Diversity of the mammalian sodium/proton exchanger SLC9 gene family (Q28185218)

https://scigraph.springernature.com/pub.10.1007/s00424-003-1110-3

Europe PubMed Central

title

Diversity of the mammalian sodium/proton exchanger SLC9 gene family (English)

0 references

0 references

2

Sergio Grinstein

0 references

author name string

John Orlowski

series ordinal

1

0 references

language of work or name

English

0 references

publication date

February 2004

0 references

published in

Pfluegers Archiv

0 references

volume

447

0 references

page(s)

549-65

0 references

issue

5

0 references

exact match

0 references

cites work

Proton dependence of the partial reactions of the sodium-proton exchanger in renal brush border membranes

1 reference

12 December 2020

Functional properties of the rat Na/H exchanger NHE-2 isoform expressed in Na/H exchanger-deficient Chinese hamster ovary cells

1 reference

12 December 2020

Ischemic-reperfusion injury in the kidney: overexpression of colonic H+-K+-ATPase and suppression of NHE-3

1 reference

12 December 2020

A specific mutation abolishing Na+/H+ antiport activity in hamster fibroblasts precludes growth at neutral and acidic pH

1 reference

12 December 2020

Na+/H+ exchange mediates meal-stimulated ileal absorption

1 reference

12 December 2020

Intracellular pH regulation of CA1 neurons in Na(+)/H(+) isoform 1 mutant mice

1 reference

12 December 2020

Molecular cloning, genomic organization, and functional expression of Na+/H+ exchanger isoform 5 (NHE5) from human brain

1 reference

12 December 2020

Endosomal recycling of the Na+/H+ exchanger NHE3 isoform is regulated by the phosphatidylinositol 3-kinase pathway.

1 reference

12 December 2020

cAMP-mediated inhibition of the epithelial brush border Na+/H+ exchanger, NHE3, requires an associated regulatory protein

1 reference

12 December 2020

Delineation of transmembrane domains of the Na+/H+ exchanger that confer sensitivity to pharmacological antagonists

1 reference

12 December 2020

The role of vesicular transport proteins in synaptic transmission and neural degeneration

1 reference

12 December 2020

Characterization of the rat Na+/H+ exchanger isoform NHE4 and localization in rat hippocampus

1 reference

12 December 2020

Pathophysiology of acute ischaemic stroke

1 reference

12 December 2020

Molecular cloning, primary structure, and expression of the human growth factor-activatable Na+/H+ antiporter

1 reference

12 December 2020

Kinetic properties of the plasma membrane Na+-H+ exchanger

1 reference

12 December 2020

Molecular cloning and physical and genetic mapping of a novel human Na+/H+ exchanger (NHE5/SLC9A5) to chromosome 16q22.1

1 reference

12 December 2020

Role of brush border Na+/H+ exchange in canine ileal absorption

1 reference

12 December 2020

Increased Na(+)-H+ exchanger activity in the ileal brush-border membrane of spontaneously hypertensive rats

1 reference

12 December 2020

Role of Na(+)/H(+) exchanger NHE3 in nephron function: micropuncture studies with S3226, an inhibitor of NHE3

1 reference

12 December 2020

Na(+)/H(+) exchanger 3 is in large complexes in the center of the apical surface of proximal tubule-derived OK cells

1 reference

12 December 2020

Sodium/hydrogen exchanger gene defect in slow-wave epilepsy mutant mice.

1 reference

12 December 2020

Mutations of Arg440 and Gly455/Gly456 oppositely change pH sensing of Na+/H+ exchanger 1.

1 reference

12 December 2020

Macula densa Na(+)/H(+) exchange activities mediated by apical NHE2 and basolateral NHE4 isoforms

1 reference

12 December 2020

Na(+)/H(+) antiporters.

1 reference

12 December 2020

Intracellular pH regulation by Na(+)/H(+) exchange requires phosphatidylinositol 4,5-bisphosphate.

1 reference

12 December 2020

Modification of the internal pH sensitivity of the Na+/H+ antiporter by parathyroid hormone in a cultured renal cell line

1 reference

12 December 2020

Distinct structural domains confer cAMP sensitivity and ATP dependence to the Na+/H+ exchanger NHE3 isoform

1 reference

12 December 2020

Genetic and biochemical determinants of abnormal monovalent ion transport in primary hypertension.

1 reference

12 December 2020

The NHX family of Na+-H+ exchangers in Caenorhabditis elegans

1 reference

12 December 2020

Role of cytoplasmic domain of the Na+/H+ exchanger in hormonal activation.

1 reference

12 December 2020

Acute inhibition of Na/H exchanger NHE-3 by cAMP. Role of protein kinase a and NHE-3 phosphoserines 552 and 605.

1 reference

12 December 2020

The importance of being acid: the role of acidification in intracellular membrane traffic

1 reference

12 December 2020

The sodium/proton exchanger Nhx1p is required for endosomal protein trafficking in the yeast Saccharomyces cerevisiae

1 reference

12 December 2020

Dual mechanisms of regulation of Na/H exchanger NHE-3 by parathyroid hormone in rat kidney.

1 reference

12 December 2020

Targeted disruption of the murine Na+/H+ exchanger isoform 2 gene causes reduced viability of gastric parietal cells and loss of net acid secretion

1 reference

12 December 2020

Separate C-terminal domains of the epithelial specific brush border Na+/H+ exchanger isoform NHE3 are involved in stimulation and inhibition by protein kinases/growth factors

1 reference

12 December 2020

Identification of a mitochondrial Na+/H+ exchanger

1 reference

12 December 2020

Molecular cloning and functional expression of a rat Na+/H+ exchanger (NHE5) highly expressed in brain

1 reference

12 December 2020

Mitochondrial cation transport systems

1 reference

12 December 2020

Renal salt wasting in mice lacking NHE3 Na+/H+ exchanger but not in mice lacking NHE2.

1 reference

12 December 2020

In vivo PTH provokes apical NHE3 and NaPi2 redistribution and Na-K-ATPase inhibition

1 reference

12 December 2020

Redistribution of Na+/H+ exchanger isoform NHE3 in proximal tubules induced by acute and chronic hypertension

1 reference

12 December 2020

Direct binding of the Na--H exchanger NHE1 to ERM proteins regulates the cortical cytoskeleton and cell shape independently of H(+) translocation

1 reference

12 December 2020

Differential expression and function of Arabidopsis thaliana NHX Na+/H+ antiporters in the salt stress response.

1 reference

12 December 2020

Expression of calcineurin B homologous protein 2 protects serum deprivation-induced cell death by serum-independent activation of Na+/H+ exchanger

1 reference

12 December 2020

S3226, a novel inhibitor of Na+/H+ exchanger subtype 3 in various cell types

1 reference

12 December 2020

Autosomal dominant spinocerebellar ataxia with sensory axonal neuropathy (SCA4): clinical description and genetic localization to chromosome 16q22.1

1 reference

12 December 2020

Role of NHE isoforms in mediating bicarbonate reabsorption along the nephron

1 reference

12 December 2020

Protein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes

1 reference

12 December 2020

Enhanced mitogen-activated protein kinase activity and phosphorylation of the Na+/H+ exchanger isoform-1 of human lymphoblasts in hypertension

1 reference

12 December 2020

RhoA and rho kinase regulate the epithelial Na+/H+ exchanger NHE3. Role of myosin light chain phosphorylation

1 reference

12 December 2020

Regulation of the formation of tumor cell pseudopodia by the Na(+)/H(+) exchanger NHE1.

1 reference

12 December 2020

Cell migration requires both ion translocation and cytoskeletal anchoring by the Na-H exchanger NHE1.

1 reference

12 December 2020

Brain ischemia and reperfusion: molecular mechanisms of neuronal injury

1 reference

12 December 2020

Mechanism of acidification of the trans-Golgi network (TGN). In situ measurements of pH using retrieval of TGN38 and furin from the cell surface

1 reference

12 December 2020

Interrelationships among quinidine, amiloride, and lithium as inhibitors of the renal Na+-H+ exchanger

1 reference

12 December 2020

The Na(+)/H(+) exchanger SM-20220 attenuates ischemic injury in in vitro and in vivo models

1 reference

12 December 2020

NHE3 kinase A regulatory protein E3KARP binds the epithelial brush border Na+/H+ exchanger NHE3 and the cytoskeletal protein ezrin

1 reference

12 December 2020

Impaired cell volume regulation in Na(+)-H+ exchange-deficient mutants

1 reference

12 December 2020

Identification of sites in the second exomembrane loop and ninth transmembrane helix of the mammalian Na+/H+ exchanger important for drug recognition and cation translocation.

1 reference

12 December 2020

Isolation and properties of fibroblast mutants overexpressing an altered Na+/H+ antiporter.

1 reference

12 December 2020

Primary structure and functional expression of a novel gastrointestinal isoform of the rat Na/H exchanger.

1 reference

12 December 2020

Activity and expression of Na(+)-H+ exchanger isoforms 1 and 3 in kidney proximal tubules of hypertensive rats

1 reference

12 December 2020

Calcineurin homologous protein as an essential cofactor for Na+/H+ exchangers

1 reference

12 December 2020

Human Na(+)/H(+) exchanger isoform 6 is found in recycling endosomes of cells, not in mitochondria

1 reference

12 December 2020

Molecular structure and physiological function of chloride channels

1 reference

12 December 2020

Calmodulin-binding autoinhibitory domain controls "pH-sensing" in the Na+/H+ exchanger NHE1 through sequence-specific interaction

1 reference

12 December 2020

Acute regulation of NHE3 by protein kinase A requires a multiprotein signal complex

1 reference

12 December 2020

Three-dimensional structure of the ion-coupled transport protein NhaA.

1 reference

12 December 2020

Heterologous expression of rat NHE4: a highly amiloride-resistant Na+/H+ exchanger isoform

1 reference

12 December 2020

Topological analysis of NHE1, the ubiquitous Na+/H+ exchanger using chymotryptic cleavage

1 reference

12 December 2020

Cloning and expression of a rabbit cDNA encoding a serum-activated ethylisopropylamiloride-resistant epithelial Na+/H+ exchanger isoform (NHE-2).

1 reference

12 December 2020

Immunocytochemical characterization of Na(+)-H+ exchanger isoform NHE-1 in rabbit kidney

1 reference

12 December 2020

Na+/H+ exchangers of mammalian cells.

1 reference

12 December 2020

Cloning, tissue distribution, and functional analysis of the human Na+/N+ exchanger isoform, NHE3

1 reference

12 December 2020

Molecular size of the Na+-H+ antiport in renal brush border membranes, as estimated by radiation inactivation.

1 reference

12 December 2020

14-3-3 proteins interact with specific MEK kinases

1 reference

12 December 2020

Immunochemical characterization of Na+/H+ exchanger isoform NHE4.

1 reference

12 December 2020

Muscarinic receptor-induced acidification in sublingual mucous acinar cells: loss of pH recovery in Na+-H+ exchanger-1 deficient mice

1 reference

12 December 2020

Hyposmolality stimulates apical membrane Na(+)/H(+) exchange and HCO(3)(-) absorption in renal thick ascending limb

1 reference

12 December 2020

Kinetic and pharmacological properties of human brain Na(+)/H(+) exchanger isoform 5 stably expressed in Chinese hamster ovary cells

1 reference

12 December 2020

Interactions of chloride and amiloride with the renal Na+/H/ antiporter

1 reference

12 December 2020

Heterologous expression and functional properties of amiloride high affinity (NHE-1) and low affinity (NHE-3) isoforms of the rat Na/H exchanger

1 reference

12 December 2020

NHE2 and NHE3 are human and rabbit intestinal brush-border proteins

1 reference

12 December 2020

Variations of intracellular pH in human erythrocytes via K(+)(Na(+))/H(+) exchange under low ionic strength conditions

1 reference

12 December 2020

Human homolog of mouse tescalcin associates with Na(+)/H(+) exchanger type-1

1 reference

12 December 2020

Sodium dependence of the Na(+)-H+ exchanger in the pre-steady state. Implications for the exchange mechanism.

1 reference

12 December 2020

Renal expression of novel Na+/H+ exchanger isoform NHE8

1 reference

12 December 2020

Measurement of cytosolic, mitochondrial, and Golgi pH in single living cells with green fluorescent proteins

1 reference

12 December 2020

NHE3: a Na+/H+ exchanger isoform of renal brush border

1 reference

12 December 2020

Sodium-hydrogen exchange and glucose transport in renal microvillus membrane vesicles from rats with diabetes mellitus

1 reference

12 December 2020

Functional characterization of three isoforms of the Na+/H+ exchanger stably expressed in Chinese hamster ovary cells. ATP dependence, osmotic sensitivity, and role in cell proliferation

1 reference

12 December 2020

Role of sodium-hydrogen exchange in cardiac hypertrophy and heart failure: a novel and promising therapeutic target

1 reference

12 December 2020

The epithelial sodium-hydrogen antiporter Na+/H+ exchanger 3 accumulates and is functional in recycling endosomes

1 reference

12 December 2020

The apical Na(+)/H(+) exchanger isoform NHE3 is regulated by the actin cytoskeleton

1 reference

12 December 2020

Regulation of cardiac Na+,Ca2+ exchange and KATP potassium channels by PIP2.

1 reference

12 December 2020

Specific modulation of Kex2/furin family proteases by potassium

1 reference

12 December 2020

p160ROCK mediates RhoA activation of Na-H exchange

1 reference

12 December 2020

Mutational analysis of transmembrane histidines in the amiloride-sensitive Na+/H+ exchanger

1 reference

12 December 2020

Molecular cloning and characterization of a novel (Na+,K+)/H+ exchanger localized to the trans-Golgi network

1 reference

12 December 2020

1 reference

12 December 2020

Exclusion of the Na(+)-H+ antiporter as a candidate gene in human essential hypertension

1 reference

12 December 2020

Acute inhibition of brain-specific Na(+)/H(+) exchanger isoform 5 by protein kinases A and C and cell shrinkage

1 reference

12 December 2020

Immunolocalization of the Na+/H+ exchanger isoform NHE2 in rat kidney

1 reference

12 December 2020

Random mutagenesis reveals a novel site involved in inhibitor interaction within the fourth transmembrane segment of the Na+/H+ exchanger-1

1 reference

12 December 2020

The Na+/H+ antiporter cytoplasmic domain mediates growth factor signals and controls "H(+)-sensing"

1 reference

12 December 2020

A novel topology model of the human Na(+)/H(+) exchanger isoform 1

1 reference

12 December 2020

Regulation of the epithelial Na(+) /H(+) exchanger isoform by the cytoskeleton

1 reference

12 December 2020

Molecular cloning, tissue distribution, and functional expression of the human Na(+)/H(+) exchanger NHE2

1 reference

12 December 2020

Second-site revertants of a low-sodium-affinity mutant of the Na+/H+ exchanger reveal the participation of TM4 into a highly constrained sodium-binding site

1 reference

12 December 2020

A calcineurin homologous protein inhibits GTPase-stimulated Na-H exchange

1 reference

12 December 2020

Subcellular localization of the Na+/H+ exchanger NHE1 in rat myocardium

1 reference

12 December 2020

The Na+/H+ exchange isoform NHE3 regulates basal canine ileal Na+ absorption in vivo

1 reference

12 December 2020

Molecular cloning of putative members of the Na/H exchanger gene family. cDNA cloning, deduced amino acid sequence, and mRNA tissue expression of the rat Na/H exchanger NHE-1 and two structurally related proteins

1 reference

12 December 2020

Identification of sites required for down-regulation of Na+/H+ exchanger NHE3 activity by cAMP-dependent protein kinase. phosphorylation-dependent and -independent mechanisms

1 reference

12 December 2020

Defective fluid secretion and NaCl absorption in the parotid glands of Na+/H+ exchanger-deficient mice

1 reference

12 December 2020

Molecular cloning and expression of a cDNA encoding the rabbit ileal villus cell basolateral membrane Na+/H+ exchanger

1 reference

12 December 2020

Renal and intestinal absorptive defects in mice lacking the NHE3 Na+/H+ exchanger.

1 reference

12 December 2020

NHE6 protein possesses a signal peptide destined for endoplasmic reticulum membrane and localizes in secretory organelles of the cell

1 reference

12 December 2020

14-3-3 Binding to Na+/H+ exchanger isoform-1 is associated with serum-dependent activation of Na+/H+ exchange

1 reference

12 December 2020

Proline-rich motifs of the Na+/H+ exchanger 2 isoform. Binding of Src homology domain 3 and role in apical targeting in epithelia.

1 reference

12 December 2020

Focal localization of the NHE-1 isoform of the Na+/H+ antiport: assessment of effects on intracellular pH.

1 reference

12 December 2020

Mutation of calmodulin-binding site renders the Na+/H+ exchanger (NHE1) highly H(+)-sensitive and Ca2+ regulation-defective

1 reference

12 December 2020

Involvement of the M7/M8 extracellular loop of the sodium pump alpha subunit in ion transport. Structural and functional homology to P-loops of ion channels

1 reference

12 December 2020

A point mutation of the Na+/H+ exchanger gene (NHE1) and amplification of the mutated allele confer amiloride resistance upon chronic acidosis

1 reference

12 December 2020

Sodium-hydrogen exchange inhibition: novel strategy to prevent myocardial injury following ischemia and reperfusion

1 reference

12 December 2020

Localization and functional characterization of Na+/H+ exchanger isoform NHE4 in rat thick ascending limbs.

1 reference

12 December 2020

The Na+/H+ exchanger NHE-1 possesses N- and O-linked glycosylation restricted to the first N-terminal extracellular domain

1 reference

12 December 2020

Regulation of intracellular pH in the rabbit cortical collecting tubule

1 reference

12 December 2020

Inhibition of Na+-H+ exchanger-3 interferes with apical receptor-mediated endocytosis via vesicle fusion

1 reference

12 December 2020

Salt tolerance conferred by overexpression of a vacuolar Na+/H+ antiport in Arabidopsis

1 reference

12 December 2020

Clathrin-mediated endocytosis and recycling of the neuron-specific Na+/H+ exchanger NHE5 isoform. Regulation by phosphatidylinositol 3'-kinase and the actin cytoskeleton

1 reference

12 December 2020

ATP dependence of NHE-1, the ubiquitous isoform of the Na+/H+ antiporter. Analysis of phosphorylation and subcellular localization.

1 reference

12 December 2020

Evidence that Na+/H+ exchanger isoforms NHE1 and NHE3 exist as stable dimers in membranes with a high degree of specificity for homodimers.

1 reference

12 December 2020

Expression of NHE-3 in the apical membrane of rat renal proximal tubule and thick ascending limb

1 reference

12 December 2020

Association of Na(+)-H(+) exchanger isoform NHE3 and dipeptidyl peptidase IV in the renal proximal tubule

1 reference

12 December 2020

TreeView: an application to display phylogenetic trees on personal computers

1 reference

12 December 2020

Molecular physiology of vertebrate Na+/H+ exchangers

1 reference

12 December 2020

Role of the cytoskeleton in mediating cAMP-dependent protein kinase inhibition of the epithelial Na+/H+ exchanger NHE3.

1 reference

12 December 2020

Na+/H+ exchanger-2 is an O-linked but not an N-linked sialoglycoprotein

1 reference

12 December 2020

Pharmacological characterization of stably transfected Na+/H+ antiporter isoforms using amiloride analogs and a new inhibitor exhibiting anti-ischemic properties.

1 reference

12 December 2020

Cloning and expression of a chloride-dependent Na+-H+ exchanger

1 reference

12 December 2020

The Nck-interacting kinase (NIK) phosphorylates the Na+-H+ exchanger NHE1 and regulates NHE1 activation by platelet-derived growth factor

1 reference

12 December 2020

Increased neuronal excitability and seizures in the Na(+)/H(+) exchanger null mutant mouse

1 reference

12 December 2020

p90(RSK) is a serum-stimulated Na+/H+ exchanger isoform-1 kinase. Regulatory phosphorylation of serine 703 of Na+/H+ exchanger isoform-1

1 reference

12 December 2020

Protective effects of HOE642, a selective sodium-hydrogen exchange subtype 1 inhibitor, on cardiac ischaemia and reperfusion

1 reference

12 December 2020

Gap junctional conductance between pairs of ventricular myocytes is modulated synergistically by H+ and Ca++.

1 reference

12 December 2020

The myocardial Na(+)-H(+) exchange: structure, regulation, and its role in heart disease

1 reference

12 December 2020

Carbonic anhydrase II binds to and enhances activity of the Na+/H+ exchanger

1 reference

12 December 2020

Characterization of a protein cofactor that mediates protein kinase A regulation of the renal brush border membrane Na(+)-H+ exchanger

1 reference

12 December 2020

The putative plasma membrane Na(+)/H(+) antiporter SOS1 controls long-distance Na(+) transport in plants

1 reference

12 December 2020

Organelle acidification and disease

1 reference

12 December 2020

Ezrin is a cyclic AMP-dependent protein kinase anchoring protein

1 reference

12 December 2020

Specific association of megalin and the Na+/H+ exchanger isoform NHE3 in the proximal tubule

1 reference

12 December 2020

Monoclonal antibodies for high-resolution localization of NHE3 in adult and neonatal rat kidney

1 reference

12 December 2020

Modification of gap junction conductance by divalent cations and protons in neonatal rat heart cells

1 reference

12 December 2020

Targeted disruption of the murine Nhe1 locus induces ataxia, growth retardation, and seizures.

1 reference

12 December 2020

Cloning and sequencing of a rabbit cDNA encoding an intestinal and kidney-specific Na+/H+ exchanger isoform (NHE-3)

1 reference

12 December 2020

Defective jejunal brush-border Na+/H+ exchange: a cause of congenital secretory diarrhoea

1 reference

12 December 2020

Structure and properties of the vacuolar (H+)-ATPases

1 reference

12 December 2020

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1 reference

12 December 2020

Determinants of the pH of the Golgi complex

1 reference

12 December 2020

5-(N-ethyl-N-isopropyl)amiloride and mild acidosis protect cultured cerebellar granule cells against glutamate-induced delayed neuronal death

1 reference

12 December 2020

The plasma membrane sodium-hydrogen exchanger and its role in physiological and pathophysiological processes

1 reference

12 December 2020

Regulation of cardiac Ca2+ release channel (ryanodine receptor) by Ca2+, H+, Mg2+, and adenine nucleotides under normal and simulated ischemic conditions

1 reference

12 December 2020

Identification of EBP50: A PDZ-containing phosphoprotein that associates with members of the ezrin-radixin-moesin family

1 reference

12 December 2020

Membrane topology of NHE3. Epitopes within the carboxyl-terminal hydrophilic domain are exoplasmic

1 reference

12 December 2020

A 90-kD Na(+)-H+ exchanger kinase has increased activity in spontaneously hypertensive rat vascular smooth muscle cells

1 reference

12 December 2020

Apical membrane Na+/H+ exchange in rat medullary thick ascending limb. pH-dependence and inhibition by hyperosmolality

1 reference

12 December 2020

The changing face of the Na+/H+ exchanger, NHE1: structure, regulation, and cellular actions

1 reference

12 December 2020

Direct involvement of ezrin/radixin/moesin (ERM)-binding membrane proteins in the organization of microvilli in collaboration with activated ERM proteins

1 reference

12 December 2020

Na(+)/H(+) exchanger NHE3 has 11 membrane spanning domains and a cleaved signal peptide: topology analysis using in vitro transcription/translation.

1 reference

12 December 2020

Active (9.6 s) and inactive (21 s) oligomers of NHE3 in microdomains of the renal brush border

1 reference

12 December 2020

Topology of the C-terminus of sodium hydrogen exchanger isoform-1: presence of an extracellular epitope

1 reference

12 December 2020

The epithelial Na(+)/H(+) exchanger, NHE3, is internalized through a clathrin-mediated pathway

1 reference

12 December 2020