Site-specific blockade of RAGE-Vd prevents amyloid-beta oligomer neurotoxicity (Q39982408)

16 September 2017

Site-specific blockade of RAGE-Vd prevents amyloid-beta oligomer neurotoxicity (English)

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16 September 2017

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Emmanuel Sturchler

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670634&resulttype=core&format=json

16 May 2020

Arnaud Galichet

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670634&resulttype=core&format=json

16 May 2020

Mirjam Weibel

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670634&resulttype=core&format=json

16 May 2020

Estelle Leclerc

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670634&resulttype=core&format=json

16 May 2020

Claus W Heizmann

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670634&resulttype=core&format=json

16 May 2020

language of work or name

English

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publication date

1 May 2008

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16 September 2017

Journal of Neuroscience

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670634&resulttype=core&format=json

16 May 2020

volume

28

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16 May 2020

issue

20

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16 May 2020

page(s)

5149-5158

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RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides

16 May 2020

cites work

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12 December 2020

Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

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12 December 2020

Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline

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12 December 2020

Coregulation of neurite outgrowth and cell survival by amphoterin and S100 proteins through receptor for advanced glycation end products (RAGE) activation

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12 December 2020

Immunohistochemical distribution of the receptor for advanced glycation end products in neurons and astrocytes in Alzheimer's disease.

1 reference

12 December 2020

Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease

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12 December 2020

Receptor for advanced glycation end products plays a more important role in cellular survival than in neurite outgrowth during retinoic acid-induced differentiation of neuroblastoma cells

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12 December 2020

The relationship between Abeta and memory in the Tg2576 mouse model of Alzheimer's disease.

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12 December 2020

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

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12 December 2020

Aberrant activation of focal adhesion proteins mediates fibrillar amyloid beta-induced neuronal dystrophy.

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12 December 2020

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

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12 December 2020

RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain

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12 December 2020

The receptor for advanced glycation end-products (RAGE) directly binds to ERK by a D-domain-like docking site

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12 December 2020

Isolation and characterization of two binding proteins for advanced glycosylation end products from bovine lung which are present on the endothelial cell surface

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12 December 2020

Beta-amyloid-activated cell cycle in SH-SY5Y neuroblastoma cells: correlation with the MAP kinase pathway.

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12 December 2020

Membrane cholesterol interferes with neuronal apoptosis induced by soluble oligomers but not fibrils of amyloid-beta peptide

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12 December 2020

Overexpression of receptor of advanced glycation end products hypersensitizes cells for amyloid beta peptide-induced cell death.

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12 December 2020

Beta-amyloid peptide at sublethal concentrations downregulates brain-derived neurotrophic factor functions in cultured cortical neurons.

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12 December 2020

MAPK recruitment by beta-amyloid in organotypic hippocampal slice cultures depends on physical state and exposure time

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12 December 2020

RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice

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12 December 2020

Synaptic targeting by Alzheimer's-related amyloid beta oligomers.

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12 December 2020

Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function

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12 December 2020

Nucleation-dependent polymerization is an essential component of amyloid-mediated neuronal cell death.

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12 December 2020

Beta-amyloid-induced neuronal apoptosis involves c-Jun N-terminal kinase-dependent downregulation of Bcl-w.

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12 December 2020

RAGE and amyloid beta interactions: atomic force microscopy and molecular modeling.

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12 December 2020

Fine structure study of Aβ1-42 fibrillogenesis with atomic force microscopy

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12 December 2020

Endogenous beta-amyloid peptide synthesis modulates cAMP response element-regulated gene expression in PC12 cells

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12 December 2020

Docosahexaenoic acid prevents neuronal apoptosis induced by soluble amyloid-beta oligomers

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12 December 2020

Alpha2beta1 and alphaVbeta1 integrin signaling pathways mediate amyloid-beta-induced neurotoxicity

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12 December 2020

Astroglial activation of extracellular-regulated kinase in early stages of Alzheimer disease

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12 December 2020

Effects of secreted oligomers of amyloid beta-protein on hippocampal synaptic plasticity: a potent role for trimers.

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12 December 2020

High-resolution atomic force microscopy of soluble Abeta42 oligomers

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12 December 2020

Activation of ERK1/2 MAP kinases in familial amyloidotic polyneuropathy

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12 December 2020

A specific amyloid-beta protein assembly in the brain impairs memory

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12 December 2020

Soluble oligomers of amyloid-beta peptide induce neuronal apoptosis by activating a cPLA2-dependent sphingomyelinase-ceramide pathway

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12 December 2020

High resolution scanning tunnelling microscopy of the beta-amyloid protein (Abeta1-40) of Alzheimer's disease suggests a novel mechanism of oligomer assembly.

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12 December 2020

ERK1/2 activation mediates Abeta oligomer-induced neurotoxicity via caspase-3 activation and tau cleavage in rat organotypic hippocampal slice cultures.

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12 December 2020

Different conformations of amyloid beta induce neurotoxicity by distinct mechanisms in human cortical neurons.

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12 December 2020

Expression and purification of the soluble isoform of human receptor for advanced glycation end products (sRAGE) from Pichia pastoris.

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12 December 2020

Acceleration of amyloid beta-peptide aggregation by physiological concentrations of calcium

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12 December 2020

Abeta42 is more rigid than Abeta40 at the C terminus: implications for Abeta aggregation and toxicity.

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12 December 2020

Hexameric calgranulin C (S100A12) binds to the receptor for advanced glycated end products (RAGE) using symmetric hydrophobic target-binding patches

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12 December 2020

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

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12 December 2020

A Oligomer-Induced Aberrations in Synapse Composition, Shape, and Density Provide a Molecular Basis for Loss of Connectivity in Alzheimer's Disease

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12 December 2020

Differential binding and activation of caspase-3 in cultured hippocampal neurons by assembly forms of A beta 1-42.

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12 December 2020

Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE

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12 December 2020

Metal ions differentially influence the aggregation and deposition of Alzheimer's beta-amyloid on a solid template.

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12 December 2020

Abeta40 protects non-toxic Abeta42 monomer from aggregation

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12 December 2020

The extracellular region of the receptor for advanced glycation end products is composed of two independent structural units.

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12 December 2020

Amyloid formation via supramolecular peptide assemblies.

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12 December 2020

Formation of amyloid fibrils via longitudinal growth of oligomers

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12 December 2020

Modulation of amyloid-β-induced and age-associated changes in rat hippocampus by eicosapentaenoic acid

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12 December 2020

S100B and S100A6 differentially modulate cell survival by interacting with distinct RAGE (receptor for advanced glycation end products) immunoglobulin domains

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12 December 2020

Evidence of Abeta- and transgene-dependent defects in ERK-CREB signaling in Alzheimer's models

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12 December 2020

Integrins mediate beta-amyloid-induced cell-cycle activation and neuronal death.

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12 December 2020

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12 December 2020

Soluble Abeta inhibits specific signal transduction cascades common to the insulin receptor pathway.

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12 December 2020

Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

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12 December 2020

Cytotoxicity of Abeta1-42, RAGE23-54, and an Abeta-RAGE complex in PC-12 cells.

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12 December 2020

Correlations of synaptic and pathological markers with cognition of the elderly

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12 December 2020

Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

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12 December 2020

Expression in brain of amyloid precursor protein mutated in the alpha-secretase site causes disturbed behavior, neuronal degeneration and premature death in transgenic mice.

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12 December 2020

RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease

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12 December 2020

Amyloid-beta peptide-receptor for advanced glycation endproduct interaction elicits neuronal expression of macrophage-colony stimulating factor: a proinflammatory pathway in Alzheimer disease

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12 December 2020

Activation of the receptor for advanced glycation end products triggers a p21(ras)-dependent mitogen-activated protein kinase pathway regulated by oxidant stress.

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12 December 2020

Abeta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse.

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12 December 2020

APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1.

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12 December 2020

Aggregated amyloid-beta protein induces cortical neuronal apoptosis and concomitant "apoptotic" pattern of gene induction.

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12 December 2020

Binding of beta-amyloid to the p75 neurotrophin receptor induces apoptosis. A possible mechanism for Alzheimer's disease.

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12 December 2020

Quantifying amyloid beta-peptide (Abeta) aggregation using the Congo red-Abeta (CR-abeta) spectrophotometric assay.

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12 December 2020

10.1523/JNEUROSCI.4878-07.2008

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670634&resulttype=core&format=json

16 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6670634&resulttype=core&format=json

16 May 2020

1 reference