Leukemia suppressor function of Egr-1 is dependent on transforming oncogene (Q39957933)

15 September 2017

Leukemia suppressor function of Egr-1 is dependent on transforming oncogene (English)

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15 September 2017

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J D Gibbs

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D A Liebermann

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2

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B Hoffman

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3

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24 July 2008

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22

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1909-1916

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https://scigraph.springernature.com/pub.10.1038/leu.2008.189

15 September 2017

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cites work

Interleukin-6- and leukemia inhibitory factor-induced terminal differentiation of myeloid leukemia cells is blocked at an intermediate stage by constitutive c-myc

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https://api.crossref.org/works/10.1038%2FLEU.2008.189

The zinc finger transcription factor Egr-1 is essential for and restricts differentiation along the macrophage lineage

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2008.189

Deregulated c-myb disrupts interleukin-6- or leukemia inhibitory factor-induced myeloid differentiation prior to c-myc: role in leukemogenesis

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2008.189

The zinc finger transcription factor Egr-1 potentiates macrophage differentiation of hematopoietic cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2008.189

Early growth response gene 1 stimulates development of hematopoietic progenitor cells along the macrophage lineage at the expense of the granulocyte and erythroid lineages

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2008.189

Multilineage transcriptional priming and determination of alternate hematopoietic cell fates.

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2008.189

Egr-1 abrogates the block imparted by c-Myc on terminal M1 myeloid differentiation

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2008.189

Egr-1 abrogates the E2F-1 block in terminal myeloid differentiation and suppresses leukemia

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2008.189

Several chromosomes involved in translocations with chromosome 5 shown with fluorescence in situ hybridization in patients with malignant myeloid disorders

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2008.189

Clinical, morphological, cytogenetic, and prognostic features of patients with myelodysplastic syndromes and del(5q) including band q31

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2008.189

Haploinsufficiency of EGR1, a candidate gene in the del(5q), leads to the development of myeloid disorders

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2008.189

Targeting c-Myb expression in human disease

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2008.189

c-Myb is an essential downstream target for homeobox-mediated transformation of hematopoietic cells.

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2008.189

Requirement of c-Myb for p210(BCR/ABL)-dependent transformation of hematopoietic progenitors and leukemogenesis

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2008.189

Up-regulation of Egr1 by 1,25-dihydroxyvitamin D3 contributes to increased expression of p35 activator of cyclin-dependent kinase 5 and consequent onset of the terminal phase of HL60 cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.189

The transcription factor EGR-1 suppresses transformation of human fibrosarcoma HT1080 cells by coordinated induction of transforming growth factor-beta1, fibronectin, and plasminogen activator inhibitor-1.

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2008.189

p21Cip1 gene expression is modulated by Egr1: a novel regulatory mechanism involved in the resveratrol antiproliferative effect.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2008.189

A function of p21 during promyelocytic leukemia cell differentiation independent of CDK inhibition and cell cycle arrest.

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2008.189

Differentiation of functional dendritic cells and macrophages from human peripheral blood monocyte precursors is dependent on expression of p21 (WAF1/CIP1) and requires iron

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2008.189

p21cip1 is required for the differentiation of oligodendrocytes independently of cell cycle withdrawal.

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2008.189

Terminal myeloid differentiation is uncoupled from cell cycle arrest

21 January 2018

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https://api.crossref.org/works/10.1038%2FLEU.2008.189

21 January 2018

Identifiers

DOI

10.1038/LEU.2008.189

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Dimensions Publication ID

15 September 2017

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