Domains involved in calcineurin phosphatase inhibition and nuclear localisation in the African swine fever virus A238L protein (Q40015060)

16 September 2017

title

Domains involved in calcineurin phosphatase inhibition and nuclear localisation in the African swine fever virus A238L protein (English)

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African swine fever virus

16 September 2017

main subject

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Charles C Abrams

1

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16 September 2017

Dave A G Chapman

2

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16 September 2017

Rhiannon Silk

3

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16 September 2017

Elisabetta Liverani

4

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16 September 2017

Linda K Dixon

5

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16 September 2017

language of work or name

English

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publication date

7 February 2008

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16 September 2017

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16 September 2017

volume

374

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16 September 2017

issue

2

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16 September 2017

page(s)

477-486

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Selective inhibition of NFAT activation by a peptide spanning the calcineurin targeting site of NFAT

16 September 2017

cites work

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Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A.

7 January 2021

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Functional characterization of the calcipressin 1 motif that suppresses calcineurin-mediated NFAT-dependent cytokine gene expression in human T cells

7 January 2021

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Measurement of Calcineurin Phosphatase Activity in Cell Extracts

7 January 2021

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Two-site interaction of nuclear factor of activated T cells with activated calcineurin

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The viral protein A238L inhibits TNF-alpha expression through a CBP/p300 transcriptional coactivators pathway

7 January 2021

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The viral protein A238L inhibits cyclooxygenase-2 expression through a nuclear factor of activated T cell-dependent transactivation pathway

7 January 2021

1 reference

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Regulation of inducible nitric oxide synthase expression by viral A238L-mediated inhibition of p65/RelA acetylation and p300 transactivation

7 January 2021

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SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

7 January 2021

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Transcriptional regulation by calcium, calcineurin, and NFAT

7 January 2021

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The crystal structure of the IkappaBalpha/NF-kappaB complex reveals mechanisms of NF-kappaB inactivation

7 January 2021

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Structure of calcineurin in complex with PVIVIT peptide: portrait of a low-affinity signalling interaction

7 January 2021

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Endogenous protein inhibitors of calcineurin

7 January 2021

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Inhibitors of the calcineurin/NFAT pathway.

7 January 2021

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A viral mechanism for inhibition of the cellular phosphatase calcineurin.

7 January 2021

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African swine fever virus protein A238L interacts with the cellular phosphatase calcineurin via a binding domain similar to that of NFAT.

7 January 2021

1 reference

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A nonessential African swine fever virus gene UK is a significant virulence determinant in domestic swine

7 January 2021

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Feedback inhibition of calcineurin and Ras by a dual inhibitory protein Carabin

7 January 2021

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A second calcineurin binding site on the NFAT regulatory domain

7 January 2021

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Inhibition of nuclear factor kappaB activation by a virus-encoded IkappaB-like protein

7 January 2021

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A conserved docking site modulates substrate affinity for calcineurin, signaling output, and in vivo function

7 January 2021

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African swine fever virus A238L inhibitor of NF-kappaB and of calcineurin phosphatase is imported actively into the nucleus and exported by a CRM1-mediated pathway.

7 January 2021

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Cabin 1, a negative regulator for calcineurin signaling in T lymphocytes

7 January 2021

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Mechanism of inactivation of NF-kappa B by a viral homologue of I kappa b alpha. Signal-induced release of i kappa b alpha results in binding of the viral homologue to NF-kappa B.

7 January 2021

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Structure of the Calcineurin-NFAT Complex: Defining a T Cell Activation Switch Using Solution NMR and Crystal Coordinates

7 January 2021

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Diversity and regulation in the NF-kappaB system

7 January 2021

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10.1016/J.VIROL.2008.01.005

7 January 2021

Identifiers

DOI

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16 September 2017

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