Development of renal-targeted vectors through combined in vivo phage display and capsid engineering of adenoviral fibers from serotype 19p. (Q33286806)

25 July 2017

Development of renal-targeted vectors through combined in vivo phage display and capsid engineering of adenoviral fibers from serotype 19p. (English)

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25 July 2017

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Lorraine M Work

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Stuart A Nicklin

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Stuart A Nicklin

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John H. McVey

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John H McVey

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Laura Denby

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25 July 2017

Dan J Von Seggern

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25 July 2017

Eugene Wu

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25 July 2017

Andrew H Baker

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25 July 2017

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Robust systemic transduction with AAV9 vectors in mice: efficient global cardiac gene transfer superior to that of AAV8.

25 July 2017

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Systemic delivery of genes to striated muscles using adeno-associated viral vectors.

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Efficient transduction of skeletal muscle using vectors based on adeno-associated virus serotype 6.

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Recombinant adeno-associated virus serotype 9 leads to preferential cardiac transduction in vivo

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

CD46 is a cellular receptor for group B adenoviruses

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

A new group B adenovirus receptor is expressed at high levels on human stem and tumor cells.

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Improved adenovirus vectors for infection of cardiovascular tissues

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Tropism-modified adenoviral and adeno-associated viral vectors for gene therapy

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Effect of adenovirus serotype 5 fiber and penton modifications on in vivo tropism in rats

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Adenovirus serotype 5 fiber shaft influences in vivo gene transfer in mice

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Receptor interactions involved in adenoviral-mediated gene delivery after systemic administration in non-human primates

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Adenovirus Binding to Blood Factors Results in Liver Cell Infection and Hepatotoxicity

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Adenoviral serotype 5 vectors pseudotyped with fibers from subgroup D show modified tropism in vitro and in vivo.

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Combined transductional and transcriptional targeting improves the specificity of transgene expression in vivo

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Organ targeting in vivo using phage display peptide libraries

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Reversal of obesity by targeted ablation of adipose tissue

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Molecular heterogeneity of the vascular endothelium revealed by in vivo phage display

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Steps toward mapping the human vasculature by phage display.

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Anti-cancer activity of targeted pro-apoptotic peptides

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Ablating adenovirus type 5 fiber-CAR binding and HI loop insertion of the SIGYPLP peptide generate an endothelial cell-selective adenovirus

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Animal cell mutants defective in glycosaminoglycan biosynthesis

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Vascular bed-targeted in vivo gene delivery using tropism-modified adeno-associated viruses

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

An adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a coxsackievirus and adenovirus receptor-independent cell entry mechanism

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Adenovirus type 5 interactions with human blood cells may compromise systemic delivery.

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Multiple innate inflammatory responses induced after systemic adenovirus vector delivery depend on a functional complement system.

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Bioluminescence imaging reveals a significant role for complement in liver transduction following intravenous delivery of adenovirus

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Analysis of adenovirus sequestration in the liver, transduction of hepatic cells, and innate toxicity after injection of fiber-modified vectors

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Heparan sulfate glycosaminoglycans are involved in adenovirus type 5 and 2-host cell interactions

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Heparan sulfate glycosaminoglycans are receptors sufficient to mediate the initial binding of adenovirus types 2 and 5.

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Adenovirus 5 fibers mutated at the putative HSPG-binding site show restricted retargeting with targeting peptides in the HI loop

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Influence of coagulation factor zymogens on the infectivity of adenoviruses pseudotyped with fibers from subgroup D.

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Adenovirus type 37 uses sialic acid as a cellular receptor

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Suppression of glomerulosclerosis by adenovirus-mediated IL-10 expression in the kidney

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Inhibition of renal fibrosis by gene transfer of inducible Smad7 using ultrasound-microbubble system in rat UUO model

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Adrenomedullin gene delivery attenuates renal damage and cardiac hypertrophy in Goldblatt hypertensive rats

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Gene therapy by skeletal muscle expression of decorin prevents fibrotic disease in rat kidney

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Adenovirus vector pseudotyping in fiber-expressing cell lines: improved transduction of Epstein-Barr virus-transformed B cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Adenovirus type 5 viral particles pseudotyped with mutagenized fiber proteins show diminished infectivity of coxsackie B-adenovirus receptor-bearing cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Crystal structure of species D adenovirus fiber knobs and their sialic acid binding sites

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https://api.crossref.org/works/10.1038%2FSJ.MT.6300214

7 January 2021

Identifiers

DOI

10.1038/SJ.MT.6300214

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25 July 2017

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