Evidence that sprouty 2 is necessary for sarcoma formation by H-Ras oncogene-transformed human fibroblasts (Q40042536)

16 September 2017

Evidence that sprouty 2 is necessary for sarcoma formation by H-Ras oncogene-transformed human fibroblasts (English)

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16 September 2017

Piro Lito

1

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16 September 2017

Bryan D Mets

2

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16 September 2017

Susanne Kleff

3

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16 September 2017

Sandra O'Reilly

4

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16 September 2017

Veronica M Maher

5

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16 September 2017

J Justin McCormick

6

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16 September 2017

language of work or name

English

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publication date

28 November 2007

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Journal of Biological Chemistry

16 September 2017

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16 September 2017

283

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16 September 2017

2002-2009

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16 September 2017

4

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Analysis of the multistep process of carcinogenesis using human fibroblasts

16 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

Characteristics of an infinite life span diploid human fibroblast cell strain and a near-diploid strain arising from a clone of cells expressing a transfected v-myc oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

Malignant transformation of human fibroblasts caused by expression of a transfected T24 HRAS oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

Dose-dependent transformation of cells of human fibroblast cell strain MSU-1.1 by cobalt-60 gamma radiation and characterization of the transformed cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

Sprouty, an intracellular inhibitor of Ras signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

Cloning and expression pattern of a mouse homologue of drosophila sprouty in the mouse embryo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

The bimodal regulation of epidermal growth factor signaling by human Sprouty proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

Mammalian sprouty proteins inhibit cell growth and differentiation by preventing ras activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

Mammalian sprouty-1 and -2 are membrane-anchored phosphoprotein inhibitors of growth factor signaling in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

The C terminus of sprouty is important for modulation of cellular migration and proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

Raf-1 kinase activation is uncoupled from downstream MEK/ERK pathway in cells treated with Src tyrosine kinase inhibitor PP2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

Tyrosine phosphorylation of Sprouty2 enhances its interaction with c-Cbl and is crucial for its function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

Tyrosine phosphorylation of Sprouty proteins regulates their ability to inhibit growth factor signaling: a dual feedback loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

Sprouty fine-tunes EGF signaling through interlinked positive and negative feedback loops

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

Evidence for direct interaction between Sprouty and Cbl

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

Spatial regulation of EGFR signaling by Sprouty2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

Cbl: many adaptations to regulate protein tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

Modulation of signalling by Sprouty: a developing story

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

The ras/mitogen-activated protein kinase pathway inhibitor and likely tumor suppressor proteins, sprouty 1 and sprouty 2 are deregulated in breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

Sprouty 2, an inhibitor of mitogen-activated protein kinase signaling, is down-regulated in hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

Concomitant down-regulation of SPRY1 and SPRY2 in prostate carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

Sprouty4, a suppressor of tumor cell motility, is down regulated by DNA methylation in human prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

A negative feedback signaling network underlies oncogene-induced senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

Sprouty-2 regulates oncogenic K-ras in lung development and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

Effect of common B-RAF and N-RAS mutations on global gene expression in melanoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

Cloning and characterization of a novel gene encoding a putative transmembrane protein with altered expression in some human transformed and tumor-derived cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

Gene expression profiling of human sarcomas: insights into sarcoma biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

A raf-independent epidermal growth factor receptor autocrine loop is necessary for Ras transformation of rat intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

Oncogenic Ha-Ras-dependent mitogen-activated protein kinase activity requires signaling through the epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

RAS transformation causes sustained activation of epidermal growth factor receptor and elevation of mitogen-activated protein kinase in human mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

The EGF receptor provides an essential survival signal for SOS-dependent skin tumor development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

Tyrosine kinase inhibition: an approach to drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

Dual effects of Sprouty1 on TCR signaling depending on the differentiation state of the T cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

Down-regulation of Sprouty2 in non-small cell lung cancer contributes to tumor malignancy via extracellular signal-regulated kinase pathway-dependent and -independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

Hyperactive Ras in developmental disorders and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

Sprouty-2 overexpression in C2C12 cells confers myogenic differentiation properties in the presence of FGF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

Sprouty2 acts at the Cbl/CIN85 interface to inhibit epidermal growth factor receptor downregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

Molecular characterisation of soft tissue tumours: a gene expression study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M709046200

21 January 2018

Identifiers

DOI

10.1074/JBC.M709046200

1 reference

16 September 2017

1 reference