2

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17 September 2017

Tomoe Y Nakamura

series ordinal

3

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17 September 2017

Shigeo Wakabayashi

series ordinal

4

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17 September 2017

language of work or name

English

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publication date

27 July 2007

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17 September 2017

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17 September 2017

volume

274

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17 September 2017

issue

16

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17 September 2017

page(s)

4326-4335

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Diversity of the mammalian sodium/proton exchanger SLC9 gene family

17 September 2017

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Kinetic dissection of two distinct proton binding sites in Na+/H+ exchangers by measurement of reverse mode reaction

21 January 2018

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Dimeric interaction between the cytoplasmic domains of the Na+/H+ exchanger NHE1 revealed by symmetrical intermolecular cross-linking and selective co-immunoprecipitation

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Dimerization is crucial for the function of the Na+/H+ exchanger NHE1.

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Identification of cytoplasmic subdomains that control pH-sensing of the Na+/H+ exchanger (NHE1): pH-maintenance, ATP-sensitive, and flexible loop domains

21 January 2018

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Role of calcineurin B homologous protein in pH regulation by the Na+/H+ exchanger 1: tightly bound Ca2+ ions as important structural elements

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Calcineurin homologous protein as an essential cofactor for Na+/H+ exchangers

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Crystal structure of CHP2 complexed with NHE1-cytosolic region and an implication for pH regulation

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Mutations of Arg440 and Gly455/Gly456 oppositely change pH sensing of Na+/H+ exchanger 1.

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A mechanism for the activation of the Na/H exchanger NHE-1 by cytoplasmic acidification and mitogens

21 January 2018

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A specific mutation abolishing Na+/H+ antiport activity in hamster fibroblasts precludes growth at neutral and acidic pH

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Membrane curvature alters the activation kinetics of the epithelial Na+/H+ exchanger, NHE3.

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21 January 2018

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Two histidine residues in the juxta-membrane cytoplasmic domain of Na+/H+ exchanger isoform 3 (NHE3) determine the set point

21 January 2018

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Identification of membrane domains of the Na+/H+ antiporter (NhaA) protein from Helicobacter pylori required for ion transport and pH sensing

21 January 2018

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Multiconformation continuum electrostatics analysis of the NhaA Na+/H+ antiporter of Escherichia coli with functional implications

21 January 2018

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A point mutation of the Na+/H+ exchanger gene (NHE1) and amplification of the mutated allele confer amiloride resistance upon chronic acidosis

21 January 2018

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Proline residues in transmembrane segment IV are critical for activity, expression and targeting of the Na+/H+ exchanger isoform 1.

21 January 2018

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Glutamate 346 of human Na+-H+ exchanger NHE1 is crucial for modulating both the affinity for Na+ and the interaction with amiloride derivatives

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Identification of sites in the second exomembrane loop and ninth transmembrane helix of the mammalian Na+/H+ exchanger important for drug recognition and cation translocation.

21 January 2018

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Structural and functional characterization of transmembrane segment IV of the NHE1 isoform of the Na+/H+ exchanger

21 January 2018

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pH-induced structural change in a sodium/proton antiporter from Methanococcus jannaschii

21 January 2018

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Structure of a Na+/H+ antiporter and insights into mechanism of action and regulation by pH.

21 January 2018

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Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters

21 January 2018

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A Slow pH-dependent Conformational Transition Underlies a Novel Mode of Activation of the Epithelial Na+/H+Exchanger-3 Isoform

21 January 2018

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Modifier role of internal H+ in activating the Na+–H+ exchanger in renal microvillus membrane vesicles

21 January 2018

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10.1111/J.1742-4658.2007.05962.X

21 January 2018

Identifiers

DOI

1 reference

17 September 2017

1 reference