Runx2-mediated activation of the Bax gene increases osteosarcoma cell sensitivity to apoptosis. (Q40020072)

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1 January 2020

title

Runx2-mediated activation of the Bax gene increases osteosarcoma cell sensitivity to apoptosis (English)

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1 January 2020

4

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1 January 2020

author name string

R A Eliseev

1

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1 January 2020

Y-F Dong

2

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1 January 2020

E Sampson

3

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1 January 2020

E M Schwarz

5

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1 January 2020

R J O'Keefe

6

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1 January 2020

R N Rosier

7

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1 January 2020

M H Drissi

8

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1 January 2020

language of work or name

English

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publication date

28 January 2008

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1 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18223689%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

volume

27

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1 January 2020

issue

25

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1 January 2020

page(s)

3605-3614

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1211020

1 January 2020

exact match

0 references

cites work

The Bcl-2 protein family: arbiters of cell survival

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How do Bax and Bak lead to permeabilization of the outer mitochondrial membrane?

21 January 2018

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Tumor suppressor activity of RUNX3.

21 January 2018

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Phosphorylation, acetylation and ubiquitination: the molecular basis of RUNX regulation

21 January 2018

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The RUNX genes: gain or loss of function in cancer

21 January 2018

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Apoptosis-inducing factor (AIF): a novel caspase-independent death effector released from mitochondria

21 January 2018

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Runx transcription factors and the developmental balance between cell proliferation and differentiation.

21 January 2018

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The Bcl2 family: regulators of the cellular life-or-death switch

21 January 2018

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Identification of novel protein/DNA interactions within the promoter of the bone-related transcription factor Runx2/Cbfa1.

21 January 2018

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Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation

21 January 2018

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The bone-specific expression of Runx2 oscillates during the cell cycle to support a G1-related antiproliferative function in osteoblasts

21 January 2018

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Inhibition of growth of mouse gastric cancer cells by Runx3, a novel tumor suppressor

21 January 2018

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Runx3 controls the axonal projection of proprioceptive dorsal root ganglion neurons

21 January 2018

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The Runt domain identifies a new family of heteromeric transcriptional regulators.

21 January 2018

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HES1 cooperates with pRb to activate RUNX2-dependent transcription

21 January 2018

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Causal relationship between the loss of RUNX3 expression and gastric cancer

21 January 2018

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Breaking the mitochondrial barrier

21 January 2018

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A novel form of Epstein-Barr virus latency in normal B cells in vivo

21 January 2018

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t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1

21 January 2018

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Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia

21 January 2018

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Caspase structure, proteolytic substrates, and function during apoptotic cell death

21 January 2018

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Current topics in pharmacological research on bone metabolism: regulation of bone mass by the function of endogenous modulators of bone morphogenetic protein in adult stage

21 January 2018

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Growth- and tumor-promoting effects of deregulated BCL2 in human B-lymphoblastoid cells

21 January 2018

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AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

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Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype.

21 January 2018

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Cytochrome c: can't live with it--can't live without it.

21 January 2018

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Proapoptotic multidomain Bcl-2/Bax-family proteins: mechanisms, physiological roles, and therapeutic opportunities

21 January 2018

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RUNX3 inhibits cell proliferation and induces apoptosis by reinstating transforming growth factor beta responsiveness in esophageal adenocarcinoma cells

21 January 2018

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Mitochondrial intermembrane proteins in cell death

21 January 2018

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Nomenclature for Runt-related (RUNX) proteins

21 January 2018

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Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

21 January 2018

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Life in the balance: how BH3-only proteins induce apoptosis.

21 January 2018

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The RUNX3 tumor suppressor upregulates Bim in gastric epithelial cells undergoing transforming growth factor beta-induced apoptosis

21 January 2018

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Prostate cancer expression of runt‐domain transcription factor Runx2, a key regulator of osteoblast differentiation and function

21 January 2018

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12 December 2020

Dysregulation of apoptosis in cancer

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12 December 2020

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12 December 2020

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

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12 December 2020

Execution of BMP-4-induced apoptosis by p53-dependent ER dysfunction in myeloma and B-cell hybridoma cells

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12 December 2020

Cell growth regulatory role of Runx2 during proliferative expansion of preosteoblasts

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12 December 2020

Biology of osteogenic sarcoma

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12 December 2020

Requisite roles of Runx2 and Cbfb in skeletal development

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12 December 2020

Hematopoietic malignancies demonstrate loss-of-function mutations of BAX

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12 December 2020

How does the human RUNX3 gene induce apoptosis in gastric cancer? Latest data, reflections and reactions

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12 December 2020

Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma

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12 December 2020

Identifiers

DOI

10.1038/SJ.ONC.1211020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18223689%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

1 January 2020

0 references

1 reference

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1 January 2020

1 reference