Substitution of hexon hypervariable region 5 of adenovirus serotype 5 abrogates blood factor binding and limits gene transfer to liver (Q39971490)

16 September 2017

Substitution of hexon hypervariable region 5 of adenovirus serotype 5 abrogates blood factor binding and limits gene transfer to liver (English)

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Michel Jean Robert Perricaudet

16 September 2017

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object named as

Michel Perricaudet

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16 September 2017

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Karim Benihoud

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16 September 2017

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Paule Opolon

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16 September 2017

Frédéric Vigant

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16 September 2017

Delphyne Descamps

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16 September 2017

Betsy Jullienne

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16 September 2017

Stéphanie Esselin

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16 September 2017

Elisabeth Connault

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16 September 2017

Thierry Tordjmann

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16 September 2017

Emmanuelle Vigne

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16 September 2017

language of work or name

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17 June 2008

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16 September 2017

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16 September 2017

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16 September 2017

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16 September 2017

1474-1480

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CAR: a virus receptor within the tight junction

16 September 2017

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https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

Adenovirus endocytosis.

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https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

https://api.crossref.org/works/10.1038%2FMT.2008.132

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7 January 2021

The influence of adenovirus fiber structure and function on vector development for gene therapy

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https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

In vivo hepatic adenoviral gene delivery occurs independently of the coxsackievirus-adenovirus receptor

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https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

Genetic targeting of adenoviral vectors

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https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

Genetic manipulations of adenovirus type 5 fiber resulting in liver tropism attenuation

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https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

Reduction of natural adenovirus tropism to the liver by both ablation of fiber-coxsackievirus and adenovirus receptor interaction and use of replaceable short fiber

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

A human adenoviral vector with a chimeric fiber from canine adenovirus type 1 results in novel expanded tropism for cancer gene therapy

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https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

CD46 is a cellular receptor for group B adenoviruses

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

Adenovirus vector pseudotyping in fiber-expressing cell lines: improved transduction of Epstein-Barr virus-transformed B cells

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https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

Simultaneous CAR- and alpha V integrin-binding ablation fails to reduce Ad5 liver tropism

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https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

Adenovirus serotype 5 fiber shaft influences in vivo gene transfer in mice

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https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

Adenovirus 5 fibers mutated at the putative HSPG-binding site show restricted retargeting with targeting peptides in the HI loop

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

Role of the putative heparan sulfate glycosaminoglycan-binding site of the adenovirus type 5 fiber shaft on liver detargeting and knob-mediated retargeting

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

Bioluminescence imaging reveals a significant role for complement in liver transduction following intravenous delivery of adenovirus

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https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

Adenovirus Binding to Blood Factors Results in Liver Cell Infection and Hepatotoxicity

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https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes

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https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

The influence of blood on in vivo adenovirus bio-distribution and transduction.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

Influence of coagulation factor zymogens on the infectivity of adenoviruses pseudotyped with fibers from subgroup D.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

Targeting of adenovirus serotype 5 (Ad5) and 5/47 pseudotyped vectors in vivo: fundamental involvement of coagulation factors and redundancy of CAR binding by Ad5.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

Modulation of TNFalpha, a determinant of acute toxicity associated with systemic delivery of first-generation and helper-dependent adenoviral vectors

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https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

Blood clearance rates of adenovirus type 5 in mice

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https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

Selective depletion or blockade of Kupffer cells leads to enhanced and prolonged hepatic transgene expression using high-capacity adenoviral vectors

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

Adenovirus serotype 5 hexon mediates liver gene transfer

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

Development of renal-targeted vectors through combined in vivo phage display and capsid engineering of adenoviral fibers from serotype 19p.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

Adenovirus serotype 5 hexon is critical for virus infection of hepatocytes in vivo

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

Elimination of innate immune responses and liver inflammation by PEGylation of adenoviral vectors and methylprednisolone

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

Fiber-modified adenovirus vectors decrease liver toxicity through reduced IL-6 production

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

Import of adenovirus DNA involves the nuclear pore complex receptor CAN/Nup214 and histone H1.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

Characterization of in vitro and in vivo gene transfer properties of adenovirus serotype 35 vector

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

Hexon-chimaeric adenovirus serotype 5 vectors circumvent pre-existing anti-vector immunity

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

Identification of sites in adenovirus hexon for foreign peptide incorporation

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https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

An improved anion-exchange HPLC method for the detection and purification of adenoviral particles

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https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

Remodelling of calcium signalling during liver regeneration in the rat.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.132

7 January 2021

Identifiers

DOI

10.1038/MT.2008.132

1 reference

16 September 2017

1 reference