Analysis of Ret knockin mice reveals a critical role for IKKs, but not PI 3-K, in neurotrophic factor-induced survival of sympathetic neurons. (Q39979628)

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English	Analysis of Ret knockin mice reveals a critical role for IKKs, but not PI 3-K, in neurotrophic factor-induced survival of sympathetic neurons.	scientific article

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scholarly article

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7 January 2020

Analysis of Ret knockin mice reveals a critical role for IKKs, but not PI 3-K, in neurotrophic factor-induced survival of sympathetic neurons (English)

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7 January 2020

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7 January 2020

Joan X. Comella

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7 January 2020

Jeffrey Milbrandt

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7 January 2020

author name string

E J Rozen

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7 January 2020

X Dolcet

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7 January 2020

E M Johnson

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23 May 2008

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7 January 2020

Cell Death & Differentiation

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15

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7 January 2020

1510-1521

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9

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7 January 2020

https://scigraph.springernature.com/pub.10.1038/cdd.2008.76

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Raf kinase signaling functions in sensory neuron differentiation and axon growth in vivo

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22 September 2017

The RET/PTC-RAS-BRAF linear signaling cascade mediates the motile and mitogenic phenotype of thyroid cancer cells

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The RAF proteins take centre stage

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22 September 2017

Dok-6, a Novel p62 Dok family member, promotes Ret-mediated neurite outgrowth

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22 September 2017

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22 September 2017

IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a

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22 September 2017

Tyrosine 981, a novel ret autophosphorylation site, binds c-Src to mediate neuronal survival

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22 September 2017

Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting MKK7/JNKK2

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Critical function of endogenous XIAP in regulating caspase activation during sympathetic neuronal apoptosis

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22 September 2017

Interaction between Src and a C-terminal proline-rich motif of Akt is required for Akt activation

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22 September 2017

POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis.

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22 September 2017

Essential role of PDK1 in regulating cell size and development in mice

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22 September 2017

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22 September 2017

Intrinsic and extrinsic pathway signaling during neuronal apoptosis: lessons from the analysis of mutant mice

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22 September 2017

IAPs are essential for GDNF-mediated neuroprotective effects in injured motor neurons in vivo

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22 September 2017

Evidence for a role of mixed lineage kinases in neuronal apoptosis

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22 September 2017

Docking protein FRS2 links the protein tyrosine kinase RET and its oncogenic forms with the mitogen-activated protein kinase signaling cascade

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22 September 2017

GDNF family neurotrophic factor signaling: four masters, one servant?

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22 September 2017

Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons.

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22 September 2017

Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor

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Induction of gadd45beta by NF-kappaB downregulates pro-apoptotic JNK signalling.

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25 September 2017

Signaling complexes and protein-protein interactions involved in the activation of the Ras and phosphatidylinositol 3-kinase pathways by the c-Ret receptor tyrosine kinase.

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Role of the Jun kinase pathway in the regulation of c-Jun expression and apoptosis in sympathetic neurons.

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17 June 2018

Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons

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20 August 2018

FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons

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20 August 2018

Src family protein-tyrosine kinases alter the function of PTEN to regulate phosphatidylinositol 3-kinase/AKT cascades

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4 November 2018

Ferritin Heavy Chain Upregulation by NF-κB Inhibits TNFα-Induced Apoptosis by Suppressing Reactive Oxygen Species

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Specific function of B-Raf in mediating survival of embryonic motoneurons and sensory neurons

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12 December 2020

based on heuristic

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Superoxide dismutase delays neuronal apoptosis: a role for reactive oxygen species in programmed neuronal death

1 reference

https://pubmed.ncbi.nlm.nih.gov/18497757

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death

1 reference

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12 December 2020

based on heuristic

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Expression of human copper/zinc-superoxide dismutase inhibits the death of rat sympathetic neurons caused by withdrawal of nerve growth factor

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nerve growth factor-dependent activation of NF-kappaB contributes to survival of sympathetic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/18497757

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylinositol 3-kinase is required for the trophic, but not the survival-promoting, actions of NGF on sympathetic neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/18497757

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/CDD.2008.76

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7 January 2020

1 reference

Europe PubMed Central

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7 January 2020

1 reference

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7 January 2020

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