Interleukin-21 regulates expression of key Epstein-Barr virus oncoproteins, EBNA2 and LMP1, in infected human B cells (Q40020299)

16 September 2017

Interleukin-21 regulates expression of key Epstein-Barr virus oncoproteins, EBNA2 and LMP1, in infected human B cells (English)

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16 September 2017

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Danijela Konforte

1

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16 September 2017

Nathalie Simard

series ordinal

2

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16 September 2017

Christopher J Paige

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3

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16 September 2017

language of work or name

English

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publication date

28 January 2008

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16 September 2017

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16 September 2017

374

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16 September 2017

1

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16 September 2017

100-113

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Reversal of EBV immortalization precedes apoptosis in IL-6-induced human B cell terminal differentiation

16 September 2017

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Cutting edge: the common gamma-chain is an indispensable subunit of the IL-21 receptor complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

The expression pattern of Epstein-Barr virus latent genes in vivo is dependent upon the differentiation stage of the infected B cell

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Interleukin-21 is a growth and survival factor for human myeloma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Epstein-Barr virus LMP2A drives B cell development and survival in the absence of normal B cell receptor signals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Identification of a promoter for the latent membrane protein 1 gene of Epstein-Barr virus that is specifically activated in human epithelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

A positive autoregulatory loop of LMP1 expression and STAT activation in epithelial cells latently infected with Epstein-Barr virus.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

The Epstein-Barr virus latency BamHI-Q promoter is positively regulated by STATs and Zta interference with JAK/STAT activation leads to loss of BamHI-Q promoter activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Linkage between STAT regulation and Epstein-Barr virus gene expression in tumors

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Epstein-Barr virus nuclear protein 2 is a key determinant of lymphocyte transformation

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Interleukin-21 receptor (IL-21R) is up-regulated by CD40 triggering and mediates proapoptotic signals in chronic lymphocytic leukemia B cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Urokinase activates the Jak/Stat signal transduction pathway in human vascular endothelial cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

IL-21 induces differentiation of human naive and memory B cells into antibody-secreting plasma cells.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Kinetics of human B cell behavior and amplification of proliferative responses following stimulation with IL-21.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Constitutive CD40 signaling phenocopies the transforming function of the Epstein-Barr virus oncoprotein LMP1 in vitro

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Viral interactions with the Notch pathway

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Activated Notch1 can transiently substitute for EBNA2 in the maintenance of proliferation of LMP1-expressing immortalized B cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Distinct activation signals determine whether IL-21 induces B cell costimulation, growth arrest, or Bim-dependent apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Epstein-Barr virus nuclear antigen 2-estrogen receptor fusion proteins transactivate viral and cellular genes and interact with RBP-J kappa in a conditional fashion.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

In vitro EBV-infected subline of KMH2, derived from Hodgkin lymphoma, expresses only EBNA-1, while CD40 ligand and IL-4 induce LMP-1 but not EBNA-2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

IL-10 can induce the expression of EBV-encoded latent membrane protein-1 (LMP-1) in the absence of EBNA-2 in B lymphocytes and in Burkitt lymphoma- and NK lymphoma-derived cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Cytokine mediated induction of the major Epstein-Barr virus (EBV)-encoded transforming protein, LMP-1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Identification of cellular intermediates and molecular pathways induced by IL-21 in human B cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Essential role of IL-21 in B cell activation, expansion, and plasma cell generation during CD4+ T cell-B cell collaboration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

The dispersal of mucosal memory B cells: evidence from persistent EBV infection.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Interleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiation

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Antigen-specific memory B cell development

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

NFATc2 and T-bet contribute to T-helper-cell-subset-specific regulation of IL-21 expression

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Interleukin 21: a key player in lymphocyte maturation

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

CD40 ligation downregulates EBNA-2 and LMP-1 expression in EBV-transformed lymphoblastoid cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

c-myc activation renders proliferation of Epstein-Barr virus (EBV)-transformed cells independent of EBV nuclear antigen 2 and latent membrane protein 1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Redefining the Epstein-Barr virus-encoded nuclear antigen EBNA-1 gene promoter and transcription initiation site in group I Burkitt lymphoma cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

PU box-binding transcription factors and a POU domain protein cooperate in the Epstein-Barr virus (EBV) nuclear antigen 2-induced transactivation of the EBV latent membrane protein 1 promoter

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Domains of the Epstein-Barr virus nuclear antigen 2 (EBNA2) involved in the transactivation of the latent membrane protein 1 and the EBNA Cp promoters

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Engagement of protein kinase C-theta in interferon signaling in T-cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Concomitant increase of LMP1 and CD25 (IL-2-receptor alpha) expression induced by IL-10 in the EBV-positive NK lines SNK6 and KAI3.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Photochemical preparation of a pyridone containing tetracycle: a Jak protein kinase inhibitor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Epstein-Barr virus: exploiting the immune system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

EBV the prototypical human tumor virus--just how bad is it?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Persistence of the Epstein-Barr virus and the origins of associated lymphomas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Mimicry of CD40 signals by Epstein-Barr virus LMP1 in B lymphocyte responses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Follicular B helper T cells in antibody responses and autoimmunity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Anomalous behaviour of the STAT3 binding site in the human c-myc P2 promoter.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Epstein-Barr virus: 40 years on

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Relative levels of EBNA1 gene transcripts from the C/W, F and Q promoters in Epstein-Barr virus-transformed lymphoid cells in latent and lytic stages of infection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

RNAs induced by Epstein-Barr virus nuclear antigen 2 in lymphoblastoid cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

EBNA2 and Notch signalling in Epstein-Barr virus mediated immortalization of B lymphocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Growth hormone attenuates the transcriptional activity of Runx2 by facilitating its physical association with Stat3beta

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

Epstein-Barr virus nuclear antigen 2 induces expression of the virus-encoded latent membrane protein.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

7 January 2021

Stable transfection of Epstein-Barr virus (EBV) nuclear antigen 2 in lymphoma cells containing the EBV P3HR1 genome induces expression of B-cell activation molecules CD21 and CD23.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

7 January 2021

Identification and characterization of an Epstein-Barr virus nuclear antigen 2-responsive cis element in the bidirectional promoter region of latent membrane protein and terminal protein 2 genes.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

7 January 2021

Transcription start sites downstream of the Epstein-Barr virus (EBV) Fp promoter in early-passage Burkitt lymphoma cells define a fourth promoter for expression of the EBV EBNA-1 protein

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

7 January 2021

The Epstein-Barr virus 3.5-kilobase latent membrane protein 1 mRNA initiates from a TATA-Less promoter within the first terminal repeat

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

7 January 2021

Epstein-Barr virus nuclear antigen 2 transactivates latent membrane protein LMP1.

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2007.12.027

7 January 2021

10.1016/J.VIROL.2007.12.027

Identifiers

DOI

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16 September 2017

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